HESI RN
Biology Practice Test
1. The liver is an organ responsible for detoxifying the body of many harmful substances. You might expect the liver to contain a high amount of which of the following?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Mitochondria
- D. Lysosomes
Correct answer: B
Rationale: The correct answer is B: Smooth endoplasmic reticulum. The liver contains a high amount of smooth endoplasmic reticulum because it plays a significant role in detoxification processes, such as the synthesis of detoxifying enzymes and lipids. Choice A (Rough endoplasmic reticulum) is incorrect because the rough endoplasmic reticulum is more involved in protein synthesis and processing. Choice C (Mitochondria) is incorrect as mitochondria are primarily responsible for energy production. Choice D (Lysosomes) is incorrect because lysosomes are organelles involved in intracellular digestion and waste removal, not specifically related to detoxification.
2. Which of the following molecules contains the code required for replication?
- A. Deoxyribonucleic acid (DNA)
- B. Transfer RNA (tRNA)
- C. Messenger RNA (mRNA)
- D. Ribonucleic acid (RNA)
Correct answer: A
Rationale: The correct answer is A: Deoxyribonucleic acid (DNA). DNA contains the genetic information essential for replication, ensuring the accurate transmission of genetic material from one generation to the next. Choice B, Transfer RNA (tRNA), is involved in protein synthesis, not replication. Choice C, Messenger RNA (mRNA), carries genetic information from DNA to the ribosome but does not contain the code for replication. Choice D, Ribonucleic acid (RNA), is a broader category that includes both mRNA and tRNA, but the specific molecule containing the code required for replication is DNA.
3. A molecule's specific heat is the amount of heat necessary to raise the temperature of 1 gram of that molecule by:
- A. One degree Celsius
- B. Five degrees Celsius
- C. Two degrees Celsius
- D. Four degrees Celsius
Correct answer: A
Rationale: The correct answer is A: 'One degree Celsius.' Specific heat is defined as the amount of heat required to raise the temperature of one gram of a substance by one degree Celsius. This property is specific to each substance and is used in various calculations involving heat and temperature changes. Choices B, C, and D are incorrect because specific heat is always measured per one degree Celsius increase in temperature for one gram of the substance, not five degrees, two degrees, or four degrees.
4. Which of the following do prokaryotic cells lack?
- A. A cell membrane
- B. Genetic material
- C. Cytoplasm
- D. Membrane-bound organelles
Correct answer: D
Rationale: The correct answer is D: Prokaryotic cells lack membrane-bound organelles, such as mitochondria or a nucleus, distinguishing them from eukaryotic cells. Prokaryotic cells do have genetic material, a cell membrane, and cytoplasm. Choice A is incorrect because prokaryotic cells do have a cell membrane, which is essential for maintaining cell structure and regulating what enters and exits the cell. Choice B is incorrect because prokaryotic cells contain genetic material, typically in the form of a single circular chromosome. Choice C is incorrect because prokaryotic cells have cytoplasm, where various cellular activities take place.
5. What are the nitrogenous bases of DNA?
- A. Adenine, cytosine, guanine, and thymine
- B. Adenine, guanine, and uracil
- C. Adenine, guanine, and thymine
- D. Adenine, cytosine, guanine, and uracil
Correct answer: A
Rationale: The correct answer is A: Adenine, cytosine, guanine, and thymine. These are the four nitrogenous bases found in DNA. Adenine pairs with thymine, and cytosine pairs with guanine, forming the complementary base pairs in the double helix structure of DNA. Choice B is incorrect because uracil is a nitrogenous base found in RNA, not DNA. Choice C is incorrect as it is missing cytosine, one of the four bases in DNA. Choice D is incorrect because uracil is not a nitrogenous base in DNA, and it also lacks thymine, which is essential for DNA structure.
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