HESI RN
Biology Practice Test
1. What is the main objective of the translation stage of protein synthesis?
- A. To produce amino acids
- B. To produce nucleotides
- C. To produce fatty acids
- D. To produce proteins
Correct answer: D
Rationale: The main objective of the translation stage of protein synthesis is to produce proteins. During translation, ribosomes decode mRNA sequences to synthesize proteins by linking amino acids together. Choice A, 'To produce amino acids,' is incorrect as amino acids are the building blocks of proteins and are not produced during translation. Choices B and C, 'To produce nucleotides' and 'To produce fatty acids,' are also incorrect as these molecules are not the direct products of the translation stage of protein synthesis.
2. Protein synthesis begins with a process known as transcription. Where does this process occur?
- A. In the cytoplasm
- B. In the nuclear envelope
- C. In the ribosome unit
- D. In the nucleus
Correct answer: D
Rationale: The correct answer is D: In the nucleus. Transcription, the initial step of protein synthesis, takes place in the nucleus where DNA is transcribed into mRNA. This mRNA then leaves the nucleus and enters the cytoplasm where translation occurs on the ribosomes. Choices A, B, and C are incorrect because transcription specifically occurs in the nucleus, not in the cytoplasm, nuclear envelope, or ribosome unit.
3. The liver is an organ responsible for detoxifying the body of many harmful substances. You might expect the liver to contain a high amount of which of the following?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Mitochondria
- D. Lysosomes
Correct answer: B
Rationale: The correct answer is B: Smooth endoplasmic reticulum. The liver contains a high amount of smooth endoplasmic reticulum because it plays a significant role in detoxification processes, such as the synthesis of detoxifying enzymes and lipids. Choice A (Rough endoplasmic reticulum) is incorrect because the rough endoplasmic reticulum is more involved in protein synthesis and processing. Choice C (Mitochondria) is incorrect as mitochondria are primarily responsible for energy production. Choice D (Lysosomes) is incorrect because lysosomes are organelles involved in intracellular digestion and waste removal, not specifically related to detoxification.
4. Water is held together by which of the following bonds?
- A. Electrostatic attraction
- B. Van der Waals forces
- C. Hydrogen
- D. Oxygen
Correct answer: C
Rationale: Water molecules are held together by hydrogen bonds, which are weak bonds formed between the slightly positive hydrogen atom of one water molecule and the slightly negative oxygen atom of another. Choice A, electrostatic attraction, is a general term for the attraction between opposite charges but does not specifically describe the bonds in water. Choice B, Van der Waals forces, are weak intermolecular forces that arise from temporary fluctuations in electron distribution, not the primary bonds in water. Choice D, oxygen, is incorrect as oxygen is part of the water molecule but not the bond holding water molecules together.
5. What is the difference between DNA and RNA?
- A. RNA has an extra Phosphate group
- B. DNA has one less oxygen than RNA
- C. RNA has one less oxygen than DNA
- D. DNA has an extra sugar molecule
Correct answer: B
Rationale: The correct answer is B. DNA has one less oxygen atom in its sugar molecule (deoxyribose) compared to RNA, which has a ribose sugar. Choice A is incorrect because RNA does not have an extra phosphate group. Choice C is incorrect as RNA actually has one more oxygen atom than DNA. Choice D is incorrect as DNA and RNA have different sugar molecules, with DNA having deoxyribose and RNA having ribose.
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