HESI A2
HESI A2 Biology Practice Test
1. Which is true of the term Phenotype?
- A. It is the genetic code
- B. Phenotype determines genotype
- C. Genotype determines phenotype
- D. Genotype, epigenetic factors, and environmental factors determine phenotype
Correct answer: D
Rationale: The term "phenotype" refers to the observable characteristics or traits of an organism, which are determined by a combination of genotype (genetic makeup), epigenetic factors (modifications to gene expression), and environmental factors (external influences and experiences). Genotype, epigenetic factors, and environmental factors all play a role in determining an individual's phenotype, making option D the correct statement. Options A, B, and C are incorrect because the phenotype is not the genetic code, the phenotype does not determine the genotype, and it is the genotype that influences the phenotype, not the other way around.
2. What is the role of ribosomes in the cell?
- A. Break down cellular waste
- B. Organize cellular division
- C. Synthesize proteins
- D. Provide cellular structure
Correct answer: C
Rationale: The correct answer is C: Synthesize proteins. Ribosomes are responsible for protein synthesis by linking amino acids together. Choice A is incorrect because ribosomes do not break down cellular waste. Choice B is incorrect as ribosomes do not organize cellular division. Choice D is incorrect because ribosomes do not provide cellular structure.
3. Why do high-salt content foods not require refrigeration to prevent spoilage?
- A. Osmosis
- B. Diffusion
- C. Active transport
- D. Passive transport
Correct answer: A
Rationale: Osmosis is the natural process that prevents high-salt content foods from spoiling without the need for refrigeration. Osmosis involves the movement of water across a semi-permeable membrane from an area of lower solute concentration (water) to an area of higher solute concentration (salt). In high-salt content foods, the salt acts as a preservative by drawing moisture out of bacteria or other microorganisms, making it difficult for them to survive and spoil the food. This process helps in preserving the food and preventing spoilage even without refrigeration. Choices B, C, and D are incorrect because they do not involve the specific mechanism of water movement in response to the salt concentration in high-salt content foods.
4. What event occurs during telophase?
- A. The nuclear envelope disappears.
- B. Organelles double in number.
- C. Chromosomes separate.
- D. Two nuclei are formed.
Correct answer: D
Rationale: During telophase, the final stage of mitosis, the separated chromosomes reach opposite poles of the cell. At this stage, a new nuclear envelope forms around each set of chromosomes, creating two distinct nuclei. This marks the completion of cell division. Choices A, B, and C are incorrect because the disappearance of the nuclear envelope typically occurs during prophase, organelles do not double in number during telophase, and chromosomes separate during anaphase, not telophase.
5. Which two bases are purines?
- A. Adenine (A)
- B. Cytosine (C)
- C. Thymine (T)
- D. Guanine (G)
Correct answer: A
Rationale: Adenine (A) and guanine (G) are the two bases that are purines. Purines are characterized by a double-ring structure containing two carbon rings, distinguishing them from pyrimidines. Adenine and guanine are purines because they possess this unique double-ring structure. Therefore, choices A and D, adenine and guanine, respectively, are the correct answers. Choices B and C, cytosine and thymine, are pyrimidines and do not exhibit the double-ring structure characteristic of purines.
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