HESI RN
Biology Practice Test
1. Water is held together by which of the following bonds?
- A. Electrostatic attraction
- B. Van der Waals forces
- C. Hydrogen
- D. Oxygen
Correct answer: C
Rationale: Water molecules are held together by hydrogen bonds, which are weak bonds formed between the slightly positive hydrogen atom of one water molecule and the slightly negative oxygen atom of another. Choice A, electrostatic attraction, is a general term for the attraction between opposite charges but does not specifically describe the bonds in water. Choice B, Van der Waals forces, are weak intermolecular forces that arise from temporary fluctuations in electron distribution, not the primary bonds in water. Choice D, oxygen, is incorrect as oxygen is part of the water molecule but not the bond holding water molecules together.
2. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?
- A. They are gathered on either side of the separating cell
- B. They are all aligned along the metaphase plate
- C. They are attached to the spindle
- D. They are visibly separate
Correct answer: D
Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.
3. Which of the following statements is most accurate regarding the transcription of DNA?
- A. RNA uses reverse transcriptase to make mRNA
- B. DNA uses mRNA to produce tRNA
- C. RNA creates a duplicate copy of DNA
- D. RNA copies DNA to produce mRNA
Correct answer: D
Rationale: The correct answer is D. During transcription, RNA copies DNA to produce mRNA, which carries the genetic information from DNA to the ribosomes for protein synthesis. Choice A is incorrect because reverse transcriptase is not involved in the transcription of DNA. Choice B is incorrect as DNA does not use mRNA to produce tRNA; tRNA is produced through a different process. Choice C is incorrect as RNA does not create a duplicate copy of DNA during transcription; it synthesizes mRNA by copying the DNA template.
4. Which of the following makes it possible to predict the genotype and phenotype of the offspring of sexual reproduction?
- A. Punnett square
- B. Chi-square
- C. Microscope
- D. None of these
Correct answer: A
Rationale: The correct answer is A, Punnett square. A Punnett square is a tool specifically designed to predict the genotype and phenotype combinations of offspring resulting from a particular cross or breeding experiment. It helps in understanding the probability of different genotypes and phenotypes appearing in the offspring. Choice B, Chi-square, is a statistical test used to determine if there is a significant difference between the expected frequencies and the observed frequencies in a study. Choice C, Microscope, is used for viewing tiny structures and organisms, not for predicting genetic outcomes. Choice D, None of these, is incorrect as Punnett square is a valid tool for predicting genetic outcomes in offspring.
5. Phagocytes in the immune system are responsible for the biological action of which of the following?
- A. Secreting
- B. Consuming
- C. Altering
- D. Building
Correct answer: B
Rationale: The correct answer is B: Consuming. Phagocytes are cells that engulf and digest pathogens, dead cells, and other harmful particles, playing a crucial role in the immune system's defense. Phagocytes do not secrete substances, alter particles, or build structures; their primary function is to consume and eliminate harmful entities.
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