HESI RN

1. Protein synthesis begins with a process known as transcription. Where does this process occur?

• A. In the cytoplasm
• B. In the nuclear envelope
• C. In the ribosome unit
• D. In the nucleus

Correct Answer: D

Rationale: The correct answer is D: In the nucleus. Transcription, the initial step of protein synthesis, takes place in the nucleus where DNA is transcribed into mRNA. This mRNA then leaves the nucleus and enters the cytoplasm where translation occurs on the ribosomes. Choices A, B, and C are incorrect because transcription specifically occurs in the nucleus, not in the cytoplasm, nuclear envelope, or ribosome unit.

2. What is the main objective of the translation stage of protein synthesis?

• A. To produce amino acids
• B. To produce nucleotides
• C. To produce fatty acids
• D. To produce proteins

Correct Answer: D

Rationale: The main objective of the translation stage of protein synthesis is to produce proteins. During translation, ribosomes decode mRNA sequences to synthesize proteins by linking amino acids together. Choice A, 'To produce amino acids,' is incorrect as amino acids are the building blocks of proteins and are not produced during translation. Choices B and C, 'To produce nucleotides' and 'To produce fatty acids,' are also incorrect as these molecules are not the direct products of the translation stage of protein synthesis.

3. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?

• A. They are gathered on either side of the separating cell
• B. They are all aligned along the metaphase plate
• C. They are attached to the spindle
• D. They are visibly separate

Correct Answer: D

Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.

4. In which step of cellular respiration is the most adenosine triphosphate (ATP) created?

• A. Electron transport chain
• B. Glycolysis
• C. Citric acid cycle (the Krebs cycle)
• D. All of these produce equal amounts of ATP

Correct Answer: A

Rationale: The electron transport chain is the step in cellular respiration that generates the most ATP. During this step, up to 34 ATP molecules can be produced from a single glucose molecule. Choice B, Glycolysis, produces a smaller amount of ATP (2 ATP molecules per glucose), and choice C, Citric acid cycle, produces some ATP but not as much as the electron transport chain. Choice D is incorrect because different steps of cellular respiration produce varying amounts of ATP, with the electron transport chain being the most efficient in ATP generation.

5. Which of the following provides support and shape to the cell?

• A. Microtubules
• B. Microfilaments
• C. Cilia
• D. Microvilli

Correct Answer: A

Rationale: Microtubules are fundamental components of the cytoskeleton in a cell, playing a crucial role in providing structural support and maintaining the cell's shape. They are composed of tubulin protein subunits and are involved in various cellular processes like cell division, intracellular transport, and cell motility. Microfilaments, on the other hand, are involved in cell movement and maintaining cell shape but are not primarily responsible for supporting the cell's overall structure. Cilia and microvilli are cellular projections that aid in movement and absorption, respectively, but they do not play a significant role in providing structural support to the cell.