what is a causative factor of hirschsprung disease
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HESI PN Nutrition Practice Exam

1. What is a causative factor of Hirschsprung disease?

Correct answer: C

Rationale: The correct answer is C: Absence of parasympathetic ganglion cells in a portion of the colon. Hirschsprung disease is a congenital condition characterized by the absence of nerve cells (ganglia) in parts of the colon. This absence leads to a lack of peristalsis in the affected segment, resulting in severe constipation and bowel obstruction. Choices A, B, and D are incorrect. Choice A describes symptoms of diarrhea rather than a causative factor of Hirschsprung disease. Excessive peristaltic movement (choice B) is not a causative factor but rather the opposite, as Hirschsprung disease is associated with reduced peristalsis. Choice D, which refers to intussusception, is a different condition unrelated to Hirschsprung disease.

2. What will the treatment for a newly admitted child with cystic fibrosis center on?

Correct answer: A

Rationale: The correct answer is A: Chest physiotherapy. Treatment for cystic fibrosis focuses on chest physiotherapy and aerosol medications to manage and clear thick pulmonary secretions. Chest physiotherapy helps loosen and clear mucus from the lungs, aiding in breathing and reducing the risk of infections. Mucus-drying agents (choice B) are not typically used in the treatment of cystic fibrosis as the goal is to help clear mucus, not dry it. Prevention of diarrhea (choice C) is not a primary focus in the treatment of cystic fibrosis. Insulin therapy (choice D) is not relevant to cystic fibrosis, which primarily affects the respiratory and digestive systems.

3. How is gastroesophageal reflux (GER) typically treated in infants?

Correct answer: B

Rationale: Thickening the formula or breast milk with cereal is a common treatment for gastroesophageal reflux (GER) in infants. By adding cereal, the feedings become heavier, making it less likely for the stomach contents to reflux. Keeping the infant NPO (nothing by mouth) is not typically necessary for GER treatment and might not be appropriate. Placing the infant to sleep on the side is not recommended due to the risk of sudden infant death syndrome (SIDS). Switching the infant to cow's milk is also not a recommended treatment for GER as it can exacerbate symptoms due to its protein content.

4. What is the study of how a person's genes interact with nutrients?

Correct answer: B

Rationale: Nutritional genomics, the correct answer, specifically focuses on how a person's genes interact with nutrients, affecting health and disease. Genetic counseling (choice A) refers to the process of helping people understand and adapt to the medical, psychological, and familial implications of genetic contributions to disease. Genetic metabolomics (choice C) combines genetic and metabolomic data to study metabolic pathways. Nutritional genetics (choice D) generally refers to the broader field of genetics as it relates to nutrition, while nutritional genomics, the most precise term, delves into the specific gene-nutrient interactions.

5. If a group of people consumes an amount of protein equal to the estimated average requirement for their population group, what percentage of people will receive insufficient amounts?

Correct answer: D

Rationale: If a group consumes an amount of protein equal to the estimated average requirement, 50% of the people will receive insufficient amounts. The estimated average requirement is the amount of a nutrient that is estimated to meet the requirement of half the healthy individuals in a particular life stage and gender group. Therefore, 50% of the group will not be meeting their individual needs if they are consuming only the average requirement. Choices A, B, and C are incorrect because at the estimated average requirement level, a higher percentage than those values will receive insufficient amounts.

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