HESI RN
Biology Test
1. Which of the following options correctly lists the five stages of mitosis in order from beginning to end?
- A. Prophase, Prometaphase, Telophase, Metaphase, Anaphase
- B. Prophase, Prometaphase, Metaphase, Anaphase, Telophase
- C. Metaphase, Anaphase, Prophase, Prometaphase, Telophase
- D. Metaphase, Telophase, Anaphase, Prophase, Prometaphase
Correct answer: B
Rationale: The correct order of the stages of mitosis is Prophase, Prometaphase, Metaphase, Anaphase, and Telophase. Choice A is incorrect because it has Anaphase and Metaphase in the wrong order. Choice C is incorrect as it starts with Metaphase, which is not the first stage of mitosis. Choice D is incorrect as it also has the stages in the wrong order, and it starts with Metaphase, which is incorrect.
2. Which of the following organelles is the site of cellular respiration?
- A. Nucleus
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: B
Rationale: The correct answer is B: Mitochondria. Mitochondria are known as the powerhouse of the cell because they generate most of the cell's supply of ATP through cellular respiration. The other organelles listed, such as the nucleus (choice A), lysosomes (choice C), and ribosomes (choice D), do not play a direct role in cellular respiration. The nucleus contains genetic material, lysosomes are involved in digestion and waste removal, and ribosomes are responsible for protein synthesis.
3. The liver is an organ responsible for detoxifying the body of many harmful substances. You might expect the liver to contain a high amount of which of the following?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Mitochondria
- D. Lysosomes
Correct answer: B
Rationale: The correct answer is B: Smooth endoplasmic reticulum. The liver contains a high amount of smooth endoplasmic reticulum because it plays a significant role in detoxification processes, such as the synthesis of detoxifying enzymes and lipids. Choice A (Rough endoplasmic reticulum) is incorrect because the rough endoplasmic reticulum is more involved in protein synthesis and processing. Choice C (Mitochondria) is incorrect as mitochondria are primarily responsible for energy production. Choice D (Lysosomes) is incorrect because lysosomes are organelles involved in intracellular digestion and waste removal, not specifically related to detoxification.
4. Protein synthesis begins with a process known as transcription. Where does this process occur?
- A. In the cytoplasm
- B. In the nuclear envelope
- C. In the ribosome unit
- D. In the nucleus
Correct answer: D
Rationale: The correct answer is D: In the nucleus. Transcription, the initial step of protein synthesis, takes place in the nucleus where DNA is transcribed into mRNA. This mRNA then leaves the nucleus and enters the cytoplasm where translation occurs on the ribosomes. Choices A, B, and C are incorrect because transcription specifically occurs in the nucleus, not in the cytoplasm, nuclear envelope, or ribosome unit.
5. Which of the following processes produces nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FADH2) for the electron transport chain during cellular respiration?
- A. Electron transport chain
- B. Glycolysis
- C. Citric acid cycle (the Krebs cycle)
- D. None of these
Correct answer: C
Rationale: The correct answer is C, the citric acid cycle (the Krebs cycle). This cycle generates NADH and FADH2, which play a crucial role in providing electrons to the electron transport chain during cellular respiration. Choice A, the electron transport chain itself, is where NADH and FADH2 donate their electrons, not where they are produced. Choice B, glycolysis, produces NADH but not FADH2. Choice D, 'None of these,' is incorrect as the citric acid cycle specifically produces NADH and FADH2.
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