HESI RN
Biology Practice Test
1. Which of the following is not one of the four nitrogenous bases that make up the DNA structure?
- A. Adenine
- B. Guanine
- C. Uracil
- D. Thymine
Correct answer: C
Rationale: The correct answer is C: Uracil. Uracil is found in RNA, not DNA. The four nitrogenous bases in DNA are adenine, thymine, cytosine, and guanine. Choice A, Adenine, is a nitrogenous base in DNA. Choice B, Guanine, is another nitrogenous base in DNA. Choice D, Thymine, is also one of the four nitrogenous bases in DNA. Therefore, the correct answer is Uracil (Choice C).
2. What is the most significant contributor to cellular function?
- A. Proteins
- B. Phospholipids
- C. Carbohydrates
- D. Fatty acids
Correct answer: A
Rationale: The correct answer is A: Proteins. Proteins are the most significant contributor to cellular function as they play crucial roles in almost all biological processes. They act as enzymes that catalyze reactions, are involved in cell signaling pathways, and provide structural support to cells. Phospholipids (Choice B), while important for cell membrane structure, do not have the same diverse functions as proteins in cellular processes. Carbohydrates (Choice C) primarily serve as an energy source and structural components but are not as versatile in cellular functions as proteins. Fatty acids (Choice D) are essential components of cell membranes and energy storage molecules but do not have the same broad range of functions as proteins in cellular processes.
3. Which of the following serves as the information processing and administrative center of the cell?
- A. Golgi apparatus
- B. Cytoplasm
- C. Nucleus
- D. Lysosomes
Correct answer: C
Rationale: The correct answer is C, the nucleus. The nucleus is indeed the information processing and administrative center of the cell as it contains the genetic material (DNA) and is responsible for controlling cellular activities. The Golgi apparatus (Choice A) is involved in processing and packaging proteins, the cytoplasm (Choice B) is the fluid that fills the cell and provides a medium for organelles to be suspended, and lysosomes (Choice D) are responsible for digesting waste materials and foreign invaders. Therefore, the nucleus is the most appropriate choice for the given function.
4. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?
- A. They are gathered on either side of the separating cell
- B. They are all aligned along the metaphase plate
- C. They are attached to the spindle
- D. They are visibly separate
Correct answer: D
Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.
5. Which of the following is responsible for the synthesis of carbohydrates, lipids, and steroid hormones?
- A. Smooth endoplasmic reticulum (ER)
- B. Rough endoplasmic reticulum (ER)
- C. Golgi apparatus
- D. Ribosomes
Correct answer: A
Rationale: The smooth endoplasmic reticulum (ER) is the correct answer. It is responsible for the synthesis of lipids, including steroids, and also plays a role in carbohydrate metabolism. The rough endoplasmic reticulum (ER) is involved in protein synthesis and processing, not lipid or carbohydrate synthesis. The Golgi apparatus is responsible for modifying, sorting, and packaging of proteins and lipids, but not for their synthesis. Ribosomes are the cellular organelles responsible for protein synthesis, not lipid or carbohydrate synthesis.
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