HESI A2
HESI A2 Biology 2024
1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
2. What is necessary for active transport through a membrane to take place?
- A. Glucose
- B. Oxygen
- C. Sodium
- D. ATP
Correct answer: D
Rationale: Active transport through a membrane requires energy in the form of ATP (adenosine triphosphate). ATP provides the necessary energy for the transport proteins to move molecules against the concentration gradient, from an area of lower concentration to higher concentration. This process is essential for maintaining cellular functions and regulating the internal environment of a cell. Glucose, oxygen, and sodium are important molecules involved in various cellular processes, but they are not the primary energy source required for active transport across membranes. Therefore, the correct answer is ATP.
3. Which organelle is the site of energy production?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: A
Rationale: The correct answer is A: Mitochondrion. The mitochondrion is the site of energy production in a cell. It is often referred to as the powerhouse of the cell because it is where cellular respiration occurs, generating energy in the form of adenosine triphosphate (ATP) through processes like the citric acid cycle and oxidative phosphorylation. The other organelles listed play different roles in the cell - vacuoles store materials, the cell membrane regulates the movement of substances in and out of the cell, and ribosomes are involved in protein synthesis.
4. Which is a byproduct of fermentation in muscle cells?
- A. Ethanol
- B. Pyruvic acid
- C. Lactic acid
- D. Oxygen
Correct answer: C
Rationale: Lactic acid is a byproduct of fermentation in muscle cells. During intense exercise or when oxygen is limited, muscle cells use anaerobic respiration to generate energy. This process breaks down glucose into lactic acid, which can cause muscle fatigue and soreness. Choice A, Ethanol, is not produced in muscle cells during fermentation. Choice B, Pyruvic acid, is an intermediate product in glucose metabolism but is not a byproduct of fermentation in muscle cells. Choice D, Oxygen, is not a byproduct of fermentation but a reactant in aerobic respiration.
5. Two organisms live in a relationship from which both benefit. What is this called?
- A. Mutualism
- B. Parasitism
- C. Commensalism
- D. Competition
Correct answer: A
Rationale: Mutualism is a type of symbiotic relationship between two organisms in which both parties benefit from the association. It is a mutually beneficial interaction where both organisms gain something valuable, such as food, protection, or some other resource. This contrasts with parasitism, where one organism benefits at the expense of the other, commensalism, where one organism benefits while the other is unaffected, and competition, where both organisms are negatively affected by their interaction.
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