HESI RN
Biology Practice Test
1. During which stage of mitosis do the chromosomes gather on either side of the separating cell?
- A. Metaphase
- B. Telophase
- C. Anaphase
- D. Prophase
Correct answer: B
Rationale: The correct answer is B, Telophase. During telophase, the chromosomes gather at opposite poles of the cell as the nuclear envelopes start to form around them, indicating the end of cell division. Choices A, C, and D are incorrect because during metaphase, the chromosomes align in the middle of the cell; in anaphase, the chromosomes separate and move towards opposite poles; and in prophase, the chromosomes condense and the nuclear envelope breaks down, respectively.
2. At the beginning of meiosis, how many chromosomes does the diploid parent cell have?
- A. 23
- B. 24
- C. 46
- D. 54
Correct answer: C
Rationale: The correct answer is C: 46. At the start of meiosis, the diploid parent cell contains 46 chromosomes. During meiosis, the number of chromosomes is halved, resulting in each gamete having 23 chromosomes. Choice A (23) is incorrect because that is the number of chromosomes in a human gamete, not the parent cell. Choice B (24) and Choice D (54) are also incorrect as they do not reflect the correct number of chromosomes in a diploid parent cell at the beginning of meiosis.
3. In the hierarchy of biology, cells combine to form which of the following?
- A. Macromolecules
- B. Molecules
- C. Tissues
- D. Organelles
Correct answer: C
Rationale: In the hierarchy of biology, cells combine to form tissues. Tissues are groups of cells that work together to perform specific functions. This is a fundamental level of organization above individual cells but below organs and organ systems. Macromolecules and molecules are smaller components that make up cells, not what cells combine to form. Organelles are structures within cells that perform specific functions and do not result from the combination of cells.
4. Which of the following is a group of three RNA nucleotides?
- A. A stop codon
- B. A codon
- C. An anticodon
- D. tRNA
Correct answer: B
Rationale: The correct answer is B - A codon. A codon is a sequence of three RNA nucleotides that specifies a particular amino acid or a stop signal during protein synthesis. Choice A, a stop codon, is a sequence of three nucleotides that signals the termination of protein synthesis. Choice C, an anticodon, is a group of three nucleotides found in tRNA that pairs with the complementary codon in mRNA. Choice D, tRNA, stands for transfer RNA, which is a type of RNA that carries amino acids to the ribosome during protein synthesis.
5. Which of the following molecules acts as the genetic code's messenger?
- A. RNA
- B. Proteins
- C. DNA
- D. Carbohydrates
Correct answer: A
Rationale: The correct answer is RNA. RNA, particularly mRNA, serves as the messenger that carries genetic information from DNA to the ribosome, where proteins are synthesized. Proteins (choice B) are not the genetic code's messenger; they are synthesized based on the information carried by RNA. DNA (choice C) stores the genetic information but does not directly act as the messenger. Carbohydrates (choice D) are not involved in transmitting genetic information.
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