HESI RN
Biology Test
1. During which stage of mitosis does the nuclear envelope begin to disappear and the chromosomes start attaching to the spindle forming along the cell's axis?
- A. Prometaphase
- B. Metaphase
- C. Anaphase
- D. Prophase
Correct answer: A
Rationale: The correct answer is A, Prometaphase. During prometaphase, the nuclear envelope disintegrates, and chromosomes start attaching to spindle fibers. In metaphase, chromosomes align in the middle of the cell. Anaphase is characterized by the separation of sister chromatids, and prophase involves the condensation of chromosomes and the beginning of spindle formation.
2. Which of the following makes it possible to predict the genotype and phenotype of the offspring of sexual reproduction?
- A. Punnett square
- B. Chi-square
- C. Microscope
- D. None of these
Correct answer: A
Rationale: The correct answer is A, Punnett square. A Punnett square is a tool specifically designed to predict the genotype and phenotype combinations of offspring resulting from a particular cross or breeding experiment. It helps in understanding the probability of different genotypes and phenotypes appearing in the offspring. Choice B, Chi-square, is a statistical test used to determine if there is a significant difference between the expected frequencies and the observed frequencies in a study. Choice C, Microscope, is used for viewing tiny structures and organisms, not for predicting genetic outcomes. Choice D, None of these, is incorrect as Punnett square is a valid tool for predicting genetic outcomes in offspring.
3. Which of the following molecules acts as the genetic code's messenger?
- A. RNA
- B. Proteins
- C. DNA
- D. Carbohydrates
Correct answer: A
Rationale: The correct answer is RNA. RNA, particularly mRNA, serves as the messenger that carries genetic information from DNA to the ribosome, where proteins are synthesized. Proteins (choice B) are not the genetic code's messenger; they are synthesized based on the information carried by RNA. DNA (choice C) stores the genetic information but does not directly act as the messenger. Carbohydrates (choice D) are not involved in transmitting genetic information.
4. What function does cholesterol, a phospholipid, serve within the cell membrane?
- A. It builds up fats to make the structure more flexible
- B. It allows protein channels to form
- C. It makes the structure very rigid and impermeable
- D. It stabilizes the membrane structure
Correct answer: D
Rationale: Cholesterol helps to maintain the fluidity and stability of the cell membrane by fitting between the phospholipid molecules. Choice A is incorrect because cholesterol does not build up fats in the cell membrane. Choice B is incorrect as protein channels are formed by proteins, not cholesterol. Choice C is incorrect as cholesterol actually helps regulate the fluidity of the membrane, making it less rigid and more permeable.
5. Which of the following statements is most accurate regarding the transcription of DNA?
- A. RNA uses reverse transcriptase to make mRNA
- B. DNA uses mRNA to produce tRNA
- C. RNA creates a duplicate copy of DNA
- D. RNA copies DNA to produce mRNA
Correct answer: D
Rationale: The correct answer is D. During transcription, RNA copies DNA to produce mRNA, which carries the genetic information from DNA to the ribosomes for protein synthesis. Choice A is incorrect because reverse transcriptase is not involved in the transcription of DNA. Choice B is incorrect as DNA does not use mRNA to produce tRNA; tRNA is produced through a different process. Choice C is incorrect as RNA does not create a duplicate copy of DNA during transcription; it synthesizes mRNA by copying the DNA template.
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