HESI RN
Biology Test
1. Which organelle is responsible for the synthesis of lipids and steroid hormones?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Golgi apparatus
- D. Ribosomes
Correct answer: B
Rationale: The smooth endoplasmic reticulum is the correct organelle responsible for the synthesis of lipids, including phospholipids, cholesterol, and steroid hormones. The rough endoplasmic reticulum is primarily involved in protein synthesis and processing, making choice A incorrect. The Golgi apparatus is responsible for modifying, sorting, and packaging proteins and lipids for transportation, so it is not directly involved in lipid and steroid hormone synthesis, making choice C incorrect. Ribosomes are responsible for protein synthesis and are not involved in lipid or steroid hormone synthesis, making choice D incorrect.
2. What is the main objective of the translation stage of protein synthesis?
- A. To produce amino acids
- B. To produce nucleotides
- C. To produce fatty acids
- D. To produce proteins
Correct answer: D
Rationale: The main objective of the translation stage of protein synthesis is to produce proteins. During translation, ribosomes decode mRNA sequences to synthesize proteins by linking amino acids together. Choice A, 'To produce amino acids,' is incorrect as amino acids are the building blocks of proteins and are not produced during translation. Choices B and C, 'To produce nucleotides' and 'To produce fatty acids,' are also incorrect as these molecules are not the direct products of the translation stage of protein synthesis.
3. Which of the following options correctly lists the five stages of mitosis in order from beginning to end?
- A. Prophase, Prometaphase, Telophase, Metaphase, Anaphase
- B. Prophase, Prometaphase, Metaphase, Anaphase, Telophase
- C. Metaphase, Anaphase, Prophase, Prometaphase, Telophase
- D. Metaphase, Telophase, Anaphase, Prophase, Prometaphase
Correct answer: B
Rationale: The correct order of the stages of mitosis is Prophase, Prometaphase, Metaphase, Anaphase, and Telophase. Choice A is incorrect because it has Anaphase and Metaphase in the wrong order. Choice C is incorrect as it starts with Metaphase, which is not the first stage of mitosis. Choice D is incorrect as it also has the stages in the wrong order, and it starts with Metaphase, which is incorrect.
4. What function does cholesterol, a phospholipid, serve within the cell membrane?
- A. It builds up fats to make the structure more flexible
- B. It allows protein channels to form
- C. It makes the structure very rigid and impermeable
- D. It stabilizes the membrane structure
Correct answer: D
Rationale: Cholesterol helps to maintain the fluidity and stability of the cell membrane by fitting between the phospholipid molecules. Choice A is incorrect because cholesterol does not build up fats in the cell membrane. Choice B is incorrect as protein channels are formed by proteins, not cholesterol. Choice C is incorrect as cholesterol actually helps regulate the fluidity of the membrane, making it less rigid and more permeable.
5. The term pleiotropy is best defined as which of the following?
- A. A situation in which one gene remains unexpressed
- B. One gene influencing multiple, seemingly unrelated phenotypic traits
- C. Two genes affected by a single allele
- D. A condition in which multiple genes are missing
Correct answer: B
Rationale: Pleiotropy is best defined as one gene influencing multiple, seemingly unrelated phenotypic traits. This phenomenon showcases the multifunctionality of genes, where a single gene can have effects on various aspects of an organism's phenotype. Choices A, C, and D do not accurately capture the concept of pleiotropy. Option A refers to gene expression, not pleiotropy. Option C describes genetic interactions but not in the context of pleiotropy. Option D talks about missing genes, which is unrelated to the definition of pleiotropy.
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