HESI RN
Biology Practice Test
1. Which of the following do prokaryotic cells lack?
- A. A cell membrane
- B. Genetic material
- C. Cytoplasm
- D. Membrane-bound organelles
Correct answer: D
Rationale: The correct answer is D: Prokaryotic cells lack membrane-bound organelles, such as mitochondria or a nucleus, distinguishing them from eukaryotic cells. Prokaryotic cells do have genetic material, a cell membrane, and cytoplasm. Choice A is incorrect because prokaryotic cells do have a cell membrane, which is essential for maintaining cell structure and regulating what enters and exits the cell. Choice B is incorrect because prokaryotic cells contain genetic material, typically in the form of a single circular chromosome. Choice C is incorrect because prokaryotic cells have cytoplasm, where various cellular activities take place.
2. Which cell structure is responsible for efficiently packaging DNA into a small volume to fit into the nucleus of a cell and protect the DNA structure and sequence?
- A. Golgi apparatus
- B. Chromatin
- C. Smooth endoplasmic reticulum
- D. Mitochondria
Correct answer: B
Rationale: The correct answer is B: Chromatin. Chromatin is responsible for packaging DNA into a more compact, dense shape to fit into the nucleus of a cell. This compact packaging helps protect the DNA structure and regulate gene expression. The Golgi apparatus is involved in modifying, sorting, and packaging proteins. The smooth endoplasmic reticulum is involved in lipid metabolism and detoxification. Mitochondria are known as the powerhouse of the cell, producing energy in the form of ATP.
3. Who discovered the basic principles of genetics using garden peas?
- A. Curie
- B. Mendel
- C. Hawking
- D. Galileo
Correct answer: B
Rationale: The correct answer is B, Mendel. Gregor Mendel is known as the father of genetics for his groundbreaking work with pea plants. He discovered the basic principles of heredity through his experiments, establishing the foundation of modern genetics. Choice A, Curie, is incorrect as Marie Curie was a physicist and chemist known for her pioneering research on radioactivity. Choice C, Hawking, is incorrect as Stephen Hawking was a theoretical physicist known for his work on black holes and cosmology. Choice D, Galileo, is incorrect as Galileo Galilei was an astronomer and physicist renowned for his contributions to the scientific revolution, particularly in astronomy.
4. In which step of cellular respiration is the most adenosine triphosphate (ATP) created?
- A. Electron transport chain
- B. Glycolysis
- C. Citric acid cycle (the Krebs cycle)
- D. All of these produce equal amounts of ATP
Correct answer: A
Rationale: The electron transport chain is the step in cellular respiration that generates the most ATP. During this step, up to 34 ATP molecules can be produced from a single glucose molecule. Choice B, Glycolysis, produces a smaller amount of ATP (2 ATP molecules per glucose), and choice C, Citric acid cycle, produces some ATP but not as much as the electron transport chain. Choice D is incorrect because different steps of cellular respiration produce varying amounts of ATP, with the electron transport chain being the most efficient in ATP generation.
5. Binary fission is a type of asexual reproduction. Which of the following occurs during the binary fission process?
- A. The chromosomes bind to the plasma membrane
- B. The chromosomes attach to the spindle formed along the axis
- C. The chromosomes gather in the center of the cell
- D. The chromosomes begin to separate
Correct answer: A
Rationale: The correct answer is A. In binary fission, the chromosomes bind to the plasma membrane before the cell splits into two. This initial step ensures that each daughter cell receives a complete set of genetic material. Choice B is incorrect because the spindle apparatus is characteristic of eukaryotic cell division (mitosis), not prokaryotic binary fission. Choice C is incorrect as chromosomes do not necessarily gather in the center of the cell during binary fission. Choice D is incorrect because the chromosomes do not begin to separate in binary fission; they replicate and then move to opposite ends of the cell before division.
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