HESI RN
Biology Practice Test
1. The bilayer of the cellular membrane consists of phospholipids with all except which of the following scattered throughout?
- A. Nucleic acids
- B. Cholesterol
- C. Proteins
- D. Glycoproteins
Correct answer: A
Rationale: The cellular membrane is composed of a phospholipid bilayer with cholesterol, proteins, and glycoproteins distributed throughout. Nucleic acids are not found within the cellular membrane. Cholesterol helps maintain membrane fluidity, while proteins and glycoproteins play important roles in cell signaling, transport, and structural support.
2. During which stage of mitosis do the chromosomes gather on either side of the separating cell?
- A. Metaphase
- B. Telophase
- C. Anaphase
- D. Prophase
Correct answer: B
Rationale: The correct answer is B, Telophase. During telophase, the chromosomes gather at opposite poles of the cell as the nuclear envelopes start to form around them, indicating the end of cell division. Choices A, C, and D are incorrect because during metaphase, the chromosomes align in the middle of the cell; in anaphase, the chromosomes separate and move towards opposite poles; and in prophase, the chromosomes condense and the nuclear envelope breaks down, respectively.
3. Which of the following is responsible for the synthesis of carbohydrates, lipids, and steroid hormones?
- A. Smooth endoplasmic reticulum (ER)
- B. Rough endoplasmic reticulum (ER)
- C. Golgi apparatus
- D. Ribosomes
Correct answer: A
Rationale: The smooth endoplasmic reticulum (ER) is the correct answer. It is responsible for the synthesis of lipids, including steroids, and also plays a role in carbohydrate metabolism. The rough endoplasmic reticulum (ER) is involved in protein synthesis and processing, not lipid or carbohydrate synthesis. The Golgi apparatus is responsible for modifying, sorting, and packaging of proteins and lipids, but not for their synthesis. Ribosomes are the cellular organelles responsible for protein synthesis, not lipid or carbohydrate synthesis.
4. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?
- A. They are gathered on either side of the separating cell
- B. They are all aligned along the metaphase plate
- C. They are attached to the spindle
- D. They are visibly separate
Correct answer: D
Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.
5. Who discovered the basic principles of genetics using garden peas?
- A. Curie
- B. Mendel
- C. Hawking
- D. Galileo
Correct answer: B
Rationale: The correct answer is B, Mendel. Gregor Mendel is known as the father of genetics for his groundbreaking work with pea plants. He discovered the basic principles of heredity through his experiments, establishing the foundation of modern genetics. Choice A, Curie, is incorrect as Marie Curie was a physicist and chemist known for her pioneering research on radioactivity. Choice C, Hawking, is incorrect as Stephen Hawking was a theoretical physicist known for his work on black holes and cosmology. Choice D, Galileo, is incorrect as Galileo Galilei was an astronomer and physicist renowned for his contributions to the scientific revolution, particularly in astronomy.
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