Nursing Elites

1. A client with autosomal dominant polycystic kidney disease (ADPKD) asks, “Will my children develop this disease?” How should the nurse respond?

• A. No genetic link is known, so your children are not at increased risk.
• B. Your sons will develop this disease because it has a sex-linked gene.
• C. Only if both you and your spouse are carriers of this disease.
• D. Each of your children has a 50% risk of having ADPKD.

Correct answer: D

Rationale: Children whose parent has the autosomal dominant form of PKD have a 50% chance of inheriting the gene that causes the disease. ADPKD is transmitted as an autosomal dominant trait and therefore is not gender-specific. Both parents do not need to have this disorder. Choice A is incorrect because ADPKD has a known genetic link and a definitive mode of inheritance. Choice B is incorrect as ADPKD is not sex-linked but autosomal dominant. Choice C is incorrect because ADPKD follows an autosomal dominant inheritance pattern and does not require both parents to be carriers for the child to inherit the disease.

2. The healthcare professional is preparing to give a dose of trimethoprim-sulfamethoxazole (TMP-SMX) and learns that the patient takes warfarin (Coumadin). The healthcare professional will request an order for

• A. a decreased dose of TMP-SMX.
• B. a different antibiotic.
• C. an increased dose of warfarin.
• D. coagulation studies.

Correct answer: D

Rationale: Sulfonamides, like trimethoprim-sulfamethoxazole (TMP-SMX), can potentiate the anticoagulant effects of warfarin (Coumadin). To monitor the patient's response and prevent adverse effects, the healthcare professional should request coagulation studies, such as International Normalized Ratio (INR) levels. Choosing a decreased dose of TMP-SMX would not address the potential drug interaction between TMP-SMX and warfarin. Opting for a different antibiotic is not necessary if the interaction can be managed by monitoring. Increasing the dose of warfarin without monitoring could lead to excessive anticoagulation and adverse events, so it's not the appropriate action in this scenario.

3. A patient with a diagnosis of Cushing's syndrome is likely to exhibit which of the following symptoms?

• A. Hyperpigmentation.
• B. Moon face.
• C. Hypotension.
• D. Hypertension.

Correct answer: B

Rationale: The correct answer is B: Moon face. Cushing's syndrome is characterized by excess cortisol levels, leading to the distinctive round and full face known as moon face. Hyperpigmentation (choice A) may occur due to increased ACTH levels, but it is not a hallmark symptom like moon face. Hypotension (choice C) is less common in Cushing's syndrome as cortisol typically leads to hypertension (choice D) due to its effects on blood pressure regulation.

4. A female client taking oral contraceptives reports to the nurse that she is experiencing calf pain. What action should the nurse implement?

• A. Determine if the client has also experienced breast tenderness and weight gain.
• B. Encourage the client to begin a regular, daily program of walking and exercise.
• C. Advise the client to notify the healthcare provider for immediate medical attention.
• D. Tell the client to stop taking the medication for a week to see if symptoms subside.

Correct answer: C

Rationale: Calf pain is indicative of thrombophlebitis, a serious, life-threatening complication associated with the use of oral contraceptives which requires further assessment and possibly immediate medical intervention.

5. What is the primary purpose of administering IV fluids to a patient in septic shock?

• A. To reduce blood pressure.
• B. To increase cardiac output.
• C. To stabilize blood glucose levels.
• D. To maintain adequate tissue perfusion.

Correct answer: D

Rationale: The primary purpose of administering IV fluids to a patient in septic shock is to maintain adequate tissue perfusion. In septic shock, there is a significant drop in blood pressure and systemic vascular resistance leading to poor tissue perfusion. IV fluids help to restore intravascular volume, improve perfusion to vital organs, and prevent organ failure. Choice A ('To reduce blood pressure') is incorrect because IV fluids in septic shock aim to restore tissue perfusion rather than lower blood pressure. Choice B ('To increase cardiac output') is incorrect as the primary goal is to improve tissue perfusion, not specifically increase cardiac output. Choice C ('To stabilize blood glucose levels') is unrelated to the primary purpose of administering IV fluids in septic shock, which is to address the compromised tissue perfusion.

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