HESI RN
Biology Test
1. What do prokaryotic cells lack in comparison to eukaryotic cells?
- A. A defined nucleus and a series of membrane-bound organelles
- B. A defined nucleus and no membrane-bound organelles
- C. No defined nucleus and a series of membrane-bound organelles
- D. No defined nucleus and no membrane-bound organelles
Correct answer: D
Rationale: Prokaryotic cells are characterized by the absence of a defined nucleus and membrane-bound organelles. Choice A is incorrect because prokaryotic cells lack membrane-bound organelles. Choice B is incorrect because prokaryotic cells lack both a defined nucleus and membrane-bound organelles. Choice C is incorrect as prokaryotic cells have no defined nucleus. Therefore, the correct answer is D.
2. During which stage of mitosis does the nuclear envelope begin to disappear and the chromosomes start attaching to the spindle forming along the cell's axis?
- A. Prometaphase
- B. Metaphase
- C. Anaphase
- D. Prophase
Correct answer: A
Rationale: The correct answer is A, Prometaphase. During prometaphase, the nuclear envelope disintegrates, and chromosomes start attaching to spindle fibers. In metaphase, chromosomes align in the middle of the cell. Anaphase is characterized by the separation of sister chromatids, and prophase involves the condensation of chromosomes and the beginning of spindle formation.
3. Which of the following is not found in a prokaryotic cell?
- A. Plasma membrane
- B. Cytoplasm
- C. Nucleus
- D. Ribosomes
Correct answer: C
Rationale: The correct answer is C, 'Nucleus.' Prokaryotic cells do not have a defined nucleus, unlike eukaryotic cells. The plasma membrane, cytoplasm, and ribosomes are all components found in prokaryotic cells. The plasma membrane surrounds the cell and regulates what enters and exits, the cytoplasm is the gel-like substance that fills the cell, and ribosomes are responsible for protein synthesis.
4. Which of the following molecules contains the code required for replication?
- A. Deoxyribonucleic acid (DNA)
- B. Transfer RNA (tRNA)
- C. Messenger RNA (mRNA)
- D. Ribonucleic acid (RNA)
Correct answer: A
Rationale: The correct answer is A: Deoxyribonucleic acid (DNA). DNA contains the genetic information essential for replication, ensuring the accurate transmission of genetic material from one generation to the next. Choice B, Transfer RNA (tRNA), is involved in protein synthesis, not replication. Choice C, Messenger RNA (mRNA), carries genetic information from DNA to the ribosome but does not contain the code for replication. Choice D, Ribonucleic acid (RNA), is a broader category that includes both mRNA and tRNA, but the specific molecule containing the code required for replication is DNA.
5. Which organelle is responsible for the synthesis of lipids and steroid hormones?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Golgi apparatus
- D. Ribosomes
Correct answer: B
Rationale: The smooth endoplasmic reticulum is the correct organelle responsible for the synthesis of lipids, including phospholipids, cholesterol, and steroid hormones. The rough endoplasmic reticulum is primarily involved in protein synthesis and processing, making choice A incorrect. The Golgi apparatus is responsible for modifying, sorting, and packaging proteins and lipids for transportation, so it is not directly involved in lipid and steroid hormone synthesis, making choice C incorrect. Ribosomes are responsible for protein synthesis and are not involved in lipid or steroid hormone synthesis, making choice D incorrect.
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