ATI LPN
Pharmacology for LPN
1. Which laboratory test should be monitored to evaluate the effectiveness of anticoagulant therapy in a client with deep vein thrombosis (DVT)?
- A. Complete blood count (CBC)
- B. Activated partial thromboplastin time (aPTT)
- C. Serum electrolytes
- D. Liver function tests
Correct answer: B
Rationale: Activated partial thromboplastin time (aPTT) is the laboratory test monitored to evaluate the effectiveness of anticoagulant therapy, particularly with heparin. It measures the time it takes for blood to clot, and monitoring aPTT helps ensure the therapeutic range is maintained to prevent clot formation and excessive bleeding. Choices A, C, and D are incorrect because a complete blood count (CBC) assesses overall health, serum electrolytes evaluate the body's electrolyte balance, and liver function tests assess liver health, none of which directly evaluate the effectiveness of anticoagulant therapy for DVT.
2. A nurse is teaching a client about the use of duloxetine. Which of the following should be included?
- A. It is an antidepressant medication
- B. It can cause weight gain
- C. Monitor for liver function
- D. It has no side effects
Correct answer: C
Rationale: The correct answer is C: 'Monitor for liver function.' Duloxetine is an antidepressant medication, not an antipsychotic, so choice A is incorrect. One of the common side effects of duloxetine is weight gain, making choice B incorrect. Choice D, stating that duloxetine has no side effects, is inaccurate as all medications have the potential for side effects. Monitoring liver function is crucial with duloxetine because it can impact liver function, emphasizing the importance of regular checks to ensure the client's safety.
3. Mucus is produced by the salivary glands and the:
- A. intestinal glands.
- B. esophageal glands.
- C. pineal gland.
- D. islets of Langerhans.
Correct answer: A
Rationale: Mucus is produced by the salivary glands to moisten food and aid in swallowing. Additionally, the intestinal glands secrete mucus to protect the lining of the intestines. The other choices, esophageal glands, pineal gland, and islets of Langerhans, are not involved in the production of mucus in the digestive system.
4. A client who is pregnant and has phenylketonuria (PKU) is receiving teaching from a nurse. Which of the following foods should the nurse instruct the client to eliminate from her diet?
- A. Peanut butter
- B. Potatoes
- C. Apple juice
- D. Broccoli
Correct answer: A
Rationale: Individuals with phenylketonuria (PKU) have difficulty breaking down phenylalanine, an amino acid found in protein-rich foods like peanut butter. Therefore, clients with PKU should avoid foods high in phenylalanine, such as peanut butter, to prevent adverse effects on their health. Choices B, C, and D are not typically high in phenylalanine and do not pose the same risk to individuals with PKU as peanut butter.
5. A 45-year-old woman presents with fatigue, pruritus, and jaundice. Laboratory tests reveal elevated bilirubin and alkaline phosphatase levels. Imaging shows a normal common bile duct but dilated intrahepatic bile ducts. What is the most likely diagnosis?
- A. Primary biliary cirrhosis
- B. Primary sclerosing cholangitis
- C. Gallstones
- D. Pancreatic cancer
Correct answer: A
Rationale: Based on the symptoms of fatigue, pruritus, and jaundice, along with elevated bilirubin and alkaline phosphatase levels, and imaging findings of a normal common bile duct but dilated intrahepatic bile ducts, the most likely diagnosis is primary biliary cirrhosis. Primary sclerosing cholangitis presents with different imaging findings, often showing strictures and beading of the bile ducts. Gallstones typically cause obstruction in the biliary system, leading to different symptoms and imaging findings. Pancreatic cancer would present with different clinical features and imaging characteristics.
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