HESI A2
HESI A2 Biology Practice Test 2024
1. What is the fundamental unit of life?
- A. Atom
- B. Cell
- C. Tissue
- D. Organ
Correct answer: B
Rationale: The correct answer is 'B: Cell.' Cells are indeed the fundamental unit of life as they are responsible for all living functions, including growth, reproduction, and maintaining homeostasis. While atoms are the basic building blocks of matter, cells are the smallest structural and functional unit of living organisms. Choices C and D, tissue and organ respectively, are composed of multiple cells working together and are not considered the basic unit of life.
2. Select the option that best shows complementary base pairing in DNA:
- A. A and G
- B. A and C
- C. A and A
- D. A and T
Correct answer: D
Rationale: The correct answer is D. A purine (A) must pair with a pyrimidine (T) in DNA. This eliminates options A and C as they do not follow the rule of complementary base pairing. Adenine (A) always pairs with thymine (T) due to their specific shape and bonding properties in DNA structure. Choice B is incorrect because adenine does not pair with cytosine in DNA.
3. What helps the cell maintain its shape and allows it to adapt?
- A. Microfilaments
- B. Cytoplasm
- C. Cytoskeleton
- D. Centrioles
Correct answer: C
Rationale: The cytoskeleton is the correct answer. It provides structural support to the cell, helps maintain its shape, and enables it to adapt to different environments. Microfilaments are part of the cytoskeleton, but they alone do not encompass the entire cytoskeleton's functions. Cytoplasm is the fluid inside the cell where organelles are suspended and is not directly responsible for maintaining cell shape. Centrioles are involved in cell division and do not primarily contribute to maintaining the cell's shape and adaptation.
4. The sum of all chemical reactions that occur in an organism is:
- A. product
- B. respiration
- C. metabolism
- D. synthesis
Correct answer: C
Rationale: Metabolism is the sum of all chemical reactions that occur within an organism to maintain life. It involves all the processes that break down molecules to release energy (catabolism) and build new molecules to support growth and maintenance (anabolism). Respiration refers specifically to the process of generating energy from the breakdown of glucose molecules. Synthesis is the creation of complex molecules from simpler ones. Therefore, metabolism is the most comprehensive term that encompasses all these processes within an organism.
5. Which of the following shows how information is transformed to make a protein?
- A. DNA-RNA-protein
- B. gene-chromosome-protein
- C. ATP-amino acid-protein
- D. RNA-DNA-protein
Correct answer: A
Rationale: The correct sequence of events for protein synthesis is that DNA is transcribed into RNA, which is then translated into a protein. This process is known as the central dogma of molecular biology. In this sequence, DNA serves as the template for RNA synthesis (transcription), and the RNA serves as the template for protein synthesis (translation). Choice B is incorrect as genes are segments of DNA that code for proteins, and chromosomes are structures that contain DNA. Choice C is incorrect as ATP is an energy molecule and amino acids are the building blocks of proteins, but they are not directly involved in the synthesis process. Choice D is incorrect because RNA is first transcribed from DNA and then used as a template to produce proteins.
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