ATI LPN
LPN Pharmacology Assessment A
1. A client with atrial fibrillation is receiving warfarin (Coumadin). The nurse should monitor which laboratory test to determine the effectiveness of the therapy?
- A. Prothrombin time (PT) and international normalized ratio (INR)
- B. Activated partial thromboplastin time (aPTT)
- C. Complete blood count (CBC)
- D. Fibrinogen level
Correct answer: A
Rationale: To monitor the effectiveness of warfarin therapy in a client with atrial fibrillation, the nurse should assess the Prothrombin time (PT) and international normalized ratio (INR) levels. These tests help determine the clotting ability of the blood and ensure that the client's anticoagulation levels are within the therapeutic range, reducing the risk of bleeding or clotting complications. Activated partial thromboplastin time (aPTT) (Choice B) is more commonly used to monitor heparin therapy. Complete blood count (CBC) (Choice C) provides information about the cellular components of blood but does not directly assess the effectiveness of warfarin therapy. Fibrinogen level (Choice D) is not typically used to monitor warfarin therapy; it reflects the level of fibrinogen in the blood, which is involved in the clotting process.
2. A client has a new prescription for prednisone. Which of the following statements should the nurse include in the teaching?
- A. You may experience weight gain.
- B. Increase your intake of vitamin K.
- C. Expect increased urinary output.
- D. You may have dark, tarry stools.
Correct answer: A
Rationale: The correct answer is A: 'You may experience weight gain.' Prednisone commonly causes weight gain as a side effect, so it is important for the client to be aware of this potential outcome. Monitoring weight changes can be essential in managing the medication's effects and overall health. Choices B, C, and D are incorrect. Increasing vitamin K intake is not specifically related to prednisone use. Expecting increased urinary output is not a common side effect of prednisone. Dark, tarry stools are more commonly associated with gastrointestinal bleeding rather than prednisone use.
3. A client has a history of left-sided heart failure. The nurse should look for the presence of which finding to determine whether the problem is currently active?
- A. Presence of ascites
- B. Bilateral lung crackles
- C. Jugular vein distention
- D. Pedal edema bilaterally
Correct answer: B
Rationale: When assessing a client with a history of left-sided heart failure, the presence of bilateral lung crackles is a key finding to determine if the condition is currently active. Crackles in the lungs indicate fluid accumulation, a common sign of left-sided heart failure due to pulmonary congestion. Choices A, C, and D are incorrect because ascites, jugular vein distention, and pedal edema are more commonly associated with right-sided heart failure.
4. The client is receiving heparin therapy for deep vein thrombosis (DVT). Which lab test should be monitored to evaluate the effectiveness of heparin?
- A. Prothrombin time (PT)
- B. International normalized ratio (INR)
- C. Activated partial thromboplastin time (aPTT)
- D. Fibrinogen levels
Correct answer: C
Rationale: Activated partial thromboplastin time (aPTT) is the appropriate lab test to monitor the therapeutic effectiveness of heparin therapy. Heparin affects the intrinsic pathway of the coagulation cascade, and monitoring aPTT helps ensure the client is within the therapeutic range to prevent clot formation. Prothrombin time (PT) and International normalized ratio (INR) are used to monitor warfarin therapy, a different anticoagulant that affects the extrinsic pathway of the coagulation cascade. Fibrinogen levels are not specific to monitoring heparin therapy.
5. When educating a client with a new prescription for nitroglycerin, which of the following instructions should the nurse include?
- A. Store the medication in a cool, dark place.
- B. Take the medication before bedtime.
- C. Take the medication with food.
- D. Take the medication at the first sign of chest pain.
Correct answer: D
Rationale: The correct instruction for a client with a new prescription for nitroglycerin is to take the medication at the first sign of chest pain. Nitroglycerin is a vasodilator used to relieve chest pain associated with angina. Taking it at the onset of chest pain ensures prompt relief by dilating blood vessels and increasing blood flow to the heart muscle. Storing nitroglycerin in a cool, dark place helps maintain its potency, while taking it with food can alter its absorption. Timing the medication with bedtime is not necessary, but prompt administration at the first sign of chest pain is crucial for effective management of angina. Choices A, B, and C are incorrect because storing the medication in a cool, dark place, taking it before bedtime, and taking it with food are not essential instructions for nitroglycerin use. The priority is to administer it promptly when chest pain occurs to achieve optimal therapeutic effects.
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