HESI RN
Biology Practice Test
1. Which of the following is not one of the four nitrogenous bases that make up the DNA structure?
- A. Adenine
- B. Guanine
- C. Uracil
- D. Thymine
Correct answer: C
Rationale: The correct answer is C: Uracil. Uracil is found in RNA, not DNA. The four nitrogenous bases in DNA are adenine, thymine, cytosine, and guanine. Choice A, Adenine, is a nitrogenous base in DNA. Choice B, Guanine, is another nitrogenous base in DNA. Choice D, Thymine, is also one of the four nitrogenous bases in DNA. Therefore, the correct answer is Uracil (Choice C).
2. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?
- A. They are gathered on either side of the separating cell
- B. They are all aligned along the metaphase plate
- C. They are attached to the spindle
- D. They are visibly separate
Correct answer: D
Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.
3. What characteristic of water allows for hydrogen bonding between molecules?
- A. Its covalent bonds
- B. Its cohesive properties
- C. Its high specific heat
- D. Its polar nature
Correct answer: D
Rationale: The correct answer is D: Its polar nature. Water is a polar molecule with a partial positive charge on hydrogen atoms and a partial negative charge on oxygen atoms. This polarity allows water molecules to form hydrogen bonds with each other. Choice A, covalent bonds, is incorrect because while water indeed has covalent bonds, they do not directly enable hydrogen bonding. Choice B, cohesive properties, is incorrect as cohesion refers to water's ability to stick to other substances, not the specific characteristic that allows for hydrogen bonding. Choice C, high specific heat, is also incorrect as it refers to water's ability to resist changes in temperature, not its property that leads to hydrogen bonding.
4. In which of the following does cellular respiration take place?
- A. Golgi apparatus
- B. Mitochondrion
- C. Chloroplast
- D. Ribosome
Correct answer: B
Rationale: The correct answer is B, Mitochondrion. Cellular respiration occurs in the mitochondria, where glucose is converted into energy through a series of metabolic processes. Choice A, Golgi apparatus, is incorrect as it is involved in modifying, sorting, and packaging proteins. Choice C, Chloroplast, is incorrect as it is the site of photosynthesis in plant cells, not cellular respiration. Choice D, Ribosome, is incorrect as it is responsible for protein synthesis, not energy production through cellular respiration.
5. Which organelle has the ability to hydrolyze fats, nucleic acids, proteins, and sugars?
- A. Chloroplasts
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: C
Rationale: The correct answer is C, Lysosomes. Lysosomes contain hydrolytic enzymes that are capable of breaking down various biomolecules such as fats, nucleic acids, proteins, and sugars. This organelle acts as the 'digestive system' of the cell. Choices A, B, and D are incorrect because chloroplasts are involved in photosynthesis, mitochondria are responsible for energy production, and ribosomes are responsible for protein synthesis, not the hydrolysis of biomolecules.
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