which of the following is true of glycolysis

HESI A2

HESI A2 Biology Practice Test

1. Which of the following is true of Glycolysis?

A. It requires the absence of Oxygen
B. It occurs in the presence of Oxygen
C. It is the final step of fermentation
D. It is the final step of anaerobic respiration

Correct answer: B

Rationale: Glycolysis is the first step in cellular respiration and can occur in both aerobic (presence of oxygen) and anaerobic (absence of oxygen) conditions. In aerobic respiration, glycolysis takes place in the presence of oxygen and continues with the Krebs cycle and the electron transport chain. So, glycolysis does not require the absence of oxygen but can occur in its presence as part of the overall process of aerobic respiration. Choice A is incorrect because glycolysis can occur in the presence of oxygen. Choice C is incorrect because glycolysis is not the final step of fermentation; it is the initial step. Choice D is incorrect because glycolysis is not the final step of anaerobic respiration; it is the first step, followed by further processes to complete anaerobic respiration.

2. What happens to glucose during glycolysis?

A. Its energy is entirely lost.
B. It splits into molecules of pyruvic acid.
C. It is stored in NADH.
D. It joins with molecules of citric acid.

Correct answer: B

Rationale: During glycolysis, glucose undergoes a series of enzymatic reactions in the cytoplasm of the cell, resulting in its breakdown into two molecules of pyruvic acid. This process also generates ATP and NADH as energy carriers. Choice A is incorrect because glucose is not entirely lost, but rather converted into other molecules. Choice C is incorrect because NADH is a product of glycolysis, not a storage form for glucose. Choice D is incorrect as glucose does not join with molecules of citric acid during glycolysis, but rather in subsequent stages of cellular respiration.

3. Which of the following is not true about enzymes?

A. They catalyze reactions
B. They lower the activation energy needed
C. They have an active site
D. They are typically proteins

Correct answer: B

Rationale: Enzymes lower the activation energy needed for a reaction to occur, not raise it. By lowering the activation energy, enzymes facilitate reactions, making them occur more easily and rapidly. Choice A is correct as enzymes indeed catalyze reactions. Choice C is correct as enzymes have specific active sites where substrates bind. Choice D is correct as enzymes are commonly proteins, although some RNA molecules also exhibit catalytic properties.

4. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?

A. Both daughters will carry the disease.
B. Both sons will carry the disease.
C. One daughter may have the disease.
D. One son may have the disease.

Correct answer: C

Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.

5. Cytosine and thymine are known as:

A. Purines
B. Pyrimidines
C. Both
D. None of the above

Correct answer: B

Rationale: Cytosine and thymine are known as pyrimidines because they have a single carbon ring structure. Purines, on the other hand, have a double-ring structure. Choice A ('Purines') is incorrect because purines have a double-ring structure, unlike cytosine and thymine. Choice C ('Both') is incorrect as it implies they are both purines and pyrimidines, which is not true. Choice D ('None of the above') is incorrect because cytosine and thymine are indeed pyrimidines.