ATI LPN
LPN Pharmacology Practice Questions
1. A client with a history of atrial fibrillation is prescribed warfarin (Coumadin). Which laboratory value should the nurse monitor to assess the effectiveness of the medication?
- A. Activated partial thromboplastin time (aPTT)
- B. Prothrombin time (PT) and international normalized ratio (INR)
- C. Platelet count
- D. Erythrocyte sedimentation rate (ESR)
Correct answer: B
Rationale: Prothrombin time (PT) and international normalized ratio (INR) are the laboratory values used to monitor the effectiveness of warfarin therapy. These values help ensure that the client is within the therapeutic range for anticoagulation. PT measures the time it takes for blood to clot, while INR standardizes PT results to minimize variations between laboratories. Monitoring these values is crucial to prevent complications such as bleeding or clot formation. Activated partial thromboplastin time (aPTT) (Choice A) is more commonly used to monitor heparin therapy. Platelet count (Choice C) assesses the number of platelets in the blood and is not specific to warfarin therapy. Erythrocyte sedimentation rate (ESR) (Choice D) is a non-specific marker of inflammation and is not used to monitor the effectiveness of warfarin therapy.
2. A client has a new prescription for rifampin. Which of the following instructions should the nurse include?
- A. Take the medication with food.
- B. Expect red-orange discoloration of body fluids.
- C. Monitor for signs of hyperglycemia.
- D. Avoid consuming dairy products.
Correct answer: B
Rationale: The correct answer is to inform the client to expect red-orange discoloration of body fluids when taking rifampin. Rifampin is known to cause this side effect, which is harmless but can be surprising to patients. It is important for the nurse to educate the client about this expected change to prevent unnecessary concern or alarm. Monitoring for hyperglycemia is not directly related to rifampin, and taking the medication with food or avoiding dairy products are not specific instructions for this medication.
3. During an assessment, a client taking valproic acid exhibits elevated liver enzymes. What finding should the nurse report to the provider?
- A. Elevated liver enzymes
- B. Weight loss
- C. Dry mouth
- D. Increased appetite
Correct answer: A
Rationale: Elevated liver enzymes are a critical finding that the nurse should report to the provider when assessing a client taking valproic acid. It can be indicative of hepatotoxicity, a severe side effect associated with valproic acid use. Timely reporting and intervention are essential to prevent further complications and ensure the client's safety and well-being. Choices B, C, and D are not directly related to valproic acid use or the manifestation of hepatotoxicity. Weight loss, dry mouth, and increased appetite are not typically associated with elevated liver enzymes in the context of valproic acid administration.
4. A client with a diagnosis of myocardial infarction has a new activity prescription allowing the client to have bathroom privileges. As the client stands and begins to walk, the client begins to complain of chest pain. The nurse should take which action?
- A. Assist the client to get back into bed.
- B. Report the chest pain episode to the healthcare provider.
- C. Tell the client to stand still and take the client's blood pressure.
- D. Give a nitroglycerin (Nitrostat) tablet and assist the client to the bathroom.
Correct answer: A
Rationale: In a client with myocardial infarction experiencing chest pain during activity, the priority action is to stop the activity immediately to reduce the heart's workload and oxygen demand. Assisting the client back to bed helps in reducing stress on the heart and can prevent worsening of the condition. Reporting the chest pain episode to the healthcare provider is important but should not delay taking immediate action to alleviate symptoms. Taking the client's blood pressure and administering nitroglycerin are secondary actions after ensuring the client's safety and comfort. Therefore, the correct action is to assist the client back into bed.
5. The client needs instruction on using a metered-dose inhaler (MDI). Which instruction should be given?
- A. Inhale the medication and then exhale immediately
- B. Exhale fully, then place the inhaler in your mouth and inhale deeply while pressing the canister
- C. Take two short breaths before inhaling the medication
- D. Hold your breath for 5 seconds after inhaling the medication
Correct answer: B
Rationale: The correct technique for using a metered-dose inhaler (MDI) involves exhaling fully before inhaling deeply while pressing the canister to ensure effective delivery of the medication. Choice A is incorrect as exhaling should precede inhaling. Choice C is incorrect as taking two short breaths is not part of the correct technique. Choice D is incorrect as there is no need to hold the breath for a specific time after inhaling the medication.
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