HESI A2
Biology HESI A2 Practice Test
1. Which part of cellular respiration produces the greatest amount of ATP?
- A. electron transport chain
- B. glycolysis
- C. citric acid cycle
- D. fermentation
Correct answer: A
Rationale: The electron transport chain (ETC) produces the greatest amount of ATP during cellular respiration. This process occurs in the inner mitochondrial membrane and involves the transfer of electrons through a series of protein complexes, creating a proton gradient that drives the synthesis of ATP. By utilizing the energy from the electron carriers NADH and FADH2 produced in earlier stages of cellular respiration, the ETC can generate a large amount of ATP efficiently through oxidative phosphorylation. Glycolysis only produces a small amount of ATP in comparison to the ETC. The citric acid cycle generates some ATP but not as much as the ETC. Fermentation does not produce ATP through oxidative phosphorylation and yields a much smaller amount of ATP compared to the ETC.
2. How many different types of nucleotides are there in DNA?
- A. one
- B. two
- C. four
- D. eight
Correct answer: C
Rationale: The correct answer is 'C: four.' DNA is composed of four different types of nucleotides: adenine, thymine, guanine, and cytosine. These nucleotides pair up in specific combinations to form the genetic code. Choices 'A: one,' 'B: two,' and 'D: eight' are incorrect because DNA consists of a set of four distinct nucleotides, not one, two, or eight.
3. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
4. Which of the following bases is not present in RNA?
- A. Adenine
- B. Thymine
- C. Uracil
- D. Cytosine
Correct answer: B
Rationale: Thymine is not present in RNA. RNA uses uracil as one of its bases, which pairs with adenine. In RNA, adenine does not pair with thymine as in DNA. Cytosine and guanine are the other two bases found in both RNA and DNA.
5. Which of the following organelles are responsible for producing cell energy?
- A. Mitochondrion and chloroplast
- B. Mitochondrion and nucleus
- C. Chloroplast and nucleus
- D. Chloroplast and lysosome
Correct answer: A
Rationale: The correct answer is A: Mitochondrion and chloroplast. Mitochondria and chloroplasts are the organelles responsible for producing cell energy through cellular respiration and photosynthesis, respectively. Choice B is incorrect because the nucleus is not involved in energy production. Choice C is incorrect as the nucleus is not an organelle that produces energy. Choice D is incorrect as lysosomes function in digesting waste materials, not in energy production.
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