HESI RN
Biology Practice Test
1. In the hierarchy of biology, cells combine to form which of the following?
- A. Macromolecules
- B. Molecules
- C. Tissues
- D. Organelles
Correct answer: C
Rationale: In the hierarchy of biology, cells combine to form tissues. Tissues are groups of cells that work together to perform specific functions. This is a fundamental level of organization above individual cells but below organs and organ systems. Macromolecules and molecules are smaller components that make up cells, not what cells combine to form. Organelles are structures within cells that perform specific functions and do not result from the combination of cells.
2. Which of the following is not true of mitosis?
- A. Mitosis produces daughter cells
- B. Mitosis has five main stages
- C. Mitosis can only be done by haploids
- D. Following mitosis, daughter cells are identical to parent cells
Correct answer: C
Rationale: The correct answer is C. Mitosis occurs in diploid cells and involves stages that result in the production of two identical daughter cells. Haploids do not undergo mitosis, as mitosis is a process specific to diploid cells. Choice A is true as mitosis does produce daughter cells. Choice B is incorrect as mitosis typically consists of four main stages: prophase, metaphase, anaphase, and telophase. Choice D is true, as one of the main outcomes of mitosis is the production of daughter cells that are genetically identical to the parent cell.
3. The liver is an organ responsible for detoxifying the body of many harmful substances. You might expect the liver to contain a high amount of which of the following?
- A. Rough endoplasmic reticulum
- B. Smooth endoplasmic reticulum
- C. Mitochondria
- D. Lysosomes
Correct answer: B
Rationale: The correct answer is B: Smooth endoplasmic reticulum. The liver contains a high amount of smooth endoplasmic reticulum because it plays a significant role in detoxification processes, such as the synthesis of detoxifying enzymes and lipids. Choice A (Rough endoplasmic reticulum) is incorrect because the rough endoplasmic reticulum is more involved in protein synthesis and processing. Choice C (Mitochondria) is incorrect as mitochondria are primarily responsible for energy production. Choice D (Lysosomes) is incorrect because lysosomes are organelles involved in intracellular digestion and waste removal, not specifically related to detoxification.
4. In DNA, the nucleotide base adenine always binds with which of the following?
- A. Guanine
- B. Uracil
- C. Thymine
- D. Cytosine
Correct answer: C
Rationale: The correct answer is C: Thymine. In DNA, adenine always pairs with thymine, forming a base pair held together by hydrogen bonds. Guanine pairs with cytosine. Uracil is found in RNA, not DNA. Cytosine pairs with guanine. Therefore, option C is the correct pairing for adenine in DNA.
5. Which of the following organelles is the site of cellular respiration?
- A. Nucleus
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: B
Rationale: The correct answer is B: Mitochondria. Mitochondria are known as the powerhouse of the cell because they generate most of the cell's supply of ATP through cellular respiration. The other organelles listed, such as the nucleus (choice A), lysosomes (choice C), and ribosomes (choice D), do not play a direct role in cellular respiration. The nucleus contains genetic material, lysosomes are involved in digestion and waste removal, and ribosomes are responsible for protein synthesis.
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