HESI RN
Biology Test
1. Which organelle is responsible for the synthesis of lipids and steroid hormones?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Golgi apparatus
- D. Ribosomes
Correct answer: B
Rationale: The smooth endoplasmic reticulum is the correct organelle responsible for the synthesis of lipids, including phospholipids, cholesterol, and steroid hormones. The rough endoplasmic reticulum is primarily involved in protein synthesis and processing, making choice A incorrect. The Golgi apparatus is responsible for modifying, sorting, and packaging proteins and lipids for transportation, so it is not directly involved in lipid and steroid hormone synthesis, making choice C incorrect. Ribosomes are responsible for protein synthesis and are not involved in lipid or steroid hormone synthesis, making choice D incorrect.
2. DNA and RNA are both subunits of which biological molecule?
- A. Nucleic acids
- B. Proteins
- C. Carbohydrates
- D. Lipids
Correct answer: A
Rationale: The correct answer is A: Nucleic acids. DNA and RNA are both types of nucleic acids, which are fundamental biological molecules responsible for storing and transmitting genetic information. Choice B, Proteins, are not subunits of DNA and RNA but are composed of amino acids. Carbohydrates, choice C, are another type of biological molecule involved in energy storage and structural support, not subunits of DNA and RNA. Lipids, choice D, are a diverse group of molecules that include fats, oils, and steroids, but they are not subunits of DNA and RNA.
3. Which of the following is a lipid that is a membrane component and a precursor to significant hormones?
- A. Nucleic acids
- B. Proteins
- C. Carbohydrates
- D. Steroids
Correct answer: D
Rationale: The correct answer is D, Steroids. Steroids are a type of lipid that function as essential components of cell membranes and serve as precursors for significant hormones like estrogen and testosterone. Nucleic acids (choice A) are not lipids but are molecules like DNA and RNA that store genetic information. Proteins (choice B) and carbohydrates (choice C) are biomolecules but are not lipids and do not serve as precursors for hormones or membrane components.
4. What percentage of the offspring of the parents is predicted to have a cleft chin?
- A. 25%
- B. 50%
- C. 0%
- D. 75%
Correct answer: A
Rationale: When one parent carries the recessive gene for a cleft chin and the other does not, there is a 25% chance of the offspring inheriting the cleft chin. This is due to the fact that the trait follows a simple Mendelian inheritance pattern, where the offspring would need to inherit the recessive gene from both parents to express the trait. Therefore, 25% of the offspring are predicted to have a cleft chin. Choices B, C, and D are incorrect because the likelihood of inheriting a cleft chin in this specific scenario is 25%, not 50%, 0%, or 75%.
5. The term pleiotropy is best defined as which of the following?
- A. A situation in which one gene remains unexpressed
- B. One gene influencing multiple, seemingly unrelated phenotypic traits
- C. Two genes affected by a single allele
- D. A condition in which multiple genes are missing
Correct answer: B
Rationale: Pleiotropy is best defined as one gene influencing multiple, seemingly unrelated phenotypic traits. This phenomenon showcases the multifunctionality of genes, where a single gene can have effects on various aspects of an organism's phenotype. Choices A, C, and D do not accurately capture the concept of pleiotropy. Option A refers to gene expression, not pleiotropy. Option C describes genetic interactions but not in the context of pleiotropy. Option D talks about missing genes, which is unrelated to the definition of pleiotropy.
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