HESI LPN
Pharmacology HESI Practice
1. How does omeprazole work in treating a peptic ulcer?
- A. Increasing the production of gastric acid
- B. Neutralizing stomach acid
- C. Coating the stomach lining
- D. Reducing gastric acid secretion
Correct answer: D
Rationale: Omeprazole is a proton pump inhibitor that works by reducing gastric acid secretion. By inhibiting the enzyme responsible for pumping acid into the stomach, omeprazole helps decrease the acidity level in the stomach, providing relief from peptic ulcers. Option A is incorrect because omeprazole does not increase gastric acid production; instead, it decreases it. Option B is incorrect as omeprazole does not neutralize existing stomach acid but rather reduces its secretion. Option C is incorrect as omeprazole does not coat the stomach lining but acts on reducing acid secretion.
2. A client with hypertension is prescribed lisinopril. The nurse should monitor the client for which potential side effect?
- A. Cough
- B. Dizziness
- C. Hyperkalemia
- D. Hyponatremia
Correct answer: A
Rationale: The correct answer is A: Cough. Lisinopril is known to cause a persistent dry cough as a side effect. It is essential for the nurse to monitor the client for this adverse reaction as it may lead to discontinuation of the medication. Dizziness, hyperkalemia, and hyponatremia are not typically associated with lisinopril use. Dizziness is more commonly seen with antihypertensives that cause orthostatic hypotension. Hyperkalemia and hyponatremia are not usually linked to lisinopril use.
3. A client with chronic kidney disease is prescribed darbepoetin alfa. The nurse should monitor for which potential side effect?
- A. Hypertension
- B. Hypotension
- C. Hyperkalemia
- D. Hyperglycemia
Correct answer: A
Rationale: The correct answer is A: Hypertension. Darbepoetin alfa, used to treat anemia in chronic kidney disease, can lead to hypertension as a side effect. This medication stimulates red blood cell production, which can increase blood pressure. Monitoring blood pressure regularly is crucial to detect and manage this potential adverse effect. Choices B, C, and D are incorrect because hypotension, hyperkalemia, and hyperglycemia are not commonly associated with darbepoetin alfa therapy in chronic kidney disease.
4. The nurse is studying antacids that contain magnesium and calcium for the pharmacology exam. The student nurse remembers that these antacids should be used with caution in patients with which condition?
- A. Hypertension
- B. Renal failure
- C. Heart failure
- D. Peptic ulcer disease
Correct answer: B
Rationale: Magnesium and calcium can accumulate in patients with renal failure, leading to toxicity.
5. A client with chronic kidney disease is prescribed calcium acetate. The nurse should monitor for which potential side effect?
- A. Hypercalcemia
- B. Hypocalcemia
- C. Hyperkalemia
- D. Hypokalemia
Correct answer: A
Rationale: When a client with chronic kidney disease is prescribed calcium acetate, the nurse must monitor for hypercalcemia, not hypocalcemia, hyperkalemia, or hypokalemia. Calcium acetate can increase calcium levels in the blood, leading to hypercalcemia. Symptoms of hypercalcemia include fatigue, confusion, constipation, and muscle weakness. Regular monitoring of calcium levels is crucial to prevent complications associated with elevated calcium levels.
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