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1. Which of the following statements is a symptom of cystic fibrosis in children?
- A. Cystic fibrosis leads to uncontrollable muscle movements and personality changes.
- B. Cystic fibrosis leads to the excessive production of thick mucus that clogs the pancreas and lungs.
- C. Cystic fibrosis causes red blood cells to clump together, obstructing small blood vessels and decreasing the oxygen supply.
- D. Cystic fibrosis causes the central nervous system to degenerate, resulting in death.
Correct answer: B
Rationale: The correct answer is B. Cystic fibrosis is a genetic disorder that causes the body to produce thick, sticky mucus. This mucus can clog the airways in the lungs and obstruct the pancreas, leading to severe respiratory and digestive problems. Choice A is incorrect because uncontrollable muscle movements and personality changes are not typical symptoms of cystic fibrosis. Choice C is incorrect because cystic fibrosis does not directly cause red blood cells to clump together and obstruct small blood vessels. Choice D is incorrect because cystic fibrosis primarily affects the respiratory and digestive systems, not the central nervous system.
2. Which of the following statements is true of Down’s syndrome?
- A. Down’s syndrome is usually caused by an extra copy of chromosome 21 in an individual.
- B. The symptoms of Down’s syndrome are similar to those of sickle-cell anemia.
- C. Down’s syndrome is caused by a sexually transmitted infection (STI) during conception.
- D. The probability of having a child with Down’s syndrome increases with the age of the parents.
Correct answer: D
Rationale: The correct answer is D. The likelihood of having a child with Down’s syndrome increases as the age of the parents increases, particularly the mother's age. Choice A is incorrect because Down’s syndrome is caused by an extra copy of chromosome 21, not a defect in the sex chromosomes. Choice B is incorrect as the symptoms of Down’s syndrome and sickle-cell anemia are different. Choice C is also incorrect as Down’s syndrome is not caused by a sexually transmitted infection during conception.
3. Which field of biology studies heredity?
- A. Etiology.
- B. Ecology.
- C. Genetics.
- D. Eugenics.
Correct answer: C
Rationale: Genetics is the branch of biology that focuses on the study of heredity and variation in organisms. Etiology (choice A) deals with the causes of diseases, not heredity. Ecology (choice B) is concerned with the relationships between organisms and their environment, not specifically heredity. Eugenics (choice D) is a controversial field that involves improving the genetic quality of the human population through selective breeding, which is different from the study of heredity itself.
4. Matt is a 36-year-old male. In the past year, he has noticed that his limbs sometimes move on their own, and he has also started having trouble remembering things and doing simple calculations. Matt’s father and grandfather were also known to have similar problems during their adulthood. Matt is most likely suffering from:
- A. Phenylketonuria (PKU).
- B. Cystic fibrosis.
- C. Turner syndrome.
- D. Huntington’s disease (HD).
Correct answer: D
Rationale: Matt is exhibiting symptoms typical of Huntington’s disease (HD), a hereditary condition characterized by involuntary movements, cognitive impairment, and behavioral changes. The fact that Matt's father and grandfather had similar issues supports the genetic nature of the disease. Phenylketonuria (PKU) is a metabolic disorder that affects amino acid metabolism, not presenting with the symptoms described. Cystic fibrosis primarily affects the respiratory and digestive systems, not causing the neurological symptoms described. Turner syndrome is a genetic condition affecting females and is not associated with the symptoms described in the case of Matt.
5. During which of the following periods does the development of arms and legs occur in a pregnancy?
- A. Development of the lungs
- B. Development of the heart
- C. Development of arms and legs
- D. Development of the stomach
Correct answer: C
Rationale: The correct answer is C. The development of arms and legs occurs during the critical period of the fourth to eighth weeks of pregnancy. This timeframe is crucial for the formation of limbs and other key body parts. Choices A, B, and D are incorrect because the development of the lungs, heart, and stomach respectively occurs at different stages of fetal development and is not primarily associated with the fourth to eighth weeks of pregnancy.
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