Nursing Elites

1. The hormone secretin stimulates production of a buffering solution for the duodenum by the:

• A. stomach.
• B. liver.
• C. pancreas.
• D. oxyntic cells.

Correct answer: C

Rationale: The correct answer is C: pancreas. Secretin stimulates the pancreas to release bicarbonate, which acts as a buffering solution to neutralize the acid entering the duodenum from the stomach. This process helps in maintaining the pH balance in the small intestine. Choice A, stomach, is incorrect as the stomach does not produce the buffering solution needed for the duodenum. Choice B, liver, is incorrect because secretin does not directly stimulate the liver to produce a buffering solution. Choice D, oxyntic cells, is also incorrect as these cells in the stomach are responsible for producing gastric acid, not the buffering solution needed in the duodenum.

2. What substance activates pepsinogen to pepsin?

• A. Bile
• B. Gastrin
• C. Secretin
• D. Hydrochloric acid

Correct answer: D

Rationale: The correct answer is D: Hydrochloric acid. Hydrochloric acid in the stomach plays a crucial role in converting pepsinogen into its active form, pepsin, which is necessary for digesting proteins. Bile (Choice A) is involved in the emulsification of fats, not in the activation of pepsinogen. Gastrin (Choice B) is a hormone that stimulates the secretion of gastric acid but does not directly activate pepsinogen. Secretin (Choice C) is a hormone that regulates the pH of the duodenum but is not responsible for the activation of pepsinogen.

3. After absorption, the end products of carbohydrate and protein digestion enter the:

• A. enterohepatic circulation.
• B. gastrointestinal circulation.
• C. common bile duct.
• D. portal blood system.

Correct answer: D

Rationale: The correct answer is D: portal blood system. After absorption, carbohydrates and proteins are transported via the portal blood system to the liver for further processing and distribution to the rest of the body. Choices A, B, and C are incorrect. Enterohepatic circulation refers to the recycling of compounds between the liver and the intestines, not the direct route for absorbed nutrients. Gastrointestinal circulation is a vague and non-specific term, not specifically related to the transport of absorbed nutrients. The common bile duct is involved in transporting bile from the liver and gallbladder to the small intestine, not the end products of carbohydrate and protein digestion.

4. Where does gluconeogenesis occur?

• A. Muscles.
• B. Pancreas.
• C. Liver.
• D. Spleen.

Correct answer: C

Rationale: Gluconeogenesis mainly occurs in the liver. It is a process where glucose is synthesized from non-carbohydrate sources such as amino acids and glycerol. The liver is the primary site for gluconeogenesis due to the presence of key enzymes and substrates required for this process. Muscles do not play a significant role in gluconeogenesis, making choice A incorrect. The pancreas is involved in the regulation of blood sugar levels through insulin and glucagon but is not the primary site for gluconeogenesis, so choice B is incorrect. The spleen is not a major organ involved in glucose metabolism, making choice D incorrect.

5. Which phase of metabolism makes growth and repair possible?

• A. digestion
• B. catabolism
• C. anabolism
• D. ketosis

Correct answer: C

Rationale: Anabolism is the phase of metabolism responsible for building up and repairing tissues in the body. It involves processes that require energy to synthesize complex molecules from simpler ones. Digestion (choice A) is the process of breaking down food into simpler substances for absorption. Catabolism (choice B) involves the breakdown of complex molecules into simpler ones with the release of energy. Ketosis (choice D) is a metabolic state where the body uses fat as the primary source of energy, which is not directly related to growth and repair.

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