HESI RN
Biology Practice Test
1. Which of the following do prokaryotic cells lack?
- A. A cell membrane
- B. Genetic material
- C. Cytoplasm
- D. Membrane-bound organelles
Correct answer: D
Rationale: The correct answer is D: Prokaryotic cells lack membrane-bound organelles, such as mitochondria or a nucleus, distinguishing them from eukaryotic cells. Prokaryotic cells do have genetic material, a cell membrane, and cytoplasm. Choice A is incorrect because prokaryotic cells do have a cell membrane, which is essential for maintaining cell structure and regulating what enters and exits the cell. Choice B is incorrect because prokaryotic cells contain genetic material, typically in the form of a single circular chromosome. Choice C is incorrect because prokaryotic cells have cytoplasm, where various cellular activities take place.
2. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?
- A. They are gathered on either side of the separating cell
- B. They are all aligned along the metaphase plate
- C. They are attached to the spindle
- D. They are visibly separate
Correct answer: D
Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.
3. Which of the following best describes phenotype?
- A. The hereditary potentials and limitations of an individual
- B. The genetic makeup of an individual organism
- C. The entire complex of genes inherited from both parents
- D. All the observable characteristics of an organism
Correct answer: D
Rationale: The correct answer is D: 'All the observable characteristics of an organism.' Phenotype refers to all the observable characteristics of an organism, such as physical appearance, behavior, and other traits, which result from the interaction of its genotype with the environment. Choice A is incorrect because it describes genotype. Choice B is incorrect as it defines genotype, not phenotype. Choice C is incorrect as it refers to the genotype, the genetic information inherited from both parents, rather than the observable traits.
4. During which stage of mitosis do the chromosomes gather on either side of the separating cell?
- A. Metaphase
- B. Telophase
- C. Anaphase
- D. Prophase
Correct answer: B
Rationale: The correct answer is B, Telophase. During telophase, the chromosomes gather at opposite poles of the cell as the nuclear envelopes start to form around them, indicating the end of cell division. Choices A, C, and D are incorrect because during metaphase, the chromosomes align in the middle of the cell; in anaphase, the chromosomes separate and move towards opposite poles; and in prophase, the chromosomes condense and the nuclear envelope breaks down, respectively.
5. Where can ribosomes be found inside a cell?
- A. Attached to the endoplasmic reticulum (ER) and in the cytoplasm
- B. Within the cellular membrane
- C. Attached to the Golgi apparatus and in the cytoplasm
- D. Within the nucleus
Correct answer: A
Rationale: Ribosomes can be found attached to the endoplasmic reticulum (ER) or free-floating in the cytoplasm. The correct answer is A because ribosomes are responsible for synthesizing proteins and are commonly found on the ER or in the cytoplasm. Choice B is incorrect because ribosomes are not typically located within the cellular membrane. Choice C is incorrect as ribosomes are not attached to the Golgi apparatus; instead, they are involved in protein synthesis. Choice D is incorrect as ribosomes are not found within the nucleus but rather in the cytoplasm or attached to the ER.
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