HESI LPN
HESI Practice Test Pharmacology
1. A client with diabetes mellitus is prescribed insulin glargine. What information should the practical nurse (PN) provide to the client about this medication?
- A. Administer the insulin at mealtimes.
- B. Do not mix this insulin with other insulins.
- C. Shake the vial well before use.
- D. Store the insulin in the freezer.
Correct answer: B
Rationale: Insulin glargine is a long-acting insulin that should not be mixed with other insulins in the same syringe. Mixing it with other insulins can alter its pharmacokinetics and effectiveness. Insulin glargine is usually administered at the same time each day, often at bedtime, to provide a consistent basal level of insulin over 24 hours.
2. A client with diabetes mellitus type 2 is prescribed liraglutide. The nurse should include which instruction in the client's teaching plan?
- A. Administer this medication once a week.
- B. Administer this medication once a month.
- C. Administer this medication twice a day.
- D. Administer this medication once a day.
Correct answer: D
Rationale: The correct answer is to administer liraglutide once a day. Liraglutide is typically prescribed to be taken once daily, as directed by the healthcare provider. This dosing schedule helps maintain consistent levels of the medication in the body to effectively manage blood sugar levels in clients with diabetes mellitus type 2. Option A, administering once a week, is incorrect as it would not provide consistent control of blood sugar levels. Option B, administering once a month, is also incorrect as it is not the recommended dosing frequency for liraglutide. Option C, administering twice a day, is inaccurate as liraglutide is not typically dosed in this manner. It is important for the nurse to emphasize the importance of adherence to the prescribed dosing regimen to achieve optimal therapeutic outcomes.
3. A client has been taking simvastatin for 3 days and calls the nurse at the clinic to report extreme muscle tenderness and pain. Which is the most appropriate action?
- A. Notify the health care provider.
- B. Review the medication with the client.
- C. Advise the client to avoid grapefruit juice.
- D. Remind the client to limit physical activity until evaluated by the health care provider.
Correct answer: A
Rationale: Extreme muscle tenderness and pain in a client taking simvastatin could indicate rhabdomyolysis, a serious condition. Promptly notifying the health care provider is crucial to evaluate and manage this potential medical emergency. Reviewing the medication with the client may not address the urgency of the situation. Advising the client to avoid grapefruit juice is not directly related to the client's current symptoms. Reminding the client to limit physical activity until evaluated by the health care provider is not appropriate as the client's symptoms should be assessed by a professional first.
4. A client with rheumatoid arthritis is prescribed tofacitinib. What should the nurse include in the client's teaching plan?
- A. Avoid live vaccines while taking this medication.
- B. Take this medication with food to decrease gastrointestinal upset.
- C. Report any signs of infection to the healthcare provider.
- D. Avoid sunlight while taking this medication.
Correct answer: A
Rationale: Tofacitinib is an immunosuppressive medication used in rheumatoid arthritis. Patients taking tofacitinib should avoid live vaccines because the medication can weaken the immune system, making live vaccines potentially harmful. It is essential to educate the client on this to prevent any complications related to live vaccines during their treatment.
5. A client with severe rheumatoid arthritis is prescribed methotrexate. The nurse should monitor the client for which potential adverse effect?
- A. Bone marrow suppression
- B. Increased risk of infection
- C. Liver toxicity
- D. Kidney stones
Correct answer: A
Rationale: The correct answer is A: Bone marrow suppression. Methotrexate, commonly used in rheumatoid arthritis, can lead to bone marrow suppression, reducing the production of blood cells and increasing the risk of infection. Monitoring for signs of anemia, leukopenia, and thrombocytopenia is crucial to detect bone marrow suppression early and prevent complications. Choices B, C, and D are incorrect because while methotrexate can increase the risk of infection, liver toxicity, and kidney issues, the primary concern and most significant adverse effect to monitor for is bone marrow suppression due to its impact on blood cell production.
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