HESI RN
Biology Test
1. During which stage of mitosis does the nuclear envelope begin to disappear and the chromosomes start attaching to the spindle forming along the cell's axis?
- A. Prometaphase
- B. Metaphase
- C. Anaphase
- D. Prophase
Correct answer: A
Rationale: The correct answer is A, Prometaphase. During prometaphase, the nuclear envelope disintegrates, and chromosomes start attaching to spindle fibers. In metaphase, chromosomes align in the middle of the cell. Anaphase is characterized by the separation of sister chromatids, and prophase involves the condensation of chromosomes and the beginning of spindle formation.
2. Which of the following is often referred to as the powerhouse of the cell?
- A. Nucleus
- B. Chromatin
- C. Mitochondria
- D. Ribosomes
Correct answer: C
Rationale: Mitochondria are known as the powerhouse of the cell because they generate most of the cell's supply of ATP, which is the energy currency used for various cellular processes. The nucleus (Choice A) is the control center of the cell, housing genetic material. Chromatin (Choice B) is a complex of DNA and proteins within the nucleus. Ribosomes (Choice D) are responsible for protein synthesis and not the primary energy production in the cell.
3. In the hierarchical organizational system, which of these is the most restrictive category?
- A. Genus
- B. Class
- C. Kingdom
- D. Species
Correct answer: D
Rationale: In the biological classification hierarchy, species is the most specific level, defining individual organisms that can interbreed. While genus, class, and kingdom are also categories in the hierarchy, they are broader and encompass a wider range of organisms compared to species. Genus groups together similar species, class groups similar orders, and kingdom is the broadest category grouping together similar phyla.
4. Which of the following molecules contains the code required for replication?
- A. Deoxyribonucleic acid (DNA)
- B. Transfer RNA (tRNA)
- C. Messenger RNA (mRNA)
- D. Ribonucleic acid (RNA)
Correct answer: A
Rationale: The correct answer is A: Deoxyribonucleic acid (DNA). DNA contains the genetic information essential for replication, ensuring the accurate transmission of genetic material from one generation to the next. Choice B, Transfer RNA (tRNA), is involved in protein synthesis, not replication. Choice C, Messenger RNA (mRNA), carries genetic information from DNA to the ribosome but does not contain the code for replication. Choice D, Ribonucleic acid (RNA), is a broader category that includes both mRNA and tRNA, but the specific molecule containing the code required for replication is DNA.
5. During which stage of mitosis do the chromosomes gather on either side of the separating cell?
- A. Metaphase
- B. Telophase
- C. Anaphase
- D. Prophase
Correct answer: B
Rationale: The correct answer is B, Telophase. During telophase, the chromosomes gather at opposite poles of the cell as the nuclear envelopes start to form around them, indicating the end of cell division. Choices A, C, and D are incorrect because during metaphase, the chromosomes align in the middle of the cell; in anaphase, the chromosomes separate and move towards opposite poles; and in prophase, the chromosomes condense and the nuclear envelope breaks down, respectively.
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