HESI RN
Biology Test
1. Which cell structure is responsible for efficiently packaging DNA into a small volume to fit into the nucleus of a cell and protect the DNA structure and sequence?
- A. Golgi apparatus
- B. Chromatin
- C. Smooth endoplasmic reticulum
- D. Mitochondria
Correct answer: B
Rationale: The correct answer is B: Chromatin. Chromatin is responsible for packaging DNA into a more compact, dense shape to fit into the nucleus of a cell. This compact packaging helps protect the DNA structure and regulate gene expression. The Golgi apparatus is involved in modifying, sorting, and packaging proteins. The smooth endoplasmic reticulum is involved in lipid metabolism and detoxification. Mitochondria are known as the powerhouse of the cell, producing energy in the form of ATP.
2. The bilayer of the cellular membrane consists of phospholipids with all except which of the following scattered throughout?
- A. Nucleic acids
- B. Cholesterol
- C. Proteins
- D. Glycoproteins
Correct answer: A
Rationale: The cellular membrane is composed of a phospholipid bilayer with cholesterol, proteins, and glycoproteins distributed throughout. Nucleic acids are not found within the cellular membrane. Cholesterol helps maintain membrane fluidity, while proteins and glycoproteins play important roles in cell signaling, transport, and structural support.
3. During which stage of mitosis do the chromosomes gather on either side of the separating cell?
- A. Metaphase
- B. Telophase
- C. Anaphase
- D. Prophase
Correct answer: B
Rationale: The correct answer is B, Telophase. During telophase, the chromosomes gather at opposite poles of the cell as the nuclear envelopes start to form around them, indicating the end of cell division. Choices A, C, and D are incorrect because during metaphase, the chromosomes align in the middle of the cell; in anaphase, the chromosomes separate and move towards opposite poles; and in prophase, the chromosomes condense and the nuclear envelope breaks down, respectively.
4. What characteristic of water allows for hydrogen bonding between molecules?
- A. Its covalent bonds
- B. Its cohesive properties
- C. Its high specific heat
- D. Its polar nature
Correct answer: D
Rationale: The correct answer is D: Its polar nature. Water is a polar molecule with a partial positive charge on hydrogen atoms and a partial negative charge on oxygen atoms. This polarity allows water molecules to form hydrogen bonds with each other. Choice A, covalent bonds, is incorrect because while water indeed has covalent bonds, they do not directly enable hydrogen bonding. Choice B, cohesive properties, is incorrect as cohesion refers to water's ability to stick to other substances, not the specific characteristic that allows for hydrogen bonding. Choice C, high specific heat, is also incorrect as it refers to water's ability to resist changes in temperature, not its property that leads to hydrogen bonding.
5. In the hierarchy of biology, cells combine to form which of the following?
- A. Macromolecules
- B. Molecules
- C. Tissues
- D. Organelles
Correct answer: C
Rationale: In the hierarchy of biology, cells combine to form tissues. Tissues are groups of cells that work together to perform specific functions. This is a fundamental level of organization above individual cells but below organs and organ systems. Macromolecules and molecules are smaller components that make up cells, not what cells combine to form. Organelles are structures within cells that perform specific functions and do not result from the combination of cells.
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