HESI A2
Biology HESI A2 Practice Test
1. Which part of cellular respiration produces the greatest amount of ATP?
- A. electron transport chain
- B. glycolysis
- C. citric acid cycle
- D. fermentation
Correct answer: A
Rationale: The electron transport chain (ETC) produces the greatest amount of ATP during cellular respiration. This process occurs in the inner mitochondrial membrane and involves the transfer of electrons through a series of protein complexes, creating a proton gradient that drives the synthesis of ATP. By utilizing the energy from the electron carriers NADH and FADH2 produced in earlier stages of cellular respiration, the ETC can generate a large amount of ATP efficiently through oxidative phosphorylation. Glycolysis only produces a small amount of ATP in comparison to the ETC. The citric acid cycle generates some ATP but not as much as the ETC. Fermentation does not produce ATP through oxidative phosphorylation and yields a much smaller amount of ATP compared to the ETC.
2. Choose the two bases that have two carbon rings:
- A. Adenine
- B. Cytosine
- C. Thymine
- D. Guanine
Correct answer: A
Rationale: Adenine and guanine have two carbon rings and are known as purines. These bases are found in nucleic acids such as DNA and RNA. Adenine (option A) and guanine (option D) are the correct choices as they both have two carbon rings in their molecular structure. Cytosine (option B) and thymine (option C) have a single carbon ring each, making them incorrect choices for bases with two carbon rings.
3. What kind of symbiosis exists between a pneumonia bacterium and a human?
- A. Mutualism
- B. Parasitism
- C. Commensalism
- D. Competition
Correct answer: B
Rationale: In the case of a pneumonia bacterium and a human, the relationship is best described as parasitism. The bacterium benefits by causing harm to the human host, while the human is negatively affected by the presence of the bacterium, leading to illness or infection. This is a classic example of a parasitic relationship where one organism benefits at the expense of the other. Mutualism (Choice A) is a type of symbiotic relationship where both organisms benefit from each other. Commensalism (Choice C) is a symbiotic relationship where one organism benefits, and the other is neither helped nor harmed. Competition (Choice D) refers to a relationship where both organisms are negatively affected by each other as they compete for resources.
4. During which phase is the chromosome number reduced from diploid to haploid?
- A. S phase
- B. interphase
- C. mitosis
- D. meiosis I
Correct answer: D
Rationale: The correct answer is 'meiosis I.' During meiosis I, the chromosome number is reduced from diploid to haploid through two rounds of division. Choice A ('S phase') is incorrect as the S phase is part of the cell cycle where DNA is replicated. Choice B ('interphase') is also incorrect as interphase is the phase where the cell prepares for division. Choice C ('mitosis') is incorrect as mitosis is a process where a diploid cell divides to produce two identical diploid daughter cells, maintaining the chromosome number.
5. During which phase of mitosis do the chromosomes align in the center of the cell?
- A. Prophase
- B. Metaphase
- C. Telophase
- D. Anaphase
Correct answer: B
Rationale: The correct answer is Metaphase. During Metaphase, the chromosomes line up along the center of the cell's equator, forming the metaphase plate. This alignment ensures that during the subsequent phase, Anaphase, the sister chromatids can separate and move towards opposite poles. Prophase is the initial phase of mitosis where chromosomes condense and the nuclear envelope breaks down. Telophase is the final phase of mitosis where two new nuclei form.
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