HESI RN
Biology Practice Test
1. Protein synthesis begins with a process known as transcription. Where does this process occur?
- A. In the cytoplasm
- B. In the nuclear envelope
- C. In the ribosome unit
- D. In the nucleus
Correct answer: D
Rationale: The correct answer is D: In the nucleus. Transcription, the initial step of protein synthesis, takes place in the nucleus where DNA is transcribed into mRNA. This mRNA then leaves the nucleus and enters the cytoplasm where translation occurs on the ribosomes. Choices A, B, and C are incorrect because transcription specifically occurs in the nucleus, not in the cytoplasm, nuclear envelope, or ribosome unit.
2. Proteins are polymers of 20 molecules called:
- A. Amino acids
- B. Phospholipids
- C. Carbohydrates
- D. Fatty acids
Correct answer: A
Rationale: Proteins are indeed polymers made up of amino acids. Amino acids are the building blocks of proteins, where each protein has a unique sequence of amino acids that determines its structure and function. Phospholipids, carbohydrates, and fatty acids are not molecules that make up proteins. Phospholipids are the main components of cell membranes, carbohydrates are sugars used for energy and structural purposes, and fatty acids are building blocks of lipids.
3. Which of the following statements is most accurate regarding the transcription of DNA?
- A. RNA uses reverse transcriptase to make mRNA
- B. DNA uses mRNA to produce tRNA
- C. RNA creates a duplicate copy of DNA
- D. RNA copies DNA to produce mRNA
Correct answer: D
Rationale: The correct answer is D. During transcription, RNA copies DNA to produce mRNA, which carries the genetic information from DNA to the ribosomes for protein synthesis. Choice A is incorrect because reverse transcriptase is not involved in the transcription of DNA. Choice B is incorrect as DNA does not use mRNA to produce tRNA; tRNA is produced through a different process. Choice C is incorrect as RNA does not create a duplicate copy of DNA during transcription; it synthesizes mRNA by copying the DNA template.
4. Which of the following molecules contains the code required for replication?
- A. Deoxyribonucleic acid (DNA)
- B. Transfer RNA (tRNA)
- C. Messenger RNA (mRNA)
- D. Ribonucleic acid (RNA)
Correct answer: A
Rationale: The correct answer is A: Deoxyribonucleic acid (DNA). DNA contains the genetic information essential for replication, ensuring the accurate transmission of genetic material from one generation to the next. Choice B, Transfer RNA (tRNA), is involved in protein synthesis, not replication. Choice C, Messenger RNA (mRNA), carries genetic information from DNA to the ribosome but does not contain the code for replication. Choice D, Ribonucleic acid (RNA), is a broader category that includes both mRNA and tRNA, but the specific molecule containing the code required for replication is DNA.
5. Which of the following best describes phenotype?
- A. The hereditary potentials and limitations of an individual
- B. The genetic makeup of an individual organism
- C. The entire complex of genes inherited from both parents
- D. All the observable characteristics of an organism
Correct answer: D
Rationale: The correct answer is D: 'All the observable characteristics of an organism.' Phenotype refers to all the observable characteristics of an organism, such as physical appearance, behavior, and other traits, which result from the interaction of its genotype with the environment. Choice A is incorrect because it describes genotype. Choice B is incorrect as it defines genotype, not phenotype. Choice C is incorrect as it refers to the genotype, the genetic information inherited from both parents, rather than the observable traits.
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