HESI LPN
Pharmacology HESI 2023
1. A client with a history of deep vein thrombosis is prescribed warfarin. The nurse should monitor for which potential adverse effect?
- A. Increased risk of bleeding
- B. Decreased risk of bleeding
- C. Increased risk of infection
- D. Decreased risk of infection
Correct answer: A
Rationale: The correct answer is A: Increased risk of bleeding. Warfarin is an anticoagulant medication that works by prolonging the time it takes for blood to clot. Therefore, a potential adverse effect of warfarin is an increased risk of bleeding. It is crucial for the nurse to monitor the client for signs of bleeding, such as easy bruising, prolonged bleeding from cuts, nosebleeds, or blood in the urine or stool. Monitoring for these signs is essential to prevent serious complications associated with excessive bleeding. Choices B, C, and D are incorrect because warfarin does not decrease the risk of bleeding, increase the risk of infection, or decrease the risk of infection. The primary concern with warfarin therapy is the potential for bleeding complications, so close monitoring for signs of bleeding is essential.
2. A client with chronic kidney disease is prescribed darbepoetin alfa. The nurse should monitor for which potential side effect?
- A. Hypertension
- B. Hypotension
- C. Hyperkalemia
- D. Hyperglycemia
Correct answer: A
Rationale: The correct answer is A: Hypertension. Darbepoetin alfa, used to treat anemia in chronic kidney disease, can lead to hypertension as a side effect. This medication stimulates red blood cell production, which can increase blood pressure. Monitoring blood pressure regularly is crucial to detect and manage this potential adverse effect. Choices B, C, and D are incorrect because hypotension, hyperkalemia, and hyperglycemia are not commonly associated with darbepoetin alfa therapy in chronic kidney disease.
3. Escitalopram is prescribed for a 16-year-old adolescent client who is clinically depressed. Five days later, the parent tells the practical nurse (PN) that the drug is not working because their child is not feeling any better. Which explanation should the PN provide?
- A. It takes 1 to 4 weeks for antidepressant medications to become effective.
- B. The dosage may need to be increased; I will contact your health care provider.
- C. Depression is difficult to treat with drugs alone. Therapy sessions would enhance their effectiveness.
- D. Based on your child's response to this drug, the health care provider is reviewing your medication regimen.
Correct answer: A
Rationale: Antidepressant medications typically require 1 to 4 weeks to reach their full therapeutic effect. It is crucial to educate the family that during the initial week of treatment, the child may experience heightened anxiety. Therefore, it is important to wait for the medication to take its full course before assessing its effectiveness.
4. A client with a history of atrial fibrillation is prescribed rivaroxaban. The nurse should monitor for which potential side effect?
- A. Weight gain
- B. Dry mouth
- C. Dizziness
- D. Headache
Correct answer: A
Rationale: The correct answer is weight gain. Rivaroxaban, an anticoagulant, may lead to weight gain as a side effect due to fluid retention. Dry mouth (choice B), dizziness (choice C), and headache (choice D) are not typically associated with rivaroxaban use. Therefore, monitoring for weight gain is crucial to detect and manage this potential side effect in the client.
5. A client who is prescribed sildenafil for pulmonary hypertension calls the clinic for advice. Which condition should the practical nurse notify the health care provider immediately and instruct the client to stop taking the medication?
- A. The client is experiencing vision and hearing loss.
- B. The client has an erection lasting longer than 4 hours.
- C. The client is complaining of nasal congestion.
- D. The client is complaining of feeling flushed.
Correct answer: A
Rationale: The correct answer is A. If a client prescribed sildenafil for pulmonary hypertension experiences vision and/or hearing loss or an erection lasting more than 4 hours, the practical nurse should instruct the client to discontinue the medication immediately and notify the health care provider. These symptoms could indicate serious side effects that require prompt medical attention to prevent complications. Choices B, C, and D are incorrect because an erection lasting more than 2 hours (not 4 hours as stated in choice B) is a critical adverse effect that warrants immediate medical attention. Nasal congestion (choice C) and feeling flushed (choice D) are common side effects of sildenafil and typically do not necessitate immediate discontinuation of the medication or emergency intervention.
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