HESI LPN
HESI Practice Test Pharmacology
1. A client with a history of stroke is prescribed clopidogrel. The nurse should monitor for which potential side effect?
- A. Bleeding
- B. Weight gain
- C. Nausea
- D. Headache
Correct answer: A
Rationale: When a client with a history of stroke is prescribed clopidogrel, the nurse should monitor for potential side effects, especially bleeding. Clopidogrel is an antiplatelet medication that works by preventing blood clots. One of the major risks associated with clopidogrel is an increased tendency to bleed. Therefore, monitoring for signs of bleeding, such as easy bruising, blood in stool or urine, or prolonged bleeding from minor cuts, is crucial to ensure patient safety and early intervention if needed.
2. A client is receiving heparin to treat a deep vein thrombosis. The nurse should monitor which laboratory result to assist in evaluating the efficacy of the drug?
- A. Platelet count
- B. Prothrombin time
- C. Partial thromboplastin time
- D. Serum levels of protamine sulfate
Correct answer: C
Rationale: The nurse should monitor the partial thromboplastin time to evaluate the efficacy of heparin. Partial thromboplastin time reflects the anticoagulant effect of heparin by measuring the intrinsic pathway of coagulation. Platelet count assesses platelet levels and is not specific to heparin efficacy. Prothrombin time is used to monitor warfarin therapy. Serum levels of protamine sulfate are not used to evaluate the efficacy of heparin.
3. A client with osteoporosis is prescribed alendronate. The practical nurse (PN) should reinforce which instruction regarding the administration of this medication?
- A. Take the medication with a full glass of water before breakfast.
- B. Take the medication immediately after a meal.
- C. Lie down for 30 minutes after taking the medication.
- D. Crush the medication and mix it with food.
Correct answer: A
Rationale: The correct instruction for administering alendronate is to take the medication with a full glass of water before breakfast. This timing is crucial to ensure proper absorption in the body and reduce the risk of esophageal irritation. Taking it immediately after a meal or lying down for 30 minutes after may affect absorption and increase the risk of adverse effects. It should not be crushed or mixed with food to maintain its effectiveness.
4. When administering medications to a group of clients, which client should the nurse closely monitor for the development of acute kidney injury (AKI)?
- A. Lorazepam
- B. Sucralfate
- C. Digoxin
- D. Vancomycin
Correct answer: D
Rationale: Vancomycin is known to be nephrotoxic, which means it can cause damage to the kidneys. Therefore, clients receiving Vancomycin should be closely monitored for signs and symptoms of acute kidney injury (AKI) to ensure early detection and intervention if necessary. Lorazepam, Sucralfate, and Digoxin do not typically cause acute kidney injury, so they are not the priority for monitoring in this scenario.
5. A patient is prescribed sucralfate (Carafate) and asks the nurse what the purpose of taking this medication is. Which is the nurse's best response?
- A. The medication helps reduce bacteria levels in the stomach
- B. The medication helps neutralize gastric acid in the stomach
- C. The medication is used to protect the gastrointestinal mucosa
- D. The medication can reduce the patient's constipation
Correct answer: C
Rationale: The correct answer is C. Sucralfate (Carafate) is used to protect the gastrointestinal mucosa by forming a protective barrier over ulcers. This barrier helps prevent stomach acid from further damaging the ulcers and promotes healing. It does not directly reduce bacteria levels, neutralize gastric acid, or have a direct effect on constipation.
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