HESI RN
Biology Practice Test
1. Which of the following do prokaryotic cells lack?
- A. A cell membrane
- B. Genetic material
- C. Cytoplasm
- D. Membrane-bound organelles
Correct answer: D
Rationale: The correct answer is D: Prokaryotic cells lack membrane-bound organelles, such as mitochondria or a nucleus, distinguishing them from eukaryotic cells. Prokaryotic cells do have genetic material, a cell membrane, and cytoplasm. Choice A is incorrect because prokaryotic cells do have a cell membrane, which is essential for maintaining cell structure and regulating what enters and exits the cell. Choice B is incorrect because prokaryotic cells contain genetic material, typically in the form of a single circular chromosome. Choice C is incorrect because prokaryotic cells have cytoplasm, where various cellular activities take place.
2. Which of the following statements is most accurate regarding the transcription of DNA?
- A. RNA uses reverse transcriptase to make mRNA
- B. DNA uses mRNA to produce tRNA
- C. RNA creates a duplicate copy of DNA
- D. RNA copies DNA to produce mRNA
Correct answer: D
Rationale: The correct answer is D. During transcription, RNA copies DNA to produce mRNA, which carries the genetic information from DNA to the ribosomes for protein synthesis. Choice A is incorrect because reverse transcriptase is not involved in the transcription of DNA. Choice B is incorrect as DNA does not use mRNA to produce tRNA; tRNA is produced through a different process. Choice C is incorrect as RNA does not create a duplicate copy of DNA during transcription; it synthesizes mRNA by copying the DNA template.
3. What percentage of the parents' offspring is predicted to have a cleft chin if one parent carries the recessive gene for a cleft chin (c) while the other parent does not?
- A. 25%
- B. 50%
- C. 0%
- D. 75%
Correct answer: C
Rationale: The correct answer is C (0%). If one parent carries the recessive gene for a cleft chin while the other parent does not carry it, none of their offspring is predicted to have a cleft chin. This is because the cleft chin trait is recessive, so for an offspring to express this trait, they would need to inherit the gene from both parents. In this scenario, none of the offspring will inherit the recessive gene from both parents, so the percentage of offspring predicted to have a cleft chin is 0%. Choices A, B, and D are incorrect because in this situation, the offspring will not express the cleft chin phenotype, although they could be carriers of the recessive gene.
4. Phagocytes in the immune system are responsible for the biological action of which of the following?
- A. Secreting
- B. Consuming
- C. Altering
- D. Building
Correct answer: B
Rationale: The correct answer is B: Consuming. Phagocytes are cells that engulf and digest pathogens, dead cells, and other harmful particles, playing a crucial role in the immune system's defense. Phagocytes do not secrete substances, alter particles, or build structures; their primary function is to consume and eliminate harmful entities.
5. Which of the following processes produces nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FADH2) for the electron transport chain during cellular respiration?
- A. Electron transport chain
- B. Glycolysis
- C. Citric acid cycle (the Krebs cycle)
- D. None of these
Correct answer: C
Rationale: The correct answer is C, the citric acid cycle (the Krebs cycle). This cycle generates NADH and FADH2, which play a crucial role in providing electrons to the electron transport chain during cellular respiration. Choice A, the electron transport chain itself, is where NADH and FADH2 donate their electrons, not where they are produced. Choice B, glycolysis, produces NADH but not FADH2. Choice D, 'None of these,' is incorrect as the citric acid cycle specifically produces NADH and FADH2.
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