HESI A2
Biology HESI A2 2024
1. In a strand of DNA, you would expect to see adenine paired with ___________.
- A. cytosine
- B. uracil
- C. thymine
- D. guanine
Correct answer: C
Rationale: In a strand of DNA, adenine always pairs with thymine through two hydrogen bonds. This pairing is a fundamental aspect of DNA structure, where adenine and thymine complement each other in the double helix. Choice A (cytosine) is incorrect because adenine does not pair with cytosine in DNA. Choice B (uracil) is incorrect as uracil is found in RNA, not DNA. Choice D (guanine) is incorrect as guanine pairs with cytosine, not adenine, in DNA.
2. What is the initial step in the metabolism of food to cellular energy?
- A. Citric Acid Cycle
- B. Glycolysis
- C. Electron Transport Chain
- D. Photosynthesis
Correct answer: B
Rationale: The correct answer is B: Glycolysis. Glycolysis is the initial step in the metabolism of food to cellular energy. During glycolysis, glucose is broken down into pyruvate, generating ATP and NADH. Choices A, C, and D are incorrect because the Citric Acid Cycle and Electron Transport Chain occur later in cellular respiration, while Photosynthesis is the process by which plants convert light energy into chemical energy.
3. How should a researcher test the hypothesis that eating chocolate leads to acne in teenagers?
- A. Take 100 teenagers and feed each one a different amount of chocolate daily for 60 days; then test for acne.
- B. Take 100 teenagers and feed 50 two bars of chocolate daily for 60 days while the other 50 eat no chocolate; then test for acne.
- C. Take 1 teenager and feed him or her two bars of chocolate for 30 days and no chocolate for 30 days; then test for acne.
- D. Take 100 teenagers and feed them no chocolate for 30 days and two bars of chocolate apiece for 30 days; then test for acne.
Correct answer: B
Rationale: Option B is the correct approach to test the hypothesis that eating chocolate leads to acne in teenagers. This method involves having a control group (50 teenagers not consuming chocolate) and an experimental group (50 teenagers consuming two bars of chocolate daily), which allows for comparison. By having two distinct groups, researchers can assess the impact of chocolate consumption on acne development. Option A lacks a control group for comparison, making it harder to attribute any observed effects specifically to chocolate consumption. Option C only involves a single subject, which limits the generalizability of the results. Option D, where all teenagers experience both conditions, does not allow for a direct comparison between chocolate consumption and acne development, as all subjects are exposed to both conditions.
4. What is the term for the breakdown of glycogen into glucose subunits?
- A. Hydrolysis
- B. Reduction
- C. Metabolism
- D. Transpiration
Correct answer: A
Rationale: Hydrolysis is the term used to describe the breakdown of large molecules into smaller units by adding water. In the case of glycogen being broken down into glucose subunits, this process involves the addition of water molecules to break the glycosidic bonds between glucose molecules, resulting in the release of individual glucose subunits. This process is crucial for providing cells with a source of energy when needed. Choice B, Reduction, refers to a chemical reaction involving a gain of electrons or a decrease in oxidation state, not the breakdown of glycogen into glucose subunits. Choice C, Metabolism, is a broad term encompassing all biochemical processes in an organism, including anabolism and catabolism, but does not specifically describe the breakdown of glycogen into glucose subunits. Choice D, Transpiration, is the process of water movement through a plant and is not related to the breakdown of glycogen into glucose subunits.
5. What is necessary for active transport through a membrane to take place?
- A. Glucose
- B. Oxygen
- C. Sodium
- D. ATP
Correct answer: D
Rationale: Active transport through a membrane requires energy in the form of ATP (adenosine triphosphate). ATP provides the necessary energy for the transport proteins to move molecules against the concentration gradient, from an area of lower concentration to higher concentration. This process is essential for maintaining cellular functions and regulating the internal environment of a cell. Glucose, oxygen, and sodium are important molecules involved in various cellular processes, but they are not the primary energy source required for active transport across membranes. Therefore, the correct answer is ATP.
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