Nursing Elites

1. What is the mechanism of action of corticotropin (Acthar) when prescribed as replacement therapy for a male client who has undergone surgical removal of a pituitary tumor?

• A. It decreases cyclic adenosine monophosphate (cAMP) production and affects the metabolic rate of target organs.
• B. It interacts with plasma membrane receptors to inhibit enzymatic actions.
• C. It interacts with plasma membrane receptors to produce enzymatic actions that affect protein, fat, and carbohydrate metabolism.
• D. It regulates the threshold for water reabsorption in the kidneys.

Correct answer: C

Rationale: Corticotropin (ACTH) stimulates the adrenal cortex to secrete cortisol and other hormones, affecting protein, fat, and carbohydrate metabolism. Choice A is incorrect because corticotropin does not decrease cAMP production; instead, it stimulates enzymatic actions. Choice B is incorrect because corticotropin does not inhibit enzymatic actions but rather produces enzymatic actions. Choice D is incorrect because corticotropin's mechanism of action does not involve regulating the threshold for water reabsorption in the kidneys.

2. A client with hyperthyroidism is prescribed radioactive iodine therapy. The nurse should monitor for which of the following potential side effects?

• A. Hypothyroidism
• B. Hyperthyroidism
• C. Hypercalcemia
• D. Hyperglycemia

Correct answer: A

Rationale: When a client with hyperthyroidism undergoes radioactive iodine therapy, the treatment aims to reduce thyroid hormone production by destroying thyroid tissue. As a result, there is a high likelihood of developing hypothyroidism as a side effect. Monitoring for hypothyroidism is crucial post-treatment. Choices B, C, and D are incorrect because the therapeutic goal is to address hyperthyroidism by inducing hypothyroidism through the treatment.

3. Why is glucose an important molecule in a cell?

• A. Extraction of energy
• B. Synthesis of protein
• C. Building of genetic material
• D. Formation of cell membranes

Correct answer: A

Rationale: Glucose is a crucial molecule in cells because it serves as the primary source of energy through cellular respiration. Choice B, the synthesis of protein, is incorrect because proteins are typically synthesized from amino acids, not glucose. Choice C, the building of genetic material, is incorrect because genetic material, such as DNA and RNA, is not directly built from glucose. Choice D, the formation of cell membranes, is also incorrect as cell membranes are primarily composed of lipids and proteins, not glucose.

4. In a client with hypoparathyroidism, the nurse should expect which laboratory result?

• A. Increased calcium levels
• B. Decreased phosphorus levels
• C. Increased phosphorus levels
• D. Increased potassium levels

Correct answer: C

Rationale: In hypoparathyroidism, there is a deficiency of parathyroid hormone, leading to decreased calcium levels and increased phosphorus levels. Therefore, the correct answer is 'Increased phosphorus levels' (Choice C). Choice A, 'Increased calcium levels,' is incorrect because hypoparathyroidism is associated with low calcium levels. Choice B, 'Decreased phosphorus levels,' is incorrect as phosphorus levels are typically elevated in hypoparathyroidism. Choice D, 'Increased potassium levels,' is not directly related to hypoparathyroidism and is not an expected laboratory result in this condition.

5. When caring for a male client with diabetes insipidus, what does Nurse Juliet expect to administer?

• A. Vasopressin (Pitressin Synthetic)
• B. Furosemide (Lasix)
• C. Regular insulin
• D. 10% dextrose

Correct answer: A

Rationale: The correct answer is A: Vasopressin (Pitressin Synthetic). Vasopressin is the treatment of choice for diabetes insipidus as it replaces the deficient antidiuretic hormone. Furosemide (Lasix) (choice B) is a diuretic and would exacerbate fluid loss, making it inappropriate for diabetes insipidus. Regular insulin (choice C) is used for diabetes mellitus, not diabetes insipidus, which involves water balance rather than glucose regulation. 10% dextrose (choice D) is used to treat hypoglycemia, not diabetes insipidus.

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