HESI A2
HESI A2 Biology Practice Test
1. Select the option that best shows complementary base pairing in DNA:
- A. A and G
- B. A and C
- C. A and A
- D. A and T
Correct answer: D
Rationale: The correct answer is D. A purine (A) must pair with a pyrimidine (T) in DNA. This eliminates options A and C as they do not follow the rule of complementary base pairing. Adenine (A) always pairs with thymine (T) due to their specific shape and bonding properties in DNA structure. Choice B is incorrect because adenine does not pair with cytosine in DNA.
2. What is the initial step in the metabolism of food to cellular energy?
- A. Citric Acid Cycle
- B. Glycolysis
- C. Electron Transport Chain
- D. Photosynthesis
Correct answer: B
Rationale: The correct answer is B: Glycolysis. Glycolysis is the initial step in the metabolism of food to cellular energy. During glycolysis, glucose is broken down into pyruvate, generating ATP and NADH. Choices A, C, and D are incorrect because the Citric Acid Cycle and Electron Transport Chain occur later in cellular respiration, while Photosynthesis is the process by which plants convert light energy into chemical energy.
3. The phases of mitosis include:
- A. Prophase, interphase, metaphase, anaphase, and telophase
- B. Prophase, prophase, metaphase, anaphase, and cytokinesis
- C. Prophase, prometaphase, metaphase, anaphase, and telophase
- D. Prophase, interphase, prophase, anaphase, and telophase
Correct answer: C
Rationale: The correct phases of mitosis are prophase, prometaphase, metaphase, anaphase, and telophase. Prophase is the first phase where chromatin condenses into chromosomes, the nuclear envelope breaks down, and the mitotic spindle forms. Prometaphase follows prophase, involving the full disintegration of the nuclear envelope and the attachment of spindle fibers to the kinetochores of the chromosomes. Metaphase is where chromosomes align along the metaphase plate. Anaphase is the phase where sister chromatids separate and move towards opposite poles. Telophase marks the final stage of mitosis, involving the decondensation of chromosomes and the reformation of the nuclear envelope. Choice A is incorrect because it includes interphase, which is not a phase of mitosis. Choice B is incorrect as it repeats prophase, which is the initial phase. Choice D is incorrect because it includes interphase and repeats prophase.
4. What type of cells possess a cell membrane?
- A. Prokaryotic cells only
- B. Eukaryotic cells only
- C. Both prokaryotic and eukaryotic cells
- D. None of the above
Correct answer: C
Rationale: Cell membranes are present in both prokaryotic and eukaryotic cells. The cell membrane serves as a barrier that encloses the cell contents and regulates the entry and exit of substances in and out of the cell. It is a fundamental structure found in all types of cells, regardless of whether they are prokaryotic (lacking a nucleus) or eukaryotic (containing a nucleus). Choice A is incorrect because eukaryotic cells also possess cell membranes. Choice B is incorrect as prokaryotic cells, such as bacteria, also have cell membranes. Choice D is incorrect as both prokaryotic and eukaryotic cells have cell membranes.
5. What is necessary for active transport through a membrane to take place?
- A. Glucose
- B. Oxygen
- C. Sodium
- D. ATP
Correct answer: D
Rationale: Active transport through a membrane requires energy in the form of ATP (adenosine triphosphate). ATP provides the necessary energy for the transport proteins to move molecules against the concentration gradient, from an area of lower concentration to higher concentration. This process is essential for maintaining cellular functions and regulating the internal environment of a cell. Glucose, oxygen, and sodium are important molecules involved in various cellular processes, but they are not the primary energy source required for active transport across membranes. Therefore, the correct answer is ATP.
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