HESI A2
HESI A2 Practice Test Biology
1. Which organelle contains the genetic material of the cell?
- A. Golgi apparatus
- B. Ribosome
- C. Endoplasmic reticulum
- D. Nucleus
Correct answer: D
Rationale: The correct answer is 'D: Nucleus.' The nucleus is the organelle that contains the cell's genetic material, which is the DNA. The genetic material in the nucleus controls the cell's activities and plays a crucial role in inheritance. Choices A, B, and C are incorrect because the Golgi apparatus is involved in modifying, sorting, and packaging of proteins; ribosomes are involved in protein synthesis; and endoplasmic reticulum is involved in protein and lipid synthesis and transportation, but none of them contain the genetic material of the cell.
2. Which organelle is responsible for making proteins?
- A. Ribosome
- B. Chloroplast
- C. Lysosome
- D. Mitochondrion
Correct answer: A
Rationale: Ribosomes are the organelles responsible for protein synthesis within the cell. They are the sites where amino acids are linked together to form proteins based on the instructions carried by mRNA (messenger RNA). Ribosomes can be found free-floating in the cytoplasm or attached to the endoplasmic reticulum, and they play a crucial role in translating genetic information into proteins. Chloroplasts are responsible for photosynthesis, lysosomes are involved in digestion and waste removal, and mitochondria are known as the powerhouse of the cell responsible for energy production through cellular respiration. Therefore, the ribosome is the correct organelle responsible for making proteins.
3. A cell that does not contain membrane-bound organelles or a defined nucleus would be classified as:
- A. eukaryotic
- B. embryonic
- C. prokaryotic
- D. symbiotic
Correct answer: C
Rationale: A cell that does not contain membrane-bound organelles or a defined nucleus is classified as prokaryotic. Prokaryotic cells lack a true nucleus, and their genetic material is typically found in a region called the nucleoid. Examples of prokaryotic organisms include bacteria and archaea. Eukaryotic cells, on the other hand, contain membrane-bound organelles and a true nucleus, distinguishing them from prokaryotic cells. Embryonic and symbiotic classifications are not directly related to the presence of organelles or a nucleus in cells.
4. Which is a byproduct of fermentation in muscle cells?
- A. Ethanol
- B. Pyruvic acid
- C. Lactic acid
- D. Oxygen
Correct answer: C
Rationale: Lactic acid is a byproduct of fermentation in muscle cells. During intense exercise or when oxygen is limited, muscle cells use anaerobic respiration to generate energy. This process breaks down glucose into lactic acid, which can cause muscle fatigue and soreness. Choice A, Ethanol, is not produced in muscle cells during fermentation. Choice B, Pyruvic acid, is an intermediate product in glucose metabolism but is not a byproduct of fermentation in muscle cells. Choice D, Oxygen, is not a byproduct of fermentation but a reactant in aerobic respiration.
5. During which phase of mitosis do the chromosomes align in the center of the cell?
- A. Prophase
- B. Metaphase
- C. Telophase
- D. Anaphase
Correct answer: B
Rationale: The correct answer is Metaphase. During Metaphase, the chromosomes line up along the center of the cell's equator, forming the metaphase plate. This alignment ensures that during the subsequent phase, Anaphase, the sister chromatids can separate and move towards opposite poles. Prophase is the initial phase of mitosis where chromosomes condense and the nuclear envelope breaks down. Telophase is the final phase of mitosis where two new nuclei form.
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