HESI RN
Biology Test
1. During which stage of mitosis does the nuclear envelope begin to disappear and the chromosomes start attaching to the spindle forming along the cell's axis?
- A. Prometaphase
- B. Metaphase
- C. Anaphase
- D. Prophase
Correct answer: A
Rationale: The correct answer is A, Prometaphase. During prometaphase, the nuclear envelope disintegrates, and chromosomes start attaching to spindle fibers. In metaphase, chromosomes align in the middle of the cell. Anaphase is characterized by the separation of sister chromatids, and prophase involves the condensation of chromosomes and the beginning of spindle formation.
2. Which of the following options is the term used to represent alternative versions of a gene?
- A. Alleles
- B. Binary fission
- C. Heterozygous
- D. Homozygous
Correct answer: A
Rationale: The correct answer is A: Alleles. Alleles are different forms of a gene that can exist at a specific locus on a chromosome. They represent variations in a gene's DNA sequence. Choices B, C, and D are incorrect. Binary fission is a form of asexual reproduction in single-celled organisms, while heterozygous and homozygous refer to different combinations of alleles in an individual, not the alternative versions of a gene.
3. What cell structure is responsible for efficiently packaging DNA into a small volume to fit into the nucleus of a cell and protect the DNA structure and sequence?
- A. Golgi apparatus
- B. Chromatin
- C. Smooth endoplasmic reticulum
- D. Mitochondria
Correct answer: B
Rationale: Chromatin is the correct answer. Chromatin is responsible for packaging DNA into a more compact, dense structure to fit into the nucleus and protect the DNA. The Golgi apparatus is involved in processing and packaging proteins, not DNA. Smooth endoplasmic reticulum is involved in lipid metabolism and detoxification. Mitochondria are known as the powerhouse of the cell responsible for energy production, not DNA packaging.
4. Protein synthesis begins with a process known as transcription. What is produced during this process?
- A. A codon
- B. A DNA helix
- C. A DNA strand
- D. An RNA strand
Correct answer: D
Rationale: The correct answer is D: An RNA strand. During transcription, the DNA template is used to produce an RNA strand, not a codon, DNA helix, or another DNA strand. A codon is a sequence of nucleotides that specifies a particular amino acid during translation, not produced during transcription. A DNA helix refers to the double-stranded structure of DNA, which is not produced during transcription. Another DNA strand is not produced during transcription since the process involves creating an RNA copy of a specific gene.
5. What must first occur before a cell can be divided to grow, develop, and reproduce organisms?
- A. RNA replication
- B. DNA replication
- C. Gene replication
- D. Chromosome replication
Correct answer: B
Rationale: The correct answer is B: DNA replication. Before a cell can divide to grow, develop, and reproduce organisms, DNA replication must occur. This process ensures that each daughter cell receives an identical set of genetic information. Choices A, C, and D are incorrect because while RNA, genes, and chromosomes are essential components of cell division, DNA replication is the specific process that must first occur to ensure accurate transmission of genetic material.
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