HESI RN
Biology Practice Test
1. Which of the following do prokaryotic cells lack?
- A. A cell membrane
- B. Genetic material
- C. Cytoplasm
- D. Membrane-bound organelles
Correct answer: D
Rationale: The correct answer is D: Prokaryotic cells lack membrane-bound organelles, such as mitochondria or a nucleus, distinguishing them from eukaryotic cells. Prokaryotic cells do have genetic material, a cell membrane, and cytoplasm. Choice A is incorrect because prokaryotic cells do have a cell membrane, which is essential for maintaining cell structure and regulating what enters and exits the cell. Choice B is incorrect because prokaryotic cells contain genetic material, typically in the form of a single circular chromosome. Choice C is incorrect because prokaryotic cells have cytoplasm, where various cellular activities take place.
2. Which of the following statements is most accurate regarding the transcription of DNA?
- A. RNA uses reverse transcriptase to make mRNA
- B. DNA uses mRNA to produce tRNA
- C. RNA creates a duplicate copy of DNA
- D. RNA copies DNA to produce mRNA
Correct answer: D
Rationale: The correct answer is D. During transcription, RNA copies DNA to produce mRNA, which carries the genetic information from DNA to the ribosomes for protein synthesis. Choice A is incorrect because reverse transcriptase is not involved in the transcription of DNA. Choice B is incorrect as DNA does not use mRNA to produce tRNA; tRNA is produced through a different process. Choice C is incorrect as RNA does not create a duplicate copy of DNA during transcription; it synthesizes mRNA by copying the DNA template.
3. Who discovered the basic principles of genetics using garden peas?
- A. Curie
- B. Mendel
- C. Hawking
- D. Galileo
Correct answer: B
Rationale: The correct answer is B, Mendel. Gregor Mendel is known as the father of genetics for his groundbreaking work with pea plants. He discovered the basic principles of heredity through his experiments, establishing the foundation of modern genetics. Choice A, Curie, is incorrect as Marie Curie was a physicist and chemist known for her pioneering research on radioactivity. Choice C, Hawking, is incorrect as Stephen Hawking was a theoretical physicist known for his work on black holes and cosmology. Choice D, Galileo, is incorrect as Galileo Galilei was an astronomer and physicist renowned for his contributions to the scientific revolution, particularly in astronomy.
4. Which of the following options identifies the products of cell respiration?
- A. Water, carbon dioxide, and oxygen
- B. Glucose and oxygen
- C. Water, carbon dioxide, and adenosine triphosphate (ATP)
- D. Water, glucose, and oxygen
Correct answer: C
Rationale: The correct answer is C: 'Water, carbon dioxide, and adenosine triphosphate (ATP).' During cellular respiration, glucose is broken down in the presence of oxygen to produce water, carbon dioxide, and ATP. Choice A is incorrect as oxygen is not a product of cell respiration but a reactant. Choice B is incorrect as it lists glucose and oxygen, which are actually reactants in the process. Choice D is incorrect as glucose is not a product of cell respiration but a substrate that is broken down to release energy.
5. Which of the following is responsible for the synthesis of carbohydrates, lipids, and steroid hormones?
- A. Smooth endoplasmic reticulum (ER)
- B. Rough endoplasmic reticulum (ER)
- C. Golgi apparatus
- D. Ribosomes
Correct answer: A
Rationale: The smooth endoplasmic reticulum (ER) is the correct answer. It is responsible for the synthesis of lipids, including steroids, and also plays a role in carbohydrate metabolism. The rough endoplasmic reticulum (ER) is involved in protein synthesis and processing, not lipid or carbohydrate synthesis. The Golgi apparatus is responsible for modifying, sorting, and packaging of proteins and lipids, but not for their synthesis. Ribosomes are the cellular organelles responsible for protein synthesis, not lipid or carbohydrate synthesis.
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