HESI A2
HESI A2 Biology Practice Test
1. Which of the following shows how information is transformed to make a protein?
- A. DNA-RNA-protein
- B. gene-chromosome-protein
- C. ATP-amino acid-protein
- D. RNA-DNA-protein
Correct answer: A
Rationale: The correct sequence of events for protein synthesis is that DNA is transcribed into RNA, which is then translated into a protein. This process is known as the central dogma of molecular biology. In this sequence, DNA serves as the template for RNA synthesis (transcription), and the RNA serves as the template for protein synthesis (translation). Choice B is incorrect as genes are segments of DNA that code for proteins, and chromosomes are structures that contain DNA. Choice C is incorrect as ATP is an energy molecule and amino acids are the building blocks of proteins, but they are not directly involved in the synthesis process. Choice D is incorrect because RNA is first transcribed from DNA and then used as a template to produce proteins.
2. What is the binding membrane of an animal cell called?
- A. Biological membrane
- B. Cell coat
- C. Unit membrane
- D. Plasma membrane
Correct answer: D
Rationale: The correct answer is D: Plasma membrane. The plasma membrane surrounds the cell and acts as an interface between the living interior of the cell and the nonliving exterior. It plays a vital role in maintaining the cell's integrity, regulating the passage of substances in and out of the cell, and facilitating communication with other cells. Choices A, B, and C are incorrect because the term 'plasma membrane' specifically refers to the binding membrane of an animal cell, distinguishing it from other types of membranes or coatings found in cells.
3. Which of the following types of hormones can diffuse through the cell membrane to bind to receptors inside the cell and stimulate a chemical response to a target cell?
- A. fat-soluble hormones
- B. amino acid derivatives
- C. hydrophilic hormones
- D. water-soluble hormones
Correct answer: A
Rationale: The correct answer is A: fat-soluble hormones. Fat-soluble hormones are able to diffuse through the cell membrane to bind to receptors inside the cell. This is because they are lipophilic, allowing them to cross the lipid bilayer easily. Once inside the cell, fat-soluble hormones can directly affect gene expression or cell function. Choice B, amino acid derivatives, and choice C, hydrophilic hormones, are not able to diffuse through the cell membrane as they are not lipophilic. Therefore, they cannot bind to receptors inside the cell. Choice D, water-soluble hormones, also cannot diffuse through the cell membrane as it is hydrophilic, making it unable to reach receptors inside the cell.
4. Which of the following bases is not present in RNA?
- A. Adenine
- B. Thymine
- C. Uracil
- D. Cytosine
Correct answer: B
Rationale: Thymine is not present in RNA. RNA uses uracil as one of its bases, which pairs with adenine. In RNA, adenine does not pair with thymine as in DNA. Cytosine and guanine are the other two bases found in both RNA and DNA.
5. Which one of the following best describes the function of a cell membrane?
- A. It controls the substances entering and leaving the cell.
- B. It maintains the cell's shape.
- C. It controls the substances entering the cell.
- D. It supports the cell's structures.
Correct answer: A
Rationale: The correct answer is A. The function of a cell membrane is to control the substances entering and leaving the cell. The cell membrane is selectively permeable, allowing it to regulate the movement of ions and molecules in and out of the cell to maintain internal balance and proper function. Choice B is incorrect because while the cell membrane does provide some structural support, its primary function is not to maintain the cell's shape. Choice C is incorrect because the cell membrane controls both the substances entering and leaving the cell, not just those entering. Choice D is incorrect as the primary function of the cell membrane is not to support the cell's structures but to regulate the movement of substances.
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