HESI A2
HESI A2 Biology Practice Test
1. Which is true of the term Phenotype?
- A. It is the genetic code
- B. Phenotype determines genotype
- C. Genotype determines phenotype
- D. Genotype, epigenetic factors, and environmental factors determine phenotype
Correct answer: D
Rationale: The term "phenotype" refers to the observable characteristics or traits of an organism, which are determined by a combination of genotype (genetic makeup), epigenetic factors (modifications to gene expression), and environmental factors (external influences and experiences). Genotype, epigenetic factors, and environmental factors all play a role in determining an individual's phenotype, making option D the correct statement. Options A, B, and C are incorrect because the phenotype is not the genetic code, the phenotype does not determine the genotype, and it is the genotype that influences the phenotype, not the other way around.
2. In an example of a male with hemophilia and a female carrier, what ratio of the offspring are predicted neither to carry nor to manifest the disease?
- A. 0 females : 1 male
- B. 1 female : 1 male
- C. 1 female : 0 males
- D. 2 females : 1 male
Correct answer: D
Rationale: In this scenario, the male offspring will inherit the Y chromosome from the father and the X chromosome from the carrier mother. As a result, they will not have the hemophilia gene. The female offspring will inherit one X chromosome from the mother, which does not carry the hemophilia gene, and one X chromosome from the father, which does not exist due to the Y chromosome. Therefore, all female offspring will not carry or manifest hemophilia, resulting in a ratio of 2 females to 1 male. Choice A is incorrect because it does not account for the female offspring. Choices B and C are incorrect as they do not reflect the correct ratio based on the inheritance pattern of hemophilia.
3. How do animal cells divide?
- A. Through a contractile ring
- B. Via a cell plate
- C. Both methods
- D. None of the above
Correct answer: A
Rationale: Animal cells divide through a contractile ring made of actin and myosin filaments. The ring contracts, pinching the cell membrane in the middle to form two daughter cells. Plant cells use a cell plate due to their rigid cell walls, making choices B and C incorrect. Choice D is incorrect as animal cells do use the contractile ring method for division.
4. What type of cells possess a cell membrane?
- A. Prokaryotic cells only
- B. Eukaryotic cells only
- C. Both prokaryotic and eukaryotic cells
- D. None of the above
Correct answer: C
Rationale: Cell membranes are present in both prokaryotic and eukaryotic cells. The cell membrane serves as a barrier that encloses the cell contents and regulates the entry and exit of substances in and out of the cell. It is a fundamental structure found in all types of cells, regardless of whether they are prokaryotic (lacking a nucleus) or eukaryotic (containing a nucleus). Choice A is incorrect because eukaryotic cells also possess cell membranes. Choice B is incorrect as prokaryotic cells, such as bacteria, also have cell membranes. Choice D is incorrect as both prokaryotic and eukaryotic cells have cell membranes.
5. Cytosine and thymine are known as:
- A. Purines
- B. Pyrimidines
- C. Both
- D. None of the above
Correct answer: B
Rationale: Cytosine and thymine are known as pyrimidines because they have a single carbon ring structure. Purines, on the other hand, have a double-ring structure. Choice A ('Purines') is incorrect because purines have a double-ring structure, unlike cytosine and thymine. Choice C ('Both') is incorrect as it implies they are both purines and pyrimidines, which is not true. Choice D ('None of the above') is incorrect because cytosine and thymine are indeed pyrimidines.
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