HESI LPN
HESI Practice Test Pharmacology
1. A client prescribed glipizide asked why they had to take their insulin orally. How should the practical nurse respond?
- A. Glipizide is not an oral form of insulin and can be used only when some beta cell function is present.
- B. Glipizide is an oral form of insulin and is distributed, metabolized, and excreted in the same manner as insulin.
- C. Glipizide is an oral form of insulin and has the same actions and properties as intermediate insulin.
- D. Glipizide is not an oral form of insulin, but it is effective for those who are resistant to injectable insulins.
Correct answer: A
Rationale: The practical nurse should explain to the client that glipizide is not an oral form of insulin but an oral hypoglycemic agent. Glipizide works by enhancing pancreatic production of insulin when some beta cell function is present. It is not a replacement for insulin but helps the body produce more insulin. Therefore, it can be used when there is still some beta cell function present, unlike insulin which is used when there is a deficiency of endogenous insulin production.
2. What action should the nurse implement for a female client taking the bisphosphonate medication ibandronate for osteoporosis?
- A. Ask the client to describe how she takes the medication
- B. Reassure the client that the heartburn is temporary
- C. Explain that the use of antacids might be helpful
- D. Encourage the client to increase her calcium intake
Correct answer: A
Rationale: Ensuring correct administration of bisphosphonates, like ibandronate, is essential to maximize effectiveness and minimize potential side effects. By asking the client to describe how she takes the medication, the nurse can assess the client's understanding and adherence to the prescribed regimen, ultimately promoting optimal therapeutic outcomes.
3. A client has been prescribed losartan. Which change in data indicates to the practical nurse (PN) that the desired effect of this medication has been achieved?
- A. Dependent edema reduced from +3 to +1.
- B. Serum HDL increased from 35 to 55 mg/dL.
- C. Pulse rate reduced from 150 to 90 beats/min.
- D. Blood pressure reduced from 160/90 to 130/80 mm Hg.
Correct answer: D
Rationale: The correct answer is D. Losartan is prescribed for the treatment of hypertension. The desired effect of losartan is to reduce blood pressure. Therefore, a reduction in blood pressure from 160/90 to 130/80 mm Hg indicates that the desired effect of the medication has been achieved. Choices A, B, and C are not specific effects of losartan and do not directly relate to the expected outcomes of this medication. Dependent edema, serum HDL levels, and pulse rate are not typically influenced by losartan, making choices A, B, and C incorrect.
4. A client with a diagnosis of bipolar disorder is prescribed valproate. The nurse should monitor for which potential adverse effect?
- A. Weight gain
- B. Hair loss
- C. Hyperglycemia
- D. Hypoglycemia
Correct answer: A
Rationale: The correct answer is A: Weight gain. Valproate is known to cause weight gain as a common adverse effect. It is important for the nurse to monitor the client's weight regularly while on this medication to detect and address any changes that may occur.
5. A client with hypertension is prescribed doxazosin. The nurse should monitor for which potential side effect?
- A. Hypotension
- B. Hypertension
- C. Hyperglycemia
- D. Hypernatremia
Correct answer: A
Rationale: The correct answer is A: Hypotension. Doxazosin is an alpha-blocker medication commonly used to treat hypertension. One of the potential side effects of doxazosin is causing a sudden drop in blood pressure, leading to hypotension. Therefore, the nurse should closely monitor the client for signs and symptoms of low blood pressure when initiating or adjusting the dose of doxazosin.
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