Nursing Elites

1. The patient is taking low-dose erythromycin prophylactically and will start cefaclor for treating an acute infection. The nurse should discuss this with the provider because taking both medications simultaneously can cause which effect?

• A. Decreased effectiveness of cefaclor.
• B. Increased effectiveness of cefaclor.
• C. Decreased effectiveness of erythromycin.
• D. Increased effectiveness of erythromycin.

Correct answer: A

Rationale: When erythromycin and cefaclor are taken together, erythromycin can inhibit the metabolism of cefaclor, leading to elevated cefaclor levels and potentially causing adverse effects. This results in a decrease in the effectiveness of cefaclor. Therefore, the nurse should discuss this potential drug interaction with the provider to consider an alternative treatment or adjust the dosages to prevent complications. Choices B, C, and D are incorrect because the concern lies with the effect on cefaclor when combined with erythromycin, not the effect on erythromycin itself.

2. When monitoring a client who is receiving tissue plasminogen activator (t-PA), the nurse should have resuscitation equipment available because reperfusion of the cardiac tissue can result in which of the following?

• A. Cardiac arrhythmias.
• B. Hypertension.
• C. Seizures.
• D. Hypothermia.

Correct answer: A

Rationale: The correct answer is A: Cardiac arrhythmias. Reperfusion of cardiac tissue following t-PA administration can lead to cardiac arrhythmias, necessitating resuscitation equipment. Hypertension (choice B) is a common side effect of t-PA but is not directly related to reperfusion. Seizures (choice C) and hypothermia (choice D) are not typically associated with reperfusion from t-PA administration.

3. A client with chronic renal failure is being treated with sodium polystyrene sulfonate (Kayexalate). The nurse should monitor the client for which of the following?

• A. Hyponatremia.
• B. Hypokalemia.
• C. Hyperkalemia.
• D. Hypocalcemia.

Correct answer: C

Rationale: The correct answer is C: Hyperkalemia. Sodium polystyrene sulfonate (Kayexalate) is used to treat high potassium levels (hyperkalemia) by exchanging sodium ions for potassium ions in the large intestine, which is then eliminated through the feces. Therefore, the nurse should monitor the client for changes in potassium levels to ensure the effectiveness of the treatment. Choices A, B, and D are incorrect because sodium polystyrene sulfonate (Kayexalate) is not associated with causing hyponatremia, hypokalemia, or hypocalcemia.

4. A client with renal insufficiency and a low red blood cell count asks, 'Is my anemia related to the renal insufficiency?' How should the nurse respond?

• A. Red blood cells produce erythropoietin, which increases blood flow to the kidneys.
• B. Your anemia and renal insufficiency are related to inadequate vitamin D and a loss of bone density.
• C. Erythropoietin is usually released from the kidneys and stimulates red blood cell production in the bone marrow.
• D. Kidney insufficiency inhibits active transportation of red blood cells throughout the blood.

Correct answer: C

Rationale: The correct answer is C. Erythropoietin is produced in the kidney and is released in response to decreased oxygen tension in the renal blood supply. Erythropoietin stimulates red blood cell production in the bone marrow. Anemia in renal insufficiency is often due to decreased erythropoietin production. Anemia and renal insufficiency are not manifestations of vitamin D deficiency as stated in choice B. Choice A is incorrect as erythropoietin does not increase blood flow to the kidneys. Choice D is incorrect because kidney insufficiency does not inhibit active transportation of red blood cells throughout the blood; rather, it affects erythropoietin production and subsequent red blood cell formation.

5. A client is receiving a continuous IV infusion of heparin for the treatment of deep vein thrombosis. The client’s activated partial thromboplastin time (aPTT) level is 80 seconds. The client’s baseline before the initiation of therapy was 30 seconds. Which action does the nurse anticipate is needed?

• A. Shutting off the heparin infusion
• B. Increasing the rate of the heparin infusion
• C. Decreasing the rate of the heparin infusion
• D. Leaving the rate of the heparin infusion as is

Correct answer: C

Rationale: The nurse needs to decrease the rate of the heparin infusion. The therapeutic dose of heparin for the treatment of deep vein thrombosis is designed to keep the aPTT between 1.5 and 2.5 times normal. With the client's aPTT level elevated to 80 seconds from a baseline of 30 seconds, it indicates that the current rate of heparin infusion is too high. Lowering the rate of infusion is necessary to bring the aPTT within the desired therapeutic range. Choices A, B, and D are incorrect because shutting off the infusion, increasing the rate, or leaving it as is would not address the elevated aPTT level and may lead to complications.

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