HESI A2
HESI A2 Biology 2024
1. In which phase of mitosis do new nuclear membranes form around sets of chromosomes?
- A. Prophase
- B. Anaphase
- C. Telophase
- D. Interphase
Correct answer: C
Rationale: The correct answer is C, Telophase. During telophase, the final phase of mitosis, new nuclear membranes form around sets of chromosomes at the opposite poles of the cell. This process marks the completion of nuclear division in mitosis. Choices A, B, and D are incorrect because in prophase, chromosomes condense but nuclear membranes are not formed; in anaphase, chromosomes separate and move to opposite poles but no new nuclear membranes are formed; and in interphase, the cell prepares for division but nuclear membranes are not forming around sets of chromosomes.
2. Enzymes can _ reactions.
- A. Catalyze
- B. Inhibit
- C. Stop
- D. None of the above
Correct answer: A
Rationale: Enzymes function as catalysts that promote and accelerate chemical reactions in biological systems. They do this by lowering the activation energy required for the reactions to occur, thereby speeding up the process without being consumed in the reaction. Enzymes facilitate reactions rather than inhibiting or stopping them. Therefore, the correct answer is 'Catalyze.' 'Inhibit' and 'Stop' are incorrect because enzymes do not hinder or halt reactions but rather enhance them.
3. During which phase of mitosis do the chromosomes align in the center of the cell?
- A. Prophase
- B. Metaphase
- C. Telophase
- D. Anaphase
Correct answer: B
Rationale: The correct answer is Metaphase. During Metaphase, the chromosomes line up along the center of the cell's equator, forming the metaphase plate. This alignment ensures that during the subsequent phase, Anaphase, the sister chromatids can separate and move towards opposite poles. Prophase is the initial phase of mitosis where chromosomes condense and the nuclear envelope breaks down. Telophase is the final phase of mitosis where two new nuclei form.
4. Which component is not found in the nucleotide of DNA?
- A. Simple sugar
- B. Nitrogen base
- C. Phosphate group
- D. Citric acid
Correct answer: D
Rationale: Citric acid is not found in the nucleotide of DNA. A DNA nucleotide is composed of a simple sugar (deoxyribose), a nitrogen base (adenine, thymine, cytosine, or guanine), and a phosphate group. Citric acid is not part of DNA nucleotides; instead, it is involved in the citric acid cycle of cellular respiration. Choices A, B, and C are essential components of DNA nucleotides, making them incorrect answers.
5. Which is not part of a nucleic acid?
- A. Sulfate
- B. Phosphate
- C. Carbon
- D. Nitrogen
Correct answer: A
Rationale: Sulfate is not part of a nucleic acid. Nucleic acids, such as DNA and RNA, are composed of nucleotide units, which consist of a phosphate group, a sugar molecule (ribose in RNA and deoxyribose in DNA), and a nitrogenous base. Carbon and nitrogen are essential elements found in nucleic acids, while sulfate is not a component of nucleic acid structure. Therefore, the correct answer is A: Sulfate.
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