Nursing Elites

1. Pepsinogen secreted by the gastric cells is converted into pepsin by:

• A. enterokinase
• B. hydrochloric acid
• C. gastric lipase
• D. pancreatic lipase

Correct answer: B

Rationale: Pepsinogen is converted into its active form, pepsin, by hydrochloric acid in the stomach. Hydrochloric acid helps in unfolding the pepsinogen molecule to transform it into pepsin, which is crucial for protein digestion. Therefore, the correct answer is hydrochloric acid (choice B). Enterokinase (choice A) is an enzyme produced in the small intestine that activates trypsinogen into trypsin, not pepsinogen. Gastric lipase (choice C) is an enzyme that digests fats, not involved in converting pepsinogen to pepsin. Pancreatic lipase (choice D) is an enzyme produced by the pancreas that aids in breaking down fats in the small intestine, not part of the process of pepsin activation.

2. What substance activates pepsinogen to pepsin?

• A. Bile
• B. Gastrin
• C. Secretin
• D. Hydrochloric acid

Correct answer: D

Rationale: The correct answer is D: Hydrochloric acid. Hydrochloric acid in the stomach plays a crucial role in converting pepsinogen into its active form, pepsin, which is necessary for digesting proteins. Bile (Choice A) is involved in the emulsification of fats, not in the activation of pepsinogen. Gastrin (Choice B) is a hormone that stimulates the secretion of gastric acid but does not directly activate pepsinogen. Secretin (Choice C) is a hormone that regulates the pH of the duodenum but is not responsible for the activation of pepsinogen.

3. How is the enzyme trypsin activated?

• A. By zymogen.
• B. By bile.
• C. By gastrin.
• D. By enterokinase.

Correct answer: D

Rationale: The correct answer is D: By enterokinase. Trypsin is activated by enterokinase, an enzyme secreted by the small intestine. Enterokinase plays a crucial role in converting trypsinogen into its active form, trypsin. Choices A, B, and C are incorrect because trypsin is specifically activated by enterokinase, not by zymogen, bile, or gastrin.

4. Which component of fat can be used to make glucose through gluconeogenesis?

• A. Glycogen
• B. Fatty acids
• C. Glycerol
• D. Monoglyceride

Correct answer: C

Rationale: The correct answer is 'Glycerol.' Glycerol, a component of fat, can be converted into glucose through gluconeogenesis. Glycogen (Choice A) is a polysaccharide stored in animals, not a component of fat. Fatty acids (Choice B) are used primarily for energy production through beta-oxidation, not for gluconeogenesis. Monoglyceride (Choice D) is a molecule formed during fat digestion, but it is not the component of fat that can be used to make glucose.

5. Which of the following is one of the simplest amino acids?

• A. Arginine
• B. Valine
• C. Lysine
• D. Glycine

Correct answer: D

Rationale: The correct answer is Glycine. Glycine is indeed one of the simplest amino acids as it consists of just a hydrogen atom as its side chain. Arginine, Valine, and Lysine are all more complex amino acids compared to Glycine, making them incorrect choices for this question.

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