HESI A2
Biology HESI A2 Practice Test
1. Which two bases are purines?
- A. Adenine (A)
- B. Cytosine (C)
- C. Thymine (T)
- D. Guanine (G)
Correct answer: A
Rationale: Adenine (A) and guanine (G) are the two bases that are purines. Purines are characterized by a double-ring structure containing two carbon rings, distinguishing them from pyrimidines. Adenine and guanine are purines because they possess this unique double-ring structure. Therefore, choices A and D, adenine and guanine, respectively, are the correct answers. Choices B and C, cytosine and thymine, are pyrimidines and do not exhibit the double-ring structure characteristic of purines.
2. Which organelle would you expect to be present in a cell responsible for detoxifying multiple molecules?
- A. rough ER
- B. smooth ER
- C. lysosome
- D. Golgi apparatus
Correct answer: B
Rationale: The smooth endoplasmic reticulum (ER) is the organelle responsible for detoxifying multiple molecules in a cell. It contains enzymes that help break down toxins and drugs, making it an essential organelle for detoxification processes. The rough ER, lysosome, and Golgi apparatus do not play direct roles in detoxification. The rough ER is mainly involved in protein synthesis and transport. Lysosomes are responsible for digestion and recycling within the cell. The Golgi apparatus is involved in modifying, sorting, and packaging proteins for secretion or for use within the cell.
3. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?
- A. 0 female : 2 males
- B. 1 female : 0 males
- C. 1 female : 2 males
- D. 2 females : 1 male
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.
4. Why is DNA important for metabolic activities of the cell?
- A. It controls the synthesis of enzymes.
- B. It stabilizes the cell wall.
- C. It initiates cell division.
- D. It prevents diffusion of nutrients.
Correct answer: A
Rationale: The correct answer is A. DNA plays a crucial role in metabolic activities by controlling the synthesis of enzymes. Enzymes are the biological catalysts that regulate and facilitate metabolic reactions within the cell. Choice B is incorrect because DNA is not involved in stabilizing the cell wall; that role is usually associated with other components like the cell membrane. Choice C is incorrect as cell division is primarily regulated by different processes and molecules, not directly by DNA. Choice D is incorrect because DNA is not related to preventing the diffusion of nutrients; instead, it is involved in coding for proteins that aid in various cellular functions.
5. Why doesn't an antibiotic work for treating the flu?
- A. The antibiotic is for a different type of infection
- B. The antibiotic is not effective against viruses
- C. The antibiotic is not prescribed in a high enough dosage
- D. None of the above
Correct answer: B
Rationale: The correct answer is B. Antibiotics are used to treat bacterial infections, not viral infections like the flu. The flu is caused by a virus, and antibiotics are ineffective against viruses. Choice A is incorrect because it does not address the fact that antibiotics do not work on viruses. Choice C is incorrect as the issue is not related to the dosage amount, but rather the nature of the infection. Choice D is incorrect as there is a specific reason why antibiotics do not work for the flu.
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