HESI RN
Biology Practice Test
1. Which of the following provides support and shape to the cell?
- A. Microtubules
- B. Microfilaments
- C. Cilia
- D. Microvilli
Correct answer: A
Rationale: Microtubules are fundamental components of the cytoskeleton in a cell, playing a crucial role in providing structural support and maintaining the cell's shape. They are composed of tubulin protein subunits and are involved in various cellular processes like cell division, intracellular transport, and cell motility. Microfilaments, on the other hand, are involved in cell movement and maintaining cell shape but are not primarily responsible for supporting the cell's overall structure. Cilia and microvilli are cellular projections that aid in movement and absorption, respectively, but they do not play a significant role in providing structural support to the cell.
2. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?
- A. They are gathered on either side of the separating cell
- B. They are all aligned along the metaphase plate
- C. They are attached to the spindle
- D. They are visibly separate
Correct answer: D
Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.
3. What do prokaryotic cells lack in comparison to eukaryotic cells?
- A. A defined nucleus and a series of membrane-bound organelles
- B. A defined nucleus and no membrane-bound organelles
- C. No defined nucleus and a series of membrane-bound organelles
- D. No defined nucleus and no membrane-bound organelles
Correct answer: D
Rationale: Prokaryotic cells are characterized by the absence of a defined nucleus and membrane-bound organelles. Choice A is incorrect because prokaryotic cells lack membrane-bound organelles. Choice B is incorrect because prokaryotic cells lack both a defined nucleus and membrane-bound organelles. Choice C is incorrect as prokaryotic cells have no defined nucleus. Therefore, the correct answer is D.
4. What is the composition of the cellular membrane?
- A. A bilayer of phospholipid molecules
- B. A single layer of phospholipid molecules
- C. Proteins that act as transport highways
- D. Carbohydrates
Correct answer: A
Rationale: The cellular membrane is primarily composed of a phospholipid bilayer, which consists of two layers of phospholipid molecules. These molecules have a hydrophilic (water-attracting) head and hydrophobic (water-repelling) tail, creating a barrier that separates the internal cellular environment from the external surroundings. While proteins are embedded within this bilayer and act as transport channels, receptors, and structural support, carbohydrates are found on the outer surface of the membrane for cell recognition and signaling purposes. Therefore, the correct answer is a bilayer of phospholipid molecules.
5. Protein synthesis begins with a process known as transcription. Where does this process occur?
- A. In the cytoplasm
- B. In the nuclear envelope
- C. In the ribosome unit
- D. In the nucleus
Correct answer: D
Rationale: The correct answer is D: In the nucleus. Transcription, the initial step of protein synthesis, takes place in the nucleus where DNA is transcribed into mRNA. This mRNA then leaves the nucleus and enters the cytoplasm where translation occurs on the ribosomes. Choices A, B, and C are incorrect because transcription specifically occurs in the nucleus, not in the cytoplasm, nuclear envelope, or ribosome unit.
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