HESI RN
Biology Practice Test
1. Which of the following do prokaryotic cells lack?
- A. A cell membrane
- B. Genetic material
- C. Cytoplasm
- D. Membrane-bound organelles
Correct answer: D
Rationale: The correct answer is D: Prokaryotic cells lack membrane-bound organelles, such as mitochondria or a nucleus, distinguishing them from eukaryotic cells. Prokaryotic cells do have genetic material, a cell membrane, and cytoplasm. Choice A is incorrect because prokaryotic cells do have a cell membrane, which is essential for maintaining cell structure and regulating what enters and exits the cell. Choice B is incorrect because prokaryotic cells contain genetic material, typically in the form of a single circular chromosome. Choice C is incorrect because prokaryotic cells have cytoplasm, where various cellular activities take place.
2. The liver is an organ responsible for detoxifying the body of many harmful substances. You might expect the liver to contain a high amount of which of the following?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Mitochondria
- D. Lysosomes
Correct answer: B
Rationale: The correct answer is B: Smooth endoplasmic reticulum. The liver contains a high amount of smooth endoplasmic reticulum because it plays a significant role in detoxification processes, such as the synthesis of detoxifying enzymes and lipids. Choice A (Rough endoplasmic reticulum) is incorrect because the rough endoplasmic reticulum is more involved in protein synthesis and processing. Choice C (Mitochondria) is incorrect as mitochondria are primarily responsible for energy production. Choice D (Lysosomes) is incorrect because lysosomes are organelles involved in intracellular digestion and waste removal, not specifically related to detoxification.
3. Binary fission is a type of asexual reproduction. Which of the following occurs during the binary fission process?
- A. The chromosomes bind to the plasma membrane
- B. The chromosomes attach to the spindle formed along the axis
- C. The chromosomes gather in the center of the cell
- D. The chromosomes begin to separate
Correct answer: A
Rationale: The correct answer is A. In binary fission, the chromosomes bind to the plasma membrane before the cell splits into two. This initial step ensures that each daughter cell receives a complete set of genetic material. Choice B is incorrect because the spindle apparatus is characteristic of eukaryotic cell division (mitosis), not prokaryotic binary fission. Choice C is incorrect as chromosomes do not necessarily gather in the center of the cell during binary fission. Choice D is incorrect because the chromosomes do not begin to separate in binary fission; they replicate and then move to opposite ends of the cell before division.
4. DNA and RNA are both subunits of which biological molecule?
- A. Nucleic acids
- B. Proteins
- C. Carbohydrates
- D. Lipids
Correct answer: A
Rationale: The correct answer is A: Nucleic acids. DNA and RNA are both types of nucleic acids, which are fundamental biological molecules responsible for storing and transmitting genetic information. Choice B, Proteins, are not subunits of DNA and RNA but are composed of amino acids. Carbohydrates, choice C, are another type of biological molecule involved in energy storage and structural support, not subunits of DNA and RNA. Lipids, choice D, are a diverse group of molecules that include fats, oils, and steroids, but they are not subunits of DNA and RNA.
5. What is the smallest and most basic unit of matter?
- A. Micromolecule
- B. Atom
- C. Organelle
- D. Molecule
Correct answer: B
Rationale: The correct answer is B, Atom. An atom is the smallest unit of matter that retains the properties of an element. Choice A, Micromolecule, is incorrect because molecules are composed of atoms bonded together, making them larger than individual atoms. Choice C, Organelle, is incorrect as organelles are structures within cells, not the basic unit of matter. Choice D, Molecule, is incorrect as molecules are made up of atoms bonded together, so they are not the smallest unit of matter.
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