HESI RN
Biology Practice Test
1. What is located on the rough endoplasmic reticulum?
- A. Microvilli
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: D
Rationale: The rough endoplasmic reticulum is studded with ribosomes, which are responsible for protein synthesis. Ribosomes are the correct answer because they are the organelles directly associated with the rough endoplasmic reticulum. Microvilli (choice A), mitochondria (choice B), and lysosomes (choice C) are not typically located on the rough endoplasmic reticulum. Microvilli are found on the surface of cells to increase surface area, mitochondria are the powerhouses of the cell responsible for energy production, and lysosomes are membrane-bound organelles containing digestive enzymes.
2. In which step of cellular respiration is the most adenosine triphosphate (ATP) created?
- A. Electron transport chain
- B. Glycolysis
- C. Citric acid cycle (the Krebs cycle)
- D. All of these produce equal amounts of ATP
Correct answer: A
Rationale: The electron transport chain is the step in cellular respiration that generates the most ATP. During this step, up to 34 ATP molecules can be produced from a single glucose molecule. Choice B, Glycolysis, produces a smaller amount of ATP (2 ATP molecules per glucose), and choice C, Citric acid cycle, produces some ATP but not as much as the electron transport chain. Choice D is incorrect because different steps of cellular respiration produce varying amounts of ATP, with the electron transport chain being the most efficient in ATP generation.
3. Which organelle has the ability to hydrolyze fats, nucleic acids, proteins, and sugars?
- A. Chloroplasts
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: C
Rationale: The correct answer is C, Lysosomes. Lysosomes contain hydrolytic enzymes that are capable of breaking down various biomolecules such as fats, nucleic acids, proteins, and sugars. This organelle acts as the 'digestive system' of the cell. Choices A, B, and D are incorrect because chloroplasts are involved in photosynthesis, mitochondria are responsible for energy production, and ribosomes are responsible for protein synthesis, not the hydrolysis of biomolecules.
4. Proteins are polymers of 20 molecules called:
- A. Amino acids
- B. Phospholipids
- C. Carbohydrates
- D. Fatty acids
Correct answer: A
Rationale: Proteins are indeed polymers made up of amino acids. Amino acids are the building blocks of proteins, where each protein has a unique sequence of amino acids that determines its structure and function. Phospholipids, carbohydrates, and fatty acids are not molecules that make up proteins. Phospholipids are the main components of cell membranes, carbohydrates are sugars used for energy and structural purposes, and fatty acids are building blocks of lipids.
5. Protein synthesis begins with a process known as transcription. Where does this process occur?
- A. In the cytoplasm
- B. In the nuclear envelope
- C. In the ribosome unit
- D. In the nucleus
Correct answer: D
Rationale: The correct answer is D: In the nucleus. Transcription, the initial step of protein synthesis, takes place in the nucleus where DNA is transcribed into mRNA. This mRNA then leaves the nucleus and enters the cytoplasm where translation occurs on the ribosomes. Choices A, B, and C are incorrect because transcription specifically occurs in the nucleus, not in the cytoplasm, nuclear envelope, or ribosome unit.
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