HESI RN
Biology Practice Test
1. What is the most significant contributor to cellular function?
- A. Proteins
- B. Phospholipids
- C. Carbohydrates
- D. Fatty acids
Correct answer: A
Rationale: The correct answer is A: Proteins. Proteins are the most significant contributor to cellular function as they play crucial roles in almost all biological processes. They act as enzymes that catalyze reactions, are involved in cell signaling pathways, and provide structural support to cells. Phospholipids (Choice B), while important for cell membrane structure, do not have the same diverse functions as proteins in cellular processes. Carbohydrates (Choice C) primarily serve as an energy source and structural components but are not as versatile in cellular functions as proteins. Fatty acids (Choice D) are essential components of cell membranes and energy storage molecules but do not have the same broad range of functions as proteins in cellular processes.
2. Who discovered the basic principles of genetics using garden peas?
- A. Curie
- B. Mendel
- C. Hawking
- D. Galileo
Correct answer: B
Rationale: The correct answer is B, Mendel. Gregor Mendel is known as the father of genetics for his groundbreaking work with pea plants. He discovered the basic principles of heredity through his experiments, establishing the foundation of modern genetics. Choice A, Curie, is incorrect as Marie Curie was a physicist and chemist known for her pioneering research on radioactivity. Choice C, Hawking, is incorrect as Stephen Hawking was a theoretical physicist known for his work on black holes and cosmology. Choice D, Galileo, is incorrect as Galileo Galilei was an astronomer and physicist renowned for his contributions to the scientific revolution, particularly in astronomy.
3. Which organelle has the ability to hydrolyze fats, nucleic acids, proteins, and sugars?
- A. Chloroplasts
- B. Mitochondria
- C. Lysosomes
- D. Ribosomes
Correct answer: C
Rationale: The correct answer is C, Lysosomes. Lysosomes contain hydrolytic enzymes that are capable of breaking down various biomolecules such as fats, nucleic acids, proteins, and sugars. This organelle acts as the 'digestive system' of the cell. Choices A, B, and D are incorrect because chloroplasts are involved in photosynthesis, mitochondria are responsible for energy production, and ribosomes are responsible for protein synthesis, not the hydrolysis of biomolecules.
4. The term pleiotropy is best defined as which of the following?
- A. A situation in which one gene remains unexpressed
- B. One gene influencing multiple, seemingly unrelated phenotypic traits
- C. Two genes affected by a single allele
- D. A condition in which multiple genes are missing
Correct answer: B
Rationale: Pleiotropy is best defined as one gene influencing multiple, seemingly unrelated phenotypic traits. This phenomenon showcases the multifunctionality of genes, where a single gene can have effects on various aspects of an organism's phenotype. Choices A, C, and D do not accurately capture the concept of pleiotropy. Option A refers to gene expression, not pleiotropy. Option C describes genetic interactions but not in the context of pleiotropy. Option D talks about missing genes, which is unrelated to the definition of pleiotropy.
5. Which of the following is not one of the four nitrogenous bases that make up the DNA structure?
- A. Adenine
- B. Guanine
- C. Uracil
- D. Thymine
Correct answer: C
Rationale: The correct answer is C: Uracil. Uracil is found in RNA, not DNA. The four nitrogenous bases in DNA are adenine, thymine, cytosine, and guanine. Choice A, Adenine, is a nitrogenous base in DNA. Choice B, Guanine, is another nitrogenous base in DNA. Choice D, Thymine, is also one of the four nitrogenous bases in DNA. Therefore, the correct answer is Uracil (Choice C).
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