HESI RN
Biology Practice Test
1. The bilayer of the cellular membrane consists of phospholipids with all except which of the following scattered throughout?
- A. Nucleic acids
- B. Cholesterol
- C. Proteins
- D. Glycoproteins
Correct answer: A
Rationale: The cellular membrane is composed of a phospholipid bilayer with cholesterol, proteins, and glycoproteins distributed throughout. Nucleic acids are not found within the cellular membrane. Cholesterol helps maintain membrane fluidity, while proteins and glycoproteins play important roles in cell signaling, transport, and structural support.
2. The Punnett square shows that one parent carries the recessive gene for a cleft chin (c) while the other parent does not. What percentage of the parents' offspring is predicted to have a cleft chin?
- A. 25%
- B. 50%
- C. 0%
- D. 75%
Correct answer: C
Rationale: The correct answer is 0%. If one parent carries the recessive gene for a cleft chin while the other parent does not, none of the offspring will express the recessive phenotype. This is because in order for a child to have a cleft chin, they would need to inherit the recessive gene from both parents. Therefore, although the offspring could be carriers of the gene, none are predicted to have a cleft chin. Choices A, B, and D are incorrect because the presence of the recessive gene in one parent and its absence in the other would not result in any offspring showing the cleft chin trait.
3. In meiosis, the chromosome number is reduced from:
- A. 46 to 23
- B. 46 to 33
- C. 28 to 14
- D. 24 to 12
Correct answer: A
Rationale: The correct answer is A: "46 to 23." In meiosis, the chromosome number is reduced by half to form gametes for sexual reproduction. In humans, where the diploid chromosome number is 46, meiosis results in haploid cells with 23 chromosomes. Choices B, C, and D are incorrect because they do not represent the correct reduction in chromosome number during meiosis.
4. Protein synthesis begins with a process known as transcription. Where does this process occur?
- A. In the cytoplasm
- B. In the nuclear envelope
- C. In the ribosome unit
- D. In the nucleus
Correct answer: D
Rationale: The correct answer is D: In the nucleus. Transcription, the initial step of protein synthesis, takes place in the nucleus where DNA is transcribed into mRNA. This mRNA then leaves the nucleus and enters the cytoplasm where translation occurs on the ribosomes. Choices A, B, and C are incorrect because transcription specifically occurs in the nucleus, not in the cytoplasm, nuclear envelope, or ribosome unit.
5. Water is held together by which of the following bonds?
- A. Electrostatic attraction
- B. Van der Waals forces
- C. Hydrogen
- D. Oxygen
Correct answer: C
Rationale: Water molecules are held together by hydrogen bonds, which are weak bonds formed between the slightly positive hydrogen atom of one water molecule and the slightly negative oxygen atom of another. Choice A, electrostatic attraction, is a general term for the attraction between opposite charges but does not specifically describe the bonds in water. Choice B, Van der Waals forces, are weak intermolecular forces that arise from temporary fluctuations in electron distribution, not the primary bonds in water. Choice D, oxygen, is incorrect as oxygen is part of the water molecule but not the bond holding water molecules together.
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