HESI RN
Biology Practice Test
1. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?
- A. They are gathered on either side of the separating cell
- B. They are all aligned along the metaphase plate
- C. They are attached to the spindle
- D. They are visibly separate
Correct answer: D
Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.
2. Which of the following is not one of the four nitrogenous bases that make up the DNA structure?
- A. Adenine
- B. Guanine
- C. Uracil
- D. Thymine
Correct answer: C
Rationale: The correct answer is C: Uracil. Uracil is found in RNA, not DNA. The four nitrogenous bases in DNA are adenine, thymine, cytosine, and guanine. Choice A, Adenine, is a nitrogenous base in DNA. Choice B, Guanine, is another nitrogenous base in DNA. Choice D, Thymine, is also one of the four nitrogenous bases in DNA. Therefore, the correct answer is Uracil (Choice C).
3. Water is held together by which of the following bonds?
- A. Electrostatic attraction
- B. Van der Waals forces
- C. Hydrogen
- D. Oxygen
Correct answer: C
Rationale: Water molecules are held together by hydrogen bonds, which are weak bonds formed between the slightly positive hydrogen atom of one water molecule and the slightly negative oxygen atom of another. Choice A, electrostatic attraction, is a general term for the attraction between opposite charges but does not specifically describe the bonds in water. Choice B, Van der Waals forces, are weak intermolecular forces that arise from temporary fluctuations in electron distribution, not the primary bonds in water. Choice D, oxygen, is incorrect as oxygen is part of the water molecule but not the bond holding water molecules together.
4. At the beginning of meiosis, how many chromosomes does the diploid parent cell have?
- A. 23
- B. 24
- C. 46
- D. 54
Correct answer: C
Rationale: The correct answer is C: 46. At the start of meiosis, the diploid parent cell contains 46 chromosomes. During meiosis, the number of chromosomes is halved, resulting in each gamete having 23 chromosomes. Choice A (23) is incorrect because that is the number of chromosomes in a human gamete, not the parent cell. Choice B (24) and Choice D (54) are also incorrect as they do not reflect the correct number of chromosomes in a diploid parent cell at the beginning of meiosis.
5. The liver is an organ responsible for detoxifying the body of many harmful substances. You might expect the liver to contain a high amount of which of the following?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Mitochondria
- D. Lysosomes
Correct answer: B
Rationale: The correct answer is B: Smooth endoplasmic reticulum. The liver contains a high amount of smooth endoplasmic reticulum because it plays a significant role in detoxification processes, such as the synthesis of detoxifying enzymes and lipids. Choice A (Rough endoplasmic reticulum) is incorrect because the rough endoplasmic reticulum is more involved in protein synthesis and processing. Choice C (Mitochondria) is incorrect as mitochondria are primarily responsible for energy production. Choice D (Lysosomes) is incorrect because lysosomes are organelles involved in intracellular digestion and waste removal, not specifically related to detoxification.
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