Nursing Elites

1. What is a causative factor of Hirschsprung disease?

• A. Frequent evacuation of solids, liquids, and gases
• B. Excessive peristaltic movement
• C. Absence of parasympathetic ganglion cells in a portion of the colon
• D. One portion of the bowel telescoping into another

Correct answer: C

Rationale: The correct answer is C: Absence of parasympathetic ganglion cells in a portion of the colon. Hirschsprung disease is a congenital condition characterized by the absence of nerve cells (ganglia) in parts of the colon. This absence leads to a lack of peristalsis in the affected segment, resulting in severe constipation and bowel obstruction. Choices A, B, and D are incorrect. Choice A describes symptoms of diarrhea rather than a causative factor of Hirschsprung disease. Excessive peristaltic movement (choice B) is not a causative factor but rather the opposite, as Hirschsprung disease is associated with reduced peristalsis. Choice D, which refers to intussusception, is a different condition unrelated to Hirschsprung disease.

2. What is the most effective therapy for maintaining remission of acute lymphoblastic leukemia?

• A. Surgery to remove enlarged lymph nodes
• B. Long-term chemotherapy
• C. Nutritional supplements to enhance blood cell production
• D. Blood transfusions to replace ineffective red cells

Correct answer: B

Rationale: The correct answer is B: Long-term chemotherapy. Long-term chemotherapy, specifically with methotrexate, is the most effective therapy for maintaining remission in acute lymphoblastic leukemia. Surgery to remove enlarged lymph nodes (Choice A) is not the primary treatment for leukemia. Nutritional supplements (Choice C) may support overall health but are not the mainstay therapy for maintaining leukemia remission. Blood transfusions (Choice D) are used to address anemia in some cases but are not the primary treatment for maintaining remission in acute lymphoblastic leukemia.

3. What is the primary purpose of a placebo in an experiment?

• A. To reduce the cost of the experiment.
• B. To make the experiment double-blind.
• C. To increase the number of participants.
• D. To serve as a control for comparison with the treatment group.

Correct answer: D

Rationale: The correct answer is D. A placebo serves as a control for comparison with the treatment group, helping to eliminate bias and ensure the results are due to the treatment itself. Placebos are crucial in research to distinguish the actual effect of the treatment from psychological or subjective factors. Choice A is incorrect because the purpose of a placebo is not related to reducing the cost of the experiment. Choice B is incorrect because while placebos are used in double-blind studies, their primary purpose is not to make the experiment double-blind. Choice C is incorrect because the purpose of a placebo is not to increase the number of participants but rather to serve as a comparison group for the treatment being tested.

4. What is an important consideration when administering medications to a child with hepatic dysfunction?

• A. Increased dosing intervals
• B. Adjustments in dosage due to altered metabolism
• C. Avoid all medications
• D. Use only topical medications

Correct answer: B

Rationale: When administering medications to a child with hepatic dysfunction, it is crucial to make adjustments in dosage due to altered metabolism. Hepatic dysfunction can affect the way medications are metabolized in the body, potentially leading to drug toxicity or reduced effectiveness. This is why adjusting the dosage is essential to ensure the medication is both safe and efficient. Choices A, C, and D are incorrect because increasing dosing intervals, avoiding all medications, or using only topical medications do not address the specific issue of altered drug metabolism in hepatic dysfunction.

5. What does the term 'essential nutrient' refer to?

• A. A nutrient that can be synthesized by the body.
• B. A nutrient that is required for proper body functioning.
• C. A nutrient that must be obtained from the diet because the body cannot produce it.
• D. A nutrient that can be stored in the body for long periods.

Correct answer: C

Rationale: The correct answer is C. An essential nutrient is a substance that is necessary for normal body functioning but cannot be synthesized in adequate amounts by the body, therefore it must be obtained from the diet. Choices A, B, and D are incorrect because essential nutrients are not synthesized by the body, they are necessary for body functioning, and they are not typically stored in the body for long periods.

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