HESI RN
Biology Practice Test
1. Protein synthesis begins with a process known as transcription. Where does this process occur?
- A. In the cytoplasm
- B. In the nuclear envelope
- C. In the ribosome unit
- D. In the nucleus
Correct answer: D
Rationale: The correct answer is D: In the nucleus. Transcription, the initial step of protein synthesis, takes place in the nucleus where DNA is transcribed into mRNA. This mRNA then leaves the nucleus and enters the cytoplasm where translation occurs on the ribosomes. Choices A, B, and C are incorrect because transcription specifically occurs in the nucleus, not in the cytoplasm, nuclear envelope, or ribosome unit.
2. During which stage of mitosis do the chromosomes gather on either side of the separating cell?
- A. Metaphase
- B. Telophase
- C. Anaphase
- D. Prophase
Correct answer: B
Rationale: The correct answer is B, Telophase. During telophase, the chromosomes gather at opposite poles of the cell as the nuclear envelopes start to form around them, indicating the end of cell division. Choices A, C, and D are incorrect because during metaphase, the chromosomes align in the middle of the cell; in anaphase, the chromosomes separate and move towards opposite poles; and in prophase, the chromosomes condense and the nuclear envelope breaks down, respectively.
3. Binary fission is a type of asexual reproduction. Which of the following occurs during the binary fission process?
- A. The chromosomes bind to the plasma membrane
- B. The chromosomes attach to the spindle formed along the axis
- C. The chromosomes gather in the center of the cell
- D. The chromosomes begin to separate
Correct answer: A
Rationale: The correct answer is A. In binary fission, the chromosomes bind to the plasma membrane before the cell splits into two. This initial step ensures that each daughter cell receives a complete set of genetic material. Choice B is incorrect because the spindle apparatus is characteristic of eukaryotic cell division (mitosis), not prokaryotic binary fission. Choice C is incorrect as chromosomes do not necessarily gather in the center of the cell during binary fission. Choice D is incorrect because the chromosomes do not begin to separate in binary fission; they replicate and then move to opposite ends of the cell before division.
4. What is the difference between DNA and RNA?
- A. RNA has an extra Phosphate group
- B. DNA has one less oxygen than RNA
- C. RNA has one less oxygen than DNA
- D. DNA has an extra sugar molecule
Correct answer: B
Rationale: The correct answer is B. DNA has one less oxygen atom in its sugar molecule (deoxyribose) compared to RNA, which has a ribose sugar. Choice A is incorrect because RNA does not have an extra phosphate group. Choice C is incorrect as RNA actually has one more oxygen atom than DNA. Choice D is incorrect as DNA and RNA have different sugar molecules, with DNA having deoxyribose and RNA having ribose.
5. What cell structure is responsible for efficiently packaging DNA into a small volume to fit into the nucleus of a cell and protect the DNA structure and sequence?
- A. Golgi apparatus
- B. Chromatin
- C. Smooth endoplasmic reticulum
- D. Mitochondria
Correct answer: B
Rationale: Chromatin is the correct answer. Chromatin is responsible for packaging DNA into a more compact, dense structure to fit into the nucleus and protect the DNA. The Golgi apparatus is involved in processing and packaging proteins, not DNA. Smooth endoplasmic reticulum is involved in lipid metabolism and detoxification. Mitochondria are known as the powerhouse of the cell responsible for energy production, not DNA packaging.
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