HESI RN
Biology Test
1. Which organelle is responsible for the synthesis of lipids and steroid hormones?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Golgi apparatus
- D. Ribosomes
Correct answer: B
Rationale: The smooth endoplasmic reticulum is the correct organelle responsible for the synthesis of lipids, including phospholipids, cholesterol, and steroid hormones. The rough endoplasmic reticulum is primarily involved in protein synthesis and processing, making choice A incorrect. The Golgi apparatus is responsible for modifying, sorting, and packaging proteins and lipids for transportation, so it is not directly involved in lipid and steroid hormone synthesis, making choice C incorrect. Ribosomes are responsible for protein synthesis and are not involved in lipid or steroid hormone synthesis, making choice D incorrect.
2. In the hierarchy of biology, cells combine to form which of the following?
- A. Macromolecules
- B. Molecules
- C. Tissues
- D. Organelles
Correct answer: C
Rationale: In the hierarchy of biology, cells combine to form tissues. Tissues are groups of cells that work together to perform specific functions. This is a fundamental level of organization above individual cells but below organs and organ systems. Macromolecules and molecules are smaller components that make up cells, not what cells combine to form. Organelles are structures within cells that perform specific functions and do not result from the combination of cells.
3. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?
- A. They are gathered on either side of the separating cell
- B. They are all aligned along the metaphase plate
- C. They are attached to the spindle
- D. They are visibly separate
Correct answer: D
Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.
4. What is the difference between DNA and RNA?
- A. RNA has an extra Phosphate group
- B. DNA has one less oxygen than RNA
- C. RNA has one less oxygen than DNA
- D. DNA has an extra sugar molecule
Correct answer: B
Rationale: The correct answer is B. DNA has one less oxygen atom in its sugar molecule (deoxyribose) compared to RNA, which has a ribose sugar. Choice A is incorrect because RNA does not have an extra phosphate group. Choice C is incorrect as RNA actually has one more oxygen atom than DNA. Choice D is incorrect as DNA and RNA have different sugar molecules, with DNA having deoxyribose and RNA having ribose.
5. In which step of cellular respiration is the most adenosine triphosphate (ATP) created?
- A. Electron transport chain
- B. Glycolysis
- C. Citric acid cycle (the Krebs cycle)
- D. All of these produce equal amounts of ATP
Correct answer: A
Rationale: The electron transport chain is the step in cellular respiration that generates the most ATP. During this step, up to 34 ATP molecules can be produced from a single glucose molecule. Choice B, Glycolysis, produces a smaller amount of ATP (2 ATP molecules per glucose), and choice C, Citric acid cycle, produces some ATP but not as much as the electron transport chain. Choice D is incorrect because different steps of cellular respiration produce varying amounts of ATP, with the electron transport chain being the most efficient in ATP generation.
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