HESI A2
Biology HESI A2 Practice Test
1. Which part of cellular respiration produces the greatest amount of ATP?
- A. electron transport chain
- B. glycolysis
- C. citric acid cycle
- D. fermentation
Correct answer: A
Rationale: The electron transport chain (ETC) produces the greatest amount of ATP during cellular respiration. This process occurs in the inner mitochondrial membrane and involves the transfer of electrons through a series of protein complexes, creating a proton gradient that drives the synthesis of ATP. By utilizing the energy from the electron carriers NADH and FADH2 produced in earlier stages of cellular respiration, the ETC can generate a large amount of ATP efficiently through oxidative phosphorylation. Glycolysis only produces a small amount of ATP in comparison to the ETC. The citric acid cycle generates some ATP but not as much as the ETC. Fermentation does not produce ATP through oxidative phosphorylation and yields a much smaller amount of ATP compared to the ETC.
2. Why is DNA important for metabolic activities of the cell?
- A. It controls the synthesis of enzymes.
- B. It stabilizes the cell wall.
- C. It initiates cell division.
- D. It prevents diffusion of nutrients.
Correct answer: A
Rationale: The correct answer is A. DNA plays a crucial role in metabolic activities by controlling the synthesis of enzymes. Enzymes are the biological catalysts that regulate and facilitate metabolic reactions within the cell. Choice B is incorrect because DNA is not involved in stabilizing the cell wall; that role is usually associated with other components like the cell membrane. Choice C is incorrect as cell division is primarily regulated by different processes and molecules, not directly by DNA. Choice D is incorrect because DNA is not related to preventing the diffusion of nutrients; instead, it is involved in coding for proteins that aid in various cellular functions.
3. In an example of a male with hemophilia and a female carrier, what percentage of the offspring is predicted to be carriers only?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the X chromosome with the hemophilia gene from the mother, as males have one X chromosome inherited from their mother. The female offspring will inherit one normal X chromosome from the father and one X chromosome with the hemophilia gene from the mother, making them carriers of the hemophilia trait. Therefore, 50% of the offspring will be carriers only. Option A (0%) is incorrect as female offspring will inherit the X chromosome with the hemophilia gene from the mother. Option B (25%) is incorrect as the female offspring will not be unaffected. Option D (100%) is incorrect as not all offspring will be carriers, only the female offspring.
4. Which of the following types of hormones can diffuse through the cell membrane to bind to receptors inside the cell and stimulate a chemical response to a target cell?
- A. fat-soluble hormones
- B. amino acid derivatives
- C. hydrophilic hormones
- D. water-soluble hormones
Correct answer: A
Rationale: The correct answer is A: fat-soluble hormones. Fat-soluble hormones are able to diffuse through the cell membrane to bind to receptors inside the cell. This is because they are lipophilic, allowing them to cross the lipid bilayer easily. Once inside the cell, fat-soluble hormones can directly affect gene expression or cell function. Choice B, amino acid derivatives, and choice C, hydrophilic hormones, are not able to diffuse through the cell membrane as they are not lipophilic. Therefore, they cannot bind to receptors inside the cell. Choice D, water-soluble hormones, also cannot diffuse through the cell membrane as it is hydrophilic, making it unable to reach receptors inside the cell.
5. Which, if any, of the following statements are true?
- A. Water boils at approximately 100°C (212°F) at standard atmospheric pressure
- B. The boiling point is the temperature at which the vapor pressure is higher than the atmospheric pressure around the water
- C. Water boils at a lower temperature in areas of lower pressure
- D. A and C are true
Correct answer: D
Rationale: Both statements A and C are true. Water indeed boils at approximately 100°C (212°F) at standard atmospheric pressure. However, water boils at a lower temperature in areas of lower pressure due to the decreased atmospheric pressure, which affects the vapor pressure and boiling point of water. Statement B is incorrect because the boiling point is the temperature at which the vapor pressure equals the external pressure (atmospheric pressure in this case), not when it is higher.
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