HESI RN
Biology Test
1. Which of the following statements is most accurate regarding the transcription of DNA?
- A. RNA uses reverse transcriptase to make mRNA
- B. DNA uses mRNA to produce tRNA
- C. RNA creates a duplicate copy of DNA
- D. RNA copies DNA to produce mRNA
Correct answer: D
Rationale: The correct answer is D. During transcription, RNA copies DNA to produce mRNA, which carries the genetic information from DNA to the ribosomes for protein synthesis. Choice A is incorrect because reverse transcriptase is not involved in the transcription of DNA. Choice B is incorrect as DNA does not use mRNA to produce tRNA; tRNA is produced through a different process. Choice C is incorrect as RNA does not create a duplicate copy of DNA during transcription; it synthesizes mRNA by copying the DNA template.
2. In meiosis, the chromosome number is reduced from:
- A. 46 to 23
- B. 46 to 33
- C. 28 to 14
- D. 24 to 12
Correct answer: A
Rationale: The correct answer is A: "46 to 23." In meiosis, the chromosome number is reduced by half to form gametes for sexual reproduction. In humans, where the diploid chromosome number is 46, meiosis results in haploid cells with 23 chromosomes. Choices B, C, and D are incorrect because they do not represent the correct reduction in chromosome number during meiosis.
3. Which of the following do prokaryotic cells lack?
- A. A cell membrane
- B. Genetic material
- C. Cytoplasm
- D. Membrane-bound organelles
Correct answer: D
Rationale: The correct answer is D: Prokaryotic cells lack membrane-bound organelles, such as mitochondria or a nucleus, distinguishing them from eukaryotic cells. Prokaryotic cells do have genetic material, a cell membrane, and cytoplasm. Choice A is incorrect because prokaryotic cells do have a cell membrane, which is essential for maintaining cell structure and regulating what enters and exits the cell. Choice B is incorrect because prokaryotic cells contain genetic material, typically in the form of a single circular chromosome. Choice C is incorrect because prokaryotic cells have cytoplasm, where various cellular activities take place.
4. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?
- A. They are gathered on either side of the separating cell
- B. They are all aligned along the metaphase plate
- C. They are attached to the spindle
- D. They are visibly separate
Correct answer: D
Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.
5. What percentage of the parents' offspring is predicted to have a cleft chin if one parent carries the recessive gene for a cleft chin (c) while the other parent does not?
- A. 25%
- B. 50%
- C. 0%
- D. 75%
Correct answer: C
Rationale: The correct answer is C (0%). If one parent carries the recessive gene for a cleft chin while the other parent does not carry it, none of their offspring is predicted to have a cleft chin. This is because the cleft chin trait is recessive, so for an offspring to express this trait, they would need to inherit the gene from both parents. In this scenario, none of the offspring will inherit the recessive gene from both parents, so the percentage of offspring predicted to have a cleft chin is 0%. Choices A, B, and D are incorrect because in this situation, the offspring will not express the cleft chin phenotype, although they could be carriers of the recessive gene.
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