HESI RN
Biology Practice Test
1. In which step of cellular respiration is the most adenosine triphosphate (ATP) created?
- A. Electron transport chain
- B. Glycolysis
- C. Citric acid cycle (the Krebs cycle)
- D. All of these produce equal amounts of ATP
Correct answer: A
Rationale: The electron transport chain is the step in cellular respiration that generates the most ATP. During this step, up to 34 ATP molecules can be produced from a single glucose molecule. Choice B, Glycolysis, produces a smaller amount of ATP (2 ATP molecules per glucose), and choice C, Citric acid cycle, produces some ATP but not as much as the electron transport chain. Choice D is incorrect because different steps of cellular respiration produce varying amounts of ATP, with the electron transport chain being the most efficient in ATP generation.
2. What is the difference between DNA and RNA?
- A. RNA has an extra Phosphate group
- B. DNA has one less oxygen than RNA
- C. RNA has one less oxygen than DNA
- D. DNA has an extra sugar molecule
Correct answer: B
Rationale: The correct answer is B. DNA has one less oxygen atom in its sugar molecule (deoxyribose) compared to RNA, which has a ribose sugar. Choice A is incorrect because RNA does not have an extra phosphate group. Choice C is incorrect as RNA actually has one more oxygen atom than DNA. Choice D is incorrect as DNA and RNA have different sugar molecules, with DNA having deoxyribose and RNA having ribose.
3. Which of the following makes it possible to predict the genotype and phenotype of the offspring of sexual reproduction?
- A. Punnett square
- B. Chi-square
- C. Microscope
- D. None of these
Correct answer: A
Rationale: The correct answer is A, Punnett square. A Punnett square is a tool specifically designed to predict the genotype and phenotype combinations of offspring resulting from a particular cross or breeding experiment. It helps in understanding the probability of different genotypes and phenotypes appearing in the offspring. Choice B, Chi-square, is a statistical test used to determine if there is a significant difference between the expected frequencies and the observed frequencies in a study. Choice C, Microscope, is used for viewing tiny structures and organisms, not for predicting genetic outcomes. Choice D, None of these, is incorrect as Punnett square is a valid tool for predicting genetic outcomes in offspring.
4. The bilayer of the cellular membrane consists of phospholipids with all except which of the following scattered throughout?
- A. Nucleic acids
- B. Cholesterol
- C. Proteins
- D. Glycoproteins
Correct answer: A
Rationale: The cellular membrane is composed of a phospholipid bilayer with cholesterol, proteins, and glycoproteins distributed throughout. Nucleic acids are not found within the cellular membrane. Cholesterol helps maintain membrane fluidity, while proteins and glycoproteins play important roles in cell signaling, transport, and structural support.
5. During which stage of mitosis do the chromosomes gather on either side of the separating cell?
- A. Metaphase
- B. Telophase
- C. Anaphase
- D. Prophase
Correct answer: B
Rationale: The correct answer is B, Telophase. During telophase, the chromosomes gather at opposite poles of the cell as the nuclear envelopes start to form around them, indicating the end of cell division. Choices A, C, and D are incorrect because during metaphase, the chromosomes align in the middle of the cell; in anaphase, the chromosomes separate and move towards opposite poles; and in prophase, the chromosomes condense and the nuclear envelope breaks down, respectively.
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