HESI A2
Biology HESI A2 2024
1. In a strand of DNA, you would expect to see adenine paired with ___________.
- A. cytosine
- B. uracil
- C. thymine
- D. guanine
Correct answer: C
Rationale: In a strand of DNA, adenine always pairs with thymine through two hydrogen bonds. This pairing is a fundamental aspect of DNA structure, where adenine and thymine complement each other in the double helix. Choice A (cytosine) is incorrect because adenine does not pair with cytosine in DNA. Choice B (uracil) is incorrect as uracil is found in RNA, not DNA. Choice D (guanine) is incorrect as guanine pairs with cytosine, not adenine, in DNA.
2. Which is an example of a gymnosperm?
- A. Red cedar
- B. Japanese cherry
- C. Flowering dogwood
- D. American chestnut
Correct answer: A
Rationale: Red cedar is the correct answer as it is an example of a gymnosperm. Gymnosperms are plants that produce seeds not enclosed within an ovary or fruit. In the case of red cedar, it belongs to the gymnosperm group and has naked seeds that are exposed on the surface of scales or leaves. Choices B, C, and D are angiosperms, not gymnosperms. Japanese cherry, flowering dogwood, and American chestnut are all examples of angiosperms, which are flowering plants with seeds enclosed within an ovary.
3. Which statement is true of enzymes?
- A. They are made from lipids.
- B. They are made from proteins.
- C. They form double chains of DNA.
- D. They bind with catalysts.
Correct answer: B
Rationale: The correct answer is B: Enzymes are made from proteins. Enzymes are biological molecules that act as catalysts to speed up chemical reactions in living organisms. While the majority of enzymes are proteins, a few are made from RNA. The statement that enzymes are made from lipids (choice A) is incorrect. Enzymes do not form double chains of DNA (choice C) as their primary function is not related to DNA structure. Additionally, enzymes themselves do not bind with catalysts (choice D); instead, they act as catalysts to facilitate reactions.
4. DNA bases include all but which of the following?
- A. Adenine
- B. Thymine
- C. Uracil
- D. Cytosine
Correct answer: C
Rationale: The correct answer is C: Uracil. Uracil is not a DNA base; it is a base found only in RNA. The four bases in DNA are Adenine, Thymine, Cytosine, and Guanine. Choice A, Adenine, is a correct DNA base. Choice B, Thymine, is a correct DNA base. Choice D, Cytosine, is a correct DNA base. Therefore, Uracil is the only incorrect choice among the options provided.
5. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
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