HESI RN
Biology Practice Test
1. In meiosis, the chromosome number is reduced from:
- A. 46 to 23
- B. 46 to 33
- C. 28 to 14
- D. 24 to 12
Correct answer: A
Rationale: The correct answer is A: "46 to 23." In meiosis, the chromosome number is reduced by half to form gametes for sexual reproduction. In humans, where the diploid chromosome number is 46, meiosis results in haploid cells with 23 chromosomes. Choices B, C, and D are incorrect because they do not represent the correct reduction in chromosome number during meiosis.
2. Which of the following makes it possible to predict the genotype and phenotype of the offspring of sexual reproduction?
- A. Punnett square
- B. Chi-square
- C. Microscope
- D. None of these
Correct answer: A
Rationale: The correct answer is A, Punnett square. A Punnett square is a tool specifically designed to predict the genotype and phenotype combinations of offspring resulting from a particular cross or breeding experiment. It helps in understanding the probability of different genotypes and phenotypes appearing in the offspring. Choice B, Chi-square, is a statistical test used to determine if there is a significant difference between the expected frequencies and the observed frequencies in a study. Choice C, Microscope, is used for viewing tiny structures and organisms, not for predicting genetic outcomes. Choice D, None of these, is incorrect as Punnett square is a valid tool for predicting genetic outcomes in offspring.
3. Which of the following correctly identifies the two types of cells?
- A. Mitosis and meiosis
- B. Mitochondrion and chloroplast
- C. Genotype and phenotype
- D. Prokaryotic and eukaryotic
Correct answer: D
Rationale: The correct answer is D: Prokaryotic and eukaryotic. Cells are classified into two major types: prokaryotic, which lack a nucleus, and eukaryotic, which have a defined nucleus and other membrane-bound organelles. Choice A, mitosis and meiosis, refers to cell division processes. Choice B, mitochondrion and chloroplast, are cell organelles involved in energy production and photosynthesis, respectively. Choice C, genotype and phenotype, relate to genetic characteristics and physical traits, not cell types.
4. Prophase is the first stage of mitosis. Which of the following best describes chromosomes during this stage?
- A. They are gathered on either side of the separating cell
- B. They are all aligned along the metaphase plate
- C. They are attached to the spindle
- D. They are visibly separate
Correct answer: D
Rationale: The correct answer is D. During prophase, the chromosomes condense and become visible as distinct structures under a microscope. Choice A is incorrect as chromosomes are not gathered on either side of the separating cell during prophase. Choice B is incorrect because chromosomes align along the metaphase plate during the subsequent stage, metaphase. Choice C is incorrect as chromosomes become attached to the spindle fibers during prometaphase, the stage following prophase.
5. Protein synthesis begins with a process known as transcription. Where does this process occur?
- A. In the cytoplasm
- B. In the nuclear envelope
- C. In the ribosome unit
- D. In the nucleus
Correct answer: D
Rationale: The correct answer is D: In the nucleus. Transcription, the initial step of protein synthesis, takes place in the nucleus where DNA is transcribed into mRNA. This mRNA then leaves the nucleus and enters the cytoplasm where translation occurs on the ribosomes. Choices A, B, and C are incorrect because transcription specifically occurs in the nucleus, not in the cytoplasm, nuclear envelope, or ribosome unit.
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