HESI RN
Biology Test
1. What is the smallest and most basic unit of matter?
- A. Micromolecule
- B. Atom
- C. Organelle
- D. Molecule
Correct answer: B
Rationale: The correct answer is B, Atom. An atom is the smallest unit of matter that retains the properties of an element. Choice A, Micromolecule, is incorrect because molecules are composed of atoms bonded together, making them larger than individual atoms. Choice C, Organelle, is incorrect as organelles are structures within cells, not the basic unit of matter. Choice D, Molecule, is incorrect as molecules are made up of atoms bonded together, so they are not the smallest unit of matter.
2. What is the difference between DNA and RNA?
- A. RNA has an extra Phosphate group
- B. DNA has one less oxygen than RNA
- C. RNA has one less oxygen than DNA
- D. DNA has an extra sugar molecule
Correct answer: B
Rationale: The correct answer is B. DNA has one less oxygen atom in its sugar molecule (deoxyribose) compared to RNA, which has a ribose sugar. Choice A is incorrect because RNA does not have an extra phosphate group. Choice C is incorrect as RNA actually has one more oxygen atom than DNA. Choice D is incorrect as DNA and RNA have different sugar molecules, with DNA having deoxyribose and RNA having ribose.
3. Which of the following is the process that reduces cells originally classified as diploid to haploid?
- A. Meiosis
- B. Photosynthesis
- C. Mitosis
- D. Cytokinesis
Correct answer: A
Rationale: The correct answer is A, Meiosis. Meiosis is the cell division process that reduces the chromosome number from diploid to haploid, which is essential for sexual reproduction. Choice B, Photosynthesis, is the process by which green plants and some other organisms use sunlight to synthesize foods with the help of chlorophyll. Choice C, Mitosis, is a cell division process that results in two diploid daughter cells with the same number of chromosomes as the parent cell. Choice D, Cytokinesis, is the division of the cytoplasm following cell division.
4. The bilayer of the cellular membrane consists of phospholipids with all except which of the following scattered throughout?
- A. Nucleic acids
- B. Cholesterol
- C. Proteins
- D. Glycoproteins
Correct answer: A
Rationale: The cellular membrane is composed of a phospholipid bilayer with cholesterol, proteins, and glycoproteins distributed throughout. Nucleic acids are not found within the cellular membrane. Cholesterol helps maintain membrane fluidity, while proteins and glycoproteins play important roles in cell signaling, transport, and structural support.
5. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?
- A. They are gathered on either side of the separating cell
- B. They are all aligned along the metaphase plate
- C. They are attached to the spindle
- D. They are visibly separate
Correct answer: D
Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.
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