HESI RN
Pharmacology HESI
1. A healthcare professional prepares to reinforce instructions to a client who is taking allopurinol (Zyloprim). The healthcare professional plans to include which of the following in the instructions?
- A. Instruct the client to drink 3000 mL of fluid per day.
- B. Instruct the client to take the medication with food.
- C. Inform the client that the effect of the medication will occur immediately.
- D. Instruct the client that, if swelling of the lips occurs, this is a normal expected response.
Correct answer: A
Rationale: Allopurinol is an antigout medication that works by reducing the production of uric acid in the body. To prevent kidney stones and promote the excretion of uric acid, increased fluid intake is essential. Instructing the client to drink 3000 mL of fluid per day helps to reduce the risk of kidney stones and assists in the elimination of uric acid, thereby enhancing the effectiveness of allopurinol therapy.
2. A client is instructed to take levothyroxine (Synthroid). The medication should be taken:
- A. With food
- B. At lunchtime
- C. On an empty stomach
- D. At bedtime with a snack
Correct answer: C
Rationale: Levothyroxine should be taken on an empty stomach to enhance absorption. Taking it with food or at bedtime can interfere with its absorption, reducing its effectiveness. Therefore, it is essential for the client to take levothyroxine on an empty stomach to ensure optimal therapeutic outcomes.
3. A client is being educated about the use of levodopa-carbidopa (Sinemet) for Parkinson's disease. Which statement by the client indicates a need for further teaching?
- A. I should avoid taking the medication with a high-protein meal.
- B. I may experience dizziness when getting up quickly.
- C. I might notice a darkening of my urine.
- D. I should report any uncontrolled movements to my healthcare provider.
Correct answer: A
Rationale: The correct answer is A. Levodopa-carbidopa (Sinemet) should not be taken with a high-protein meal as protein can interfere with the absorption of the medication. It is recommended to take it on an empty stomach or with a light meal. Choices B, C, and D are accurate statements regarding potential side effects and actions to take while on levodopa-carbidopa therapy, indicating a good understanding by the client.
4. A client who has begun taking fosinopril (Monopril) is very distressed, telling the nurse that he cannot taste food normally since beginning the medication 2 weeks ago. The nurse provides the best support to the client by:
- A. Telling the client not to take the medication with food
- B. Suggesting that the client taper the dose until taste returns to normal
- C. Informing the client that impaired taste is expected and generally disappears in 2 to 3 months
- D. Requesting that the health care provider (HCP) change the prescription to another brand of angiotensin-converting enzyme (ACE) inhibitor
Correct answer: C
Rationale: The correct answer is to inform the client that impaired taste is an expected side effect of ACE inhibitors like fosinopril, such as Monopril, and typically resolves within 2 to 3 months. It is essential for the nurse to offer reassurance and education to the client about this common side effect to alleviate distress and encourage compliance with the medication regimen.
5. The client has a PRN prescription for ondansetron (Zofran). For which condition should this medication be administered to the postoperative client?
- A. Paralytic ileus
- B. Incisional pain
- C. Urinary retention
- D. Nausea and vomiting
Correct answer: D
Rationale: Ondansetron, also known as Zofran, is an antiemetic medication primarily used to treat nausea and vomiting. In the postoperative setting, it is commonly administered to manage postoperative nausea and vomiting, which are frequent occurrences after surgery. Ondansetron works by blocking serotonin, a natural substance in the body that can trigger nausea and vomiting. It is also utilized to manage chemotherapy-induced nausea and vomiting. Therefore, the correct condition for which ondansetron should be administered to the postoperative client is nausea and vomiting.
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