HESI RN
Biology Practice Test
1. The bilayer of the cellular membrane consists of phospholipids with all except which of the following scattered throughout?
- A. Nucleic acids
- B. Cholesterol
- C. Proteins
- D. Glycoproteins
Correct answer: A
Rationale: The cellular membrane is composed of a phospholipid bilayer with cholesterol, proteins, and glycoproteins distributed throughout. Nucleic acids are not found within the cellular membrane. Cholesterol helps maintain membrane fluidity, while proteins and glycoproteins play important roles in cell signaling, transport, and structural support.
2. Which of the following options is the term used to represent alternative versions of a gene?
- A. Alleles
- B. Binary fission
- C. Heterozygous
- D. Homozygous
Correct answer: A
Rationale: The correct answer is A: Alleles. Alleles are different forms of a gene that can exist at a specific locus on a chromosome. They represent variations in a gene's DNA sequence. Choices B, C, and D are incorrect. Binary fission is a form of asexual reproduction in single-celled organisms, while heterozygous and homozygous refer to different combinations of alleles in an individual, not the alternative versions of a gene.
3. Which of the following is a group of three RNA nucleotides?
- A. A stop codon
- B. A codon
- C. An anticodon
- D. tRNA
Correct answer: B
Rationale: The correct answer is B - A codon. A codon is a sequence of three RNA nucleotides that specifies a particular amino acid or a stop signal during protein synthesis. Choice A, a stop codon, is a sequence of three nucleotides that signals the termination of protein synthesis. Choice C, an anticodon, is a group of three nucleotides found in tRNA that pairs with the complementary codon in mRNA. Choice D, tRNA, stands for transfer RNA, which is a type of RNA that carries amino acids to the ribosome during protein synthesis.
4. What is located on the rough endoplasmic reticulum?
- A. Microvilli
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: D
Rationale: The rough endoplasmic reticulum is studded with ribosomes, which are responsible for protein synthesis. Ribosomes are the correct answer because they are the organelles directly associated with the rough endoplasmic reticulum. Microvilli (choice A), mitochondria (choice B), and lysosomes (choice C) are not typically located on the rough endoplasmic reticulum. Microvilli are found on the surface of cells to increase surface area, mitochondria are the powerhouses of the cell responsible for energy production, and lysosomes are membrane-bound organelles containing digestive enzymes.
5. What is the main objective of the translation stage of protein synthesis?
- A. To produce amino acids
- B. To produce nucleotides
- C. To produce fatty acids
- D. To produce proteins
Correct answer: D
Rationale: The main objective of the translation stage of protein synthesis is to produce proteins. During translation, ribosomes decode mRNA sequences to synthesize proteins by linking amino acids together. Choice A, 'To produce amino acids,' is incorrect as amino acids are the building blocks of proteins and are not produced during translation. Choices B and C, 'To produce nucleotides' and 'To produce fatty acids,' are also incorrect as these molecules are not the direct products of the translation stage of protein synthesis.
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